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Medical Forum / General / General / April 2006

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To avoid with glomerulonephritis

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Spike - 02 Apr 2006 18:42 GMT
Hi all,
I was recently diagnosed with autoimmune glomerulonephritis from
mesangial deposits of IgA (not particularly evil form). How cool.

The nephrologist told me a few things which seemed strange to me, and I
would appreciate a second opinion.

He told me I should not do agonistic activity (sorry I am not sure of
the translation from Italian, I intend to mean that performing sports
lightly is ok but serious activity in a serious team is not). Why? I
would appreciate an explanation of what happens in the blood during
sports. I thought sports would raise the endorphins and I thought this
was good for autoimmune diseases.

Also, martial arts are not ok if there are hits, *even if* the hits
would be on parts of the body other than the kidneys! (yes he really
said so!). Why??

He said to moderate aspirins to max 1g/day, and no NSAIDs, and this I
understand, but he also said to also moderate acetaminophen to max
1g/day !!? I *never* read anywhere that acetaminophen could be
neprhotoxic! (for aspirin and NSAIDs, I think I did) And this worries me
alot because now I am without options for anti inflammatories, and I
occasionally need them in significant doses for some tendonitis which I
occasionally have. Please comment on acetaminophen.

One time in the past I had to stay 2 days in bed because of flank pain
(I did not know the cause at the time). If this would happen again, he
said my only option is to rest in bed as I did. No meds. I understand
the thing, since my condition is not so serious. Just a question of
principle: would a steroidal antiinflammatory in theory help? (I think
it is an inflammation after all, and an autoimmune one, so...)

I forgot to ask if I can drink alcohol or not. That time that I had to
stay 2 days in bed, after a few days when I had recovered I drank some
alcohol (a very small amount). The flank pain came back for half a day.
Any comment? Is alcohol nephrotoxic?

Last question: for any dangerous thing I mentioned (heavy sports,
aspirin, alcohol...), is it a too dangerous approach to do the following:
1- perform the dangerous thing increasingly
2- monitor the urine, if I see blood I know that "I have gone too far,
next time do much less"

You know... if I could do this it would be great... otherwise I have to
live like an handicapped because I don't know where my limit is...
however if you tell me that there can be damages even if I don't see any
blood or that the amount of blood I see is not proportional to the
damages, I won't do that.

Thanks a lot
Spike
Twittering One - 02 Apr 2006 18:56 GMT
"Spike, Hail, Thee ~
Tres Kewl Dude ~ !"
~ Twittering LSTOO & Folly IAG
Twittering One - 02 Apr 2006 19:01 GMT
"Twittering,
Who's Spike ~ ?"
~ Breguet

"Ms.
Joan River's Yorkie."
~ Folly
Jason - 02 Apr 2006 20:06 GMT
> Hi all,
> I was recently diagnosed with autoimmune glomerulonephritis from
[quoted text clipped - 48 lines]
> Thanks a lot
> Spike

Spike,
The best thing for you to do is to read this book. All of your questions
will be answered. It's written in such a way that anyone that is not a
doctor or involved in the medical profession could easily understand it.

COPING WITH KIDNEY DISEASE--A 12 STEP TREATMENT PROGRAM TO HELP YOU AVOID
DIALYSIS
by Mackenzie Walser, M.D.  (He is a professor at Johns Hopkins University
School of Medicine. He is a kidney specialist.

I hope this helps.
Jason

Signature

NEWSGROUP SUBSCRIBERS MOTTO
We respect those subscribers that ask for advice or provide advice.
We do NOT respect the subscribers that enjoy criticizing people.

REP - 03 Apr 2006 11:03 GMT
> Hi all,
> I was recently diagnosed with autoimmune glomerulonephritis from
> mesangial deposits of IgA (not particularly evil form). How cool.

Neato. I have FSGS; I can answer some of your questions.

> The nephrologist told me a few things which seemed strange to me, and I
> would appreciate a second opinion.
>
> He told me I should not do agonistic activity (sorry I am not sure of
> the translation from Italian,

No need to apologize; I'm sorry I can only answer in English!

>I intend to mean that performing sports
> lightly is ok but serious activity in a serious team is not). Why? I
> would appreciate an explanation of what happens in the blood during
> sports. I thought sports would raise the endorphins and I thought this
> was good for autoimmune diseases.

I cannot explain in great detail, but in short, intense activity raises
creatinine levels, which your kidneys can no longer clear as
efficiently. Raise these levels too much too often (and this very
simplified), your kidneys won't be able to clear creatinine anymore.

