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Medical Forum / General / General / January 2006Vitamin E-deficiency / nerve regeneration
<<snip>> This result confirm the vitamin E to be an important factor of the normal process of nerve regeneration <<snip>> : Arch Ital Anat Embriol 1990 Apr-Jun;95(2):155-65 Related Articles, Books, LinkOut Effect of vitamin E-deficiency on regeneration of the sciatic nerve. Cecchini T, Cuppini R, Ciaroni S, Del Grande P. Istituto di Scienze Morfologiche, Universita di Urbino, Italy. The regeneration of the sciatic nerve fibres was studied in both normal and vitamin E-deficient rats at 30 and 60 days after crush. The vitamin E is involved in one of the most important mechanisms of protection against peroxidation of plasma membrane lipids; the plasma membrane plays certainly a role in nerve regeneration. Both the diameter and the total number of myelinated nerve fibres was calculated at different times. The number of myelinated fibres in the undenervated deficient animals was lower than that found in the undenervated normals animals. Following the nerve crush, in normal animals after two months the number of myelinated fibres exceeded the number found in undenervated normal animals, whereas in the deficient rat nerves it was significantly lower than in the corresponding controls and moreover it did not even reach the number found in the nerves of undenervated deficient rats. Finally, the caliber distribution of myelinated fibres in undenervated and denervated deficient rats shows a relative percent increase in the number of greatest axons and a decrease in smaller axons. This result confirm the vitamin E to be an important factor of the normal process of nerve regeneration. PMID: 2078094 [PubMed - indexed for MEDLINE] -------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking > <<snip>> > This result confirm the vitamin > E to be an important factor of the normal process of nerve regeneration > <<snip>> I do NOT understand? What does Vitamin E have to do with iron, Mr. Food Faddist? Am J Vet Res. 2006 Jan;67(1):120-6. Related Articles, Links Evaluation of the risk of motor neuron disease in horses fed a diet low in vitamin E and high in copper and iron. Divers TJ, Cummings JE, de Lahunta A, Hintz HF, Mohammed HO. Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853. Objective-To determine whether equine motor neuron disease (EMND) could be induced in adult horses fed a diet low in vitamin E and high in copper and iron. Animals-59 healthy adult horses. Procedure-Horses in the experimental group (n = 8) were confined to a dirt lot and fed a concentrate low in vitamin E and high in iron and copper in addition to free-choice grass hay that had been stored for 1 year. Control horses (n = 51) were fed a concentrate containing National Research Council-recommended amounts of copper, iron, and vitamin E. The hay fed to control horses was the same as that fed to experimental horses, but it had not been subjected to prolonged storage. Control horses had seasonal access to pasture, whereas experimental horses had no access to pasture. Horses that developed clinical signs of EMND were euthanatized along with an age-matched control horse to determine differences in hepatic concentrations of vitamin E, vitamin A, copper, iron, and selenium. Results-4 experimental horses developed clinical signs of EMND. Plasma concentrations of vitamin E decreased in all 8 experimental horses. There were no significant changes in plasma concentrations of vitamin A, selenium, and copper or serum concentrations of ferritin. There were no significant differences in those analytes between experimental horses with EMND and experimental horses that did not develop EMND. No control horses developed EMND. Conclusions and Clinical Relevance-Results suggest that lack of access to pasture, dietary deficiency of vitamin E, or excessive dietary copper are likely risk factors for EMND. PMID: 16426221 [PubMed - in process] -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking What a load of horsesh*t. . .<snicker> Sylvia |
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