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Medical Forum / General / General / June 2006Goat milk medicine oked
Great work , now all medicines will be made this way bbc.co.uk Go-ahead for 'pharmed' goat drug The goat produces a human anti-clotting protein in its milk The first medicine produced from a genetically modified animal has been recommended for use in Europe. The European Medicines Agency (EMEA) has reversed an earlier decision not to issue a licence for the drug, ATryn, after taking further expert advice. This is a technology which has the potential to dramatically change the way in which expensive biological drugs are developed for the commercial marketplace," he told the BBC News website. In a statement on the company's website, Professor Isobel Walker, consultant haematologist at the Glasgow Royal Infirmary, UK, said: "It is a good day for European patients with congenital anti-thrombin deficiency and for their physicians." M.K. Gandhi is known to drink Gaots Milk as to many Nomads from Rajasthan and Gujrat especially when some is ill he/she is prescribed Goats Milk. Also many people have wrote about Hindu's Drinking Cows Urine, Which is 100% true. there are many medicinal properties in the Cows Urine, which the mordern since is still dicovering. BTW for over three decades the number 1 prescribed medicine in the West was Estrogen (100% Purified Mare's Urine). > Great work , now all medicines will be made this way > [quoted text clipped - 16 lines] > is a good day for European patients with congenital anti-thrombin > deficiency and for their physicians." > Great work , now all medicines will be made this way > [quoted text clipped - 16 lines] > is a good day for European patients with congenital anti-thrombin > deficiency and for their physicians." Are they refering to ATIII anti-thrombin III? So these people buy a goat and suck for milk or how does it work? >> bbc.co.uk >> Go-ahead for 'pharmed' goat drug [quoted text clipped - 18 lines] > >So these people buy a goat and suck for milk or how does it work? It's a genetic engineering technique, where the gene for the protein of interest is emplaced in the goat's genome in a location that causes it to be expressed by cells that are producing milk proteins. Essentially, it's the same technique now used to cause bacteria to produce human insulin, human growth hormone and other materials commercially, but the proteins are refined from milk instead of from bacterial culture medium. This technique was developed some years ago. IIRC, the first protein engineered to be expressed in goat milk was sericin, the protein of silk. The "news" here is that a drug produced by this technique is being licensed for medical use. The same technique is also used to get plants to produce alien proteins. The implementation here has a number of potentially disastrous problems which aren't being adequately addressed, IMHO. > >> bbc.co.uk > >> Go-ahead for 'pharmed' goat drug [quoted text clipped - 35 lines] > The implementation here has a number of potentially disastrous problems > which aren't being adequately addressed, IMHO. I guess every time the goat dies then they have to come up with a new one. Don't know anything about lactating goats. >> >> bbc.co.uk >> >> Go-ahead for 'pharmed' goat drug [quoted text clipped - 38 lines] >I guess every time the goat dies then they have to come up with a new >one. Don't know anything about lactating goats. They have a line of goats that makes the protein. So they just breed more. In one case a few years back, I recall it was estimated that a herd of about 200 goats would be used to provide adequate supply of the drug. Obviously, that depends on the drug, as well as on production level. But it gives the idea. bae's explanation was right on. bob >> >> bbc.co.uk >> >> Go-ahead for 'pharmed' goat drug [quoted text clipped - 38 lines] >I guess every time the goat dies then they have to come up with a new >one. Don't know anything about lactating goats. Once they've got it integrated into the genome, they can breed more goats using neolithic methods. From the synopsis above, I assume that a barn full of milk goats fed hay and grain and tended by farm workers, plus a facility to extract the desired protein from the milk is a cheaper method of production than a high tech facility full of microbial reactors fed expensive purified chemicals and tended by technicians plus a similar facility for extracting the desired protein from the culture medium. I don't think anybody is ready to replace a lot of mulberry trees, caterpillars and very low paid Asian workers with the product of "silk goats" yet, however. > Once they've got it integrated into the genome, they can breed more goats > using neolithic methods. [quoted text clipped - 9 lines] > caterpillars and very low paid Asian workers with the product of "silk > goats" yet, however. One small vial about an inch high of recom. Factor VII is about 4 thousand dollars.I seriously doubt any of the goat herders will get much money out of it and the price will not go down that much. The price in the market place doesn't always reflect the cost of production. |
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