statins and cancer

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fresh~horses - 20 Sep 2005 18:30 GMT

So far the data from large randomized trials is mostly reassuring,
although incomplete.

***The average duration of the trials was 5 years, but most patients
taking stains would expect to do so for life. Cancers can occur after
long latency periods following exposure to the carcinogen, and we do
not yet have the length of follow-up necessary to exclude a
carcinogenic effect of statins.***

The answer will come from epidemiological surveillance and studies with
long-term follow-up.

http://www.jr2.ox.ac.uk/bandolier/booth/cardiac/statcanc.html

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Bill - 20 Sep 2005 19:15 GMT

> So far the data from large randomized trials is mostly reassuring,
> although incomplete.
[quoted text clipped - 9 lines]
>
> http://www.jr2.ox.ac.uk/bandolier/booth/cardiac/statcanc.html

Thanks for the post and being even handed.

Bill

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Jim Chinnis - 20 Sep 2005 21:11 GMT

"fresh~horses" <fresh~horses@despammed.com> wrote in part:

>So far the data from large randomized trials is mostly reassuring,
>although incomplete.
[quoted text clipped - 9 lines]
>
>http://www.jr2.ox.ac.uk/bandolier/booth/cardiac/statcanc.html

There's been at least one study in which the simvastatin and control groups
were reanalyzed 5 or more years after the end of the formal 5-or-so year
study without any difference in cancer rates.

Sorry I don't remember which study this was. It was not as good as a ten
year controlled study, however, since the drug treatment during the 5-or-so
years following the basic study was uncontrolled.
--
Jim Chinnis Warrenton, Virginia, USA

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