Hunger hormone linked to memory

Scientists have been looking at the hormone that controls hunger
The hormone that controls the body's hunger pangs may also boost the
memory, according to Scottish scientists.

Researchers at Dundee University have found a link between the hormone
leptin and the brain's memory and learning process.

Leptin controls food intake and body weight and staves off the urge to
eat.

The study was carried out by a team which specialises in the braincell
processes that produce learning and memory.

Jenni Harvey, one of the researchers, said: "The hormone leptin, which
is known to control food intake and body weight, has been shown to
exert a profound influence on learning and memory processes in a region
of the brain called the hippocampus.

Gene defects

"Leptin enhances the level of communication between brain cells in the
hippocampus in a process known as long-term potentiation (LTP)."

It has been shown previously that people suffering from obesity have
defects in their leptin levels and in the LTP process.

The group's findings could therefore shed light on how obesity affects
learning and memory.

Dr Harvey said: "Defects in either leptin or genes that regulate leptin
result in obesity and also cause impairments in LTP."

The team is currently examining the precise mechanisms that are
responsible for the effects of leptin on LTP.

The findings are being presented at the annual BioScience conference,
being held in Glasgow until Thursday.

fairuse

http://news.bbc.co.uk/2/hi/uk_news/scotland/4694179.stm