Can the brain be segmented chemically?

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fbonsignore@beethoven.com - 05 Aug 2005 19:18 GMT

Is it possible to target different areas in the brain with chemicals
specifically designed to reach those areas and not other areas? For
instance, targeting the Brocca area with some chemical to have some
effect without affecting other cognitive functions? As far as I know,
fat dissolving chemicals will reach the whole brain, not only specific
areas.

If chemical segmentation is possible, different cognitive abilities can
be enhanced/impaired either temporarily or permanently without
affecting the whole behaviour of the individual.

Can somebody point to references?

Fabrizio J Bonsignore now Danilo J Bonsignore

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Barry - 05 Aug 2005 21:26 GMT

Related references:

http://www.dairybusiness.com/northeast/Dec03/F2%20p20%20need%20to%20know%20lep.pdf

"Leptin, which is secreted by adipose (fat) tissue, predominantly
targets regions of the brain involved in the regulation of food intake
and energy metabolism. Leptin also acts on a limited number of
specialized cells, such as those responsible for immunity."

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http://www.mcgees.org/archive/2002_06_01_index.shtml

"Modafinil's...neurological focus is precise, unlike stimulants such as
caffeine and amphetamine. It targets regions of the brain believed to
regulate wakefulness..."

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http://www.path.unimelb.edu.au/research/labs/white/

"Identification of novel drug targets in brain diseases using protein
microarrays...our laboratory is developing protein microarray
technology to identify novel protein drug targets in brain
diseases...with the aim of identifying novel protein-based drug targets
in Parkinson's disease, Creutfeldt-Jakob disease and Alzheimer's
disease."

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