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Medical Forum / General / General / September 2005

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Body/Gastric pH

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kumar - 24 Sep 2005 11:18 GMT
Hello,

I have few confusions:-

1.More gastric acid secretion may contribute more bicarbonate to body
as alkaline tide & may loose more hydrogen & Clorine as HCl. So foods,
with low pH may discourage gastric acid secretion & so may not
contribute bicarbonate to body--so can have acidic effect into the
body. Is it correct?

2.Two type of medicines are used to control gastric acidity--antacids &

acid blockers. Antacids being alkaline, neutralize gastric acid & may
attract more acid secretion resulting into more bicarbonate into
body--so alkalizing effect. Acid blokers on the other hand, just stop
acid secretion & may not contribute bicarbonate into the body--so it
may cause acidic effect into body. Is it correct?

The above aspects may hold great importance in understanding acid/base
balance of body esp. when more or less gastric acid secretion may have
opposite effect into the body.

Pls inform me accordingly.

Best Wishes.
Squiggles - 24 Sep 2005 13:21 GMT
Hi,

I'm interested in your post and the replies, as I take
lithium (carbonate) and the acid/base balance may be
influenced.  I would like to know which foods are good
when taking this drug.  I notice that drinking sodas
are conducive to lowering the impact of a sudden surge
when the lithium is too high.

Thank you.

Squiggles
MobiusDick - 28 Sep 2005 19:59 GMT
It is not quite as simple as you have laid out. The H2 antagonists like
Tagamet and the higher level drugs like Nexium and Protonix stop acid
secretion in the stomach. Bicarbonate is not formed in the stomach
itself unles you take baking soda or an antacid.

Taking an antacid will not necessarily cause HCl secretion if taken
with after eating. Eating itself is the precipitator of gastric
secretion.

Drinking carbonated beverages in the presence of an acid cause the
release of CO2 and make the stomach pH lower, in a manner similar to
Alka-Seltzer, relieving some of the burning associated with Gastric
Refulx or heartburn.

Many of these drugs affect the rate of movement of food through the GI
tract and can cause some problems because of this.

MobiusDick
Kumar - 30 Sep 2005 05:20 GMT
MobiusDick,

Thanks. But I didn't meant that bicarbonate is formed in stomach. When
hcl is formed bicarbonate is released into the blood/body. If hcl is
not formed, body may be deprived of this bicarbonate. Then how it wil
effect?

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