Activities like yoga, tai chi and other non-contact sports that aren't
as demanding as soccer (football), rugby, karate, etc are thought to be
good for cardiovascular health (a concern with kidney patients) as well
as the endorphin idea you raise. Anything that leaves you wringing wet
with sweat and out of breath may be too intense.

> Also, martial arts are not ok if there are hits, *even if* the hits
> would be on parts of the body other than the kidneys! (yes he really
> said so!). Why??

I am guessing, but I think this might have somethign to do with lactic
acidosis, which can happen with deep bruising.

> He said to moderate aspirins to max 1g/day, and no NSAIDs, and this I
> understand, but he also said to also moderate acetaminophen to max
[quoted text clipped - 3 lines]
> occasionally need them in significant doses for some tendonitis which I
> occasionally have. Please comment on acetaminophen.

I have focal segmental glomerulosclerosis, a different kidney disease,
and I am not limited in my acetominophen intake. It may be because of
some other drugs you are taking, but be sure to ask your nephrologist
for an explanation.

> One time in the past I had to stay 2 days in bed because of flank pain
> (I did not know the cause at the time). If this would happen again, he
> said my only option is to rest in bed as I did. No meds. I understand
> the thing, since my condition is not so serious. Just a question of
> principle: would a steroidal antiinflammatory in theory help? (I think
> it is an inflammation after all, and an autoimmune one, so...)

Generall speaking, no. Steroids do not help IgA nephropathy, but fishoil
has shown some promise. Steroids can be taken for other conditions as
needed, and of corse, if your nephrologist thinks it will help your
condition.

> I forgot to ask if I can drink alcohol or not. That time that I had to
> stay 2 days in bed, after a few days when I had recovered I drank some
> alcohol (a very small amount). The flank pain came back for half a day.
> Any comment? Is alcohol nephrotoxic?

Alcohol in moderation is generally not a problem; however, if it bothers
you, avoid it!

> Last question: for any dangerous thing I mentioned (heavy sports,
> aspirin, alcohol...), is it a too dangerous approach to do the following:
> 1- perform the dangerous thing increasingly
> 2- monitor the urine, if I see blood I know that "I have gone too far,
> next time do much less"

Not a great idea, because the damage happens over time and may not show
up in a dipstick. Your spot check for protein, for example, may be fine
but your 24 hour number may be up.

> You know... if I could do this it would be great... otherwise I have to
> live like an handicapped because I don't know where my limit is...
> however if you tell me that there can be damages even if I don't see any
> blood or that the amount of blood I see is not proportional to the
> damages, I won't do that.

You don't have to live like an invalid; you may just have to find
activities that are less likely to make your condition worse. I know it
sucks to give up things you like to do, like sports, but remember, you
will be helping yourself live longer and live without needing dialysis.
While you're feeling well, that may not seem real, but imagine having to
be hooked up to a machine for 4 hours a day 3 or 4 times a week - and
feeling weak and sick. By being careful now, you can help avoid that!

Be sure to ask your doctor ALL your questions; he can give you the best
information and explanation of his instructions.

Good luck and stay well!

Signature

"Did Father shoot him? I will eat Grandfather for dinner."
- Helen Keller, on learning of the death of her grandfather

John Who - 03 Apr 2006 15:59 GMT
> Neato. I have FSGS; I can answer some of your questions.

Man thanks a real lot! Very helpful

Best of luck with your FSGS..

Spike
REP - 04 Apr 2006 05:34 GMT
> > In article <44300c97$0$92487$892e0abb@auth.newsreader.octanews.com>,
>  > ...
> > Neato. I have FSGS; I can answer some of your questions.
>
> Man thanks a real lot! Very helpful

Glad I could help, but remember, ask your doctor!

> Best of luck with your FSGS..

Thanks! I hope your IgA nephropathy is the type that never gets worse.

Signature

"Did Father shoot him? I will eat Grandfather for dinner."
- Helen Keller, on learning of the death of her grandfather

daniele.focosi@gmail.com - 04 Apr 2006 19:51 GMT
It seems to me your nephrologist was quite confused. Try to get a
second opinion. If you have been diagnosed with IgA nephropathy, this
is an autoimmune disease common in the Mediterranean area that is
different from FSGS. If you like you can read freely some official
medical reviews on http://www.sin-italy.org/jnonline/Vol18n4/354.html.

In bocca al lupo!

Daniele
www.mm.interhealth.info
Spike - 04 Apr 2006 23:39 GMT
Thanks for the interesting link

> ...IgA nephropathy, this
> is an autoimmune disease common in the Mediterranean area that is
> different from FSGS.

(Nobody said that it's the same, I just happened to be answered here by
someone with FSGS)
 
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