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Medical Forum / General / General / October 2005

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"Nobody expects the Spanish Influenza!"

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msadkins04@yahoo.com - 07 Oct 2005 02:51 GMT
Are they going to develop a vaccine for this "recovered" virus?
Viruses aren't life, just simple genetic strands with protein coats.
Do they really need to be preserved under laboratory conditions or
frozen in order to be recovered?  Is there any reason why remains dug
up from a graveyard (with or without mischief in mind -- remains are
often moved for land development, etc.) couldn't result in exposure to
this virus and a new pandemic?  With 20 million victims and easy access
to death records, it wouldn't be too difficult to find them.  And that
was back before the advent of commercial plane travel.  Imagine the
infection rate today.  Not exactly 12 Monkeys, but one hell of a
problem.  I don't know what would be left of the remains...I would
guess that in many cases bones and powder, the latter easily airborn,
hence easily inhaled by anyone carelessly handling them.  They weren't
so big on airtight coffins back then, so anaerobic putrifaction
wouldn't be that common...

Mark Adkins
msadkins04@yahoo.com
David Wright - 07 Oct 2005 05:04 GMT
>Are they going to develop a vaccine for this "recovered" virus?

No need.  They're comparing it to the bird flu to see what they have
in common.

>Viruses aren't life, just simple genetic strands with protein coats.
>Do they really need to be preserved under laboratory conditions or
>frozen in order to be recovered?

Just because they aren't alive doesn't mean they're indestructible.
They're strings of nucleic acids and they do break down over time.
Influenza is less fragile than, say, HIV, but it still degrades.

 -- David Wright :: alphabeta at prodigy.net
    These are my opinions only, but they're almost always correct.
    "If you can't say something nice, then sit next to me."
                                -- Alice Roosevelt Longworth
msadkins04@yahoo.com - 08 Oct 2005 17:46 GMT
> >Viruses aren't life, just simple genetic strands with protein coats.
> >Do they really need to be preserved under laboratory conditions or
[quoted text clipped - 3 lines]
> They're strings of nucleic acids and they do break down over time.
> Influenza is less fragile than, say, HIV, but it still degrades.

Maybe not fast enough.  See:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1
671114&dopt=Citation


http://www.crystalinks.com/mum.html

In the first instance, the survival was after considerable soil mixing.

In the second instance, the viral remains were considerable but
partial, but that was after more than 1,000 years.

Can you cite a study demonstrating that influenza virus is
unrecoverable and non-virulent after less than 100 years interment in
dry graves in (say) a desert area?
David Wright - 08 Oct 2005 22:36 GMT
>> >Viruses aren't life, just simple genetic strands with protein coats.
>> >Do they really need to be preserved under laboratory conditions or
[quoted text clipped - 18 lines]
>unrecoverable and non-virulent after less than 100 years interment in
>dry graves in (say) a desert area?

Not offhand, but so what?  It wasn't my idea to go after it in people
buried in permafrost.

 -- David Wright :: alphabeta at prodigy.net
    These are my opinions only, but they're almost always correct.
    "If you can't say something nice, then sit next to me."
                                -- Alice Roosevelt Longworth
msadkins04@yahoo.com - 09 Oct 2005 01:57 GMT
> >> >Viruses aren't life, just simple genetic strands with protein coats.
> >> >Do they really need to be preserved under laboratory conditions or
[quoted text clipped - 26 lines]
>      "If you can't say something nice, then sit next to me."
>                                  -- Alice Roosevelt Longworth

I didn't say permafrost.  I *suppose* that under some usages of the
term "desert" might refer to permafrost, but there are other kinds of
deserts, and I wasn't, strictly speaking, restricting the question to
deserts -- merely specifying them as a kind of exemplar of first
preference.

Mark Adkins
msadkins04@yahoo.com
 
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