Metronidazole dosage question

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Linda S. - 29 Nov 2005 14:03 GMT

What's the minimum effective dosage for a teenager in the treatment of
trichomoniasis? I've seen 2-g one time only, 1-g bid one day only,
250-mg tid 7 days, 500-mg bid 7 days. But considering the bad side
effects and carcinogenic nature of this drug, I am trying to see what
other people think about lower dosages. Would either a 1-g one time
only or say 750-mg bid one day only be enough?

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Sbharris[atsign]ix.netcom.com - 29 Nov 2005 20:29 GMT

> What's the minimum effective dosage for a teenager in the treatment of
> trichomoniasis? I've seen 2-g one time only, 1-g bid one day only,
> 250-mg tid 7 days, 500-mg bid 7 days. But considering the bad side
> effects and carcinogenic nature of this drug, I am trying to see what
> other people think about lower dosages. Would either a 1-g one time
> only or say 750-mg bid one day only be enough?

The more you try to game the system by going to the thinner doses, the
more chance you have of failing. So it depends on your method of
feedback. If you have a good method to know you're infected, then you
can try the lower amount and double it (in duration or dose) if it
doesn't work.

And stop trying to be like those New Yorkers who want the A salad with
the B dressing but without the C and D and can you get F ala carte.
You probably aren't going to tip large enough for that.

SBH

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Steven Bornfeld - 30 Nov 2005 03:09 GMT

>>What's the minimum effective dosage for a teenager in the treatment of
>>trichomoniasis? I've seen 2-g one time only, 1-g bid one day only,
[quoted text clipped - 14 lines]
>
> SBH

Oh, Steven, I'd NEVER do that!!

Steve

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Linda S. - 02 Dec 2005 22:59 GMT

>> What's the minimum effective dosage for a teenager in the treatment of
>> trichomoniasis? I've seen 2-g one time only, 1-g bid one day only,
[quoted text clipped - 14 lines]
>
>SBH

I think I found a partial answer: Most web sites in the UK/Austr/NZ on
trich says to take 800 mg total per 24 hrs for 5 days. For single-dose
treatment, "CONCLUSION: A single 1.5-g dose of metronidazole has
efficacy equivalent to a single 2-g dose for the treatment of T
vaginalis vaginitis." Obstet Gynecol. 1997 May;89(5 Pt 1):699-703.

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