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Medical Forum / General / General / July 2005

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Anemia

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Raphie - 16 Jul 2005 07:18 GMT
Hi everyone!  I have a question that I'm hoping someone might have some
ideas.  First off, I'm a female and I'm 31 years old.  My dad and my
grand dad both had the same surgery I mention next.  I was never obese
to begin with and I do have chronic nausea.  That said, my nausea has
been under control for the last three weeks before I had my iron test
mentioned below done.  Here goes my story....Last July I had a
Vagotomy, Antrectomy and Roux-n-y because I had a 2.5cm bleeding ulcer.
They removed 2/3 of my stomach in order to save my life because I was
bleeding to death.  Anyway, that's all good now except for one thing.
I have developed anemia.  I do take Iron liquid medicine twice per day
and yet my iron is all still low.  I had an Iron Absorption test and
that was fine.  I absorb Iron just fine.  My total iron today was 9,
iron saturation was 3.0, HCT was 33.9, Hemoglobin was 10.9, Ferritin
was 5 and my RDW (or was it RBC?) was abnormal.  I'm guessing that last
one is the shape of the red blood cells.  This is all with eating just
fine and taking Iron liquid form.  I'm always tired and when I'm tired,
I can't just wait to sleep....I have to sleep right then and there.  No
matter what I'm doing.  My doctors are all confused by this and don't
know how to help.  I know there's something going on with me and if I
could just fix this problem, I'd be 100%.  Does anyone have any ideas?

Thanks,
Lisa
ironjustice@aol.com - 16 Jul 2005 17:08 GMT
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David Rind - 16 Jul 2005 19:04 GMT
> Hi everyone!  I have a question that I'm hoping someone might have some
> ideas.  First off, I'm a female and I'm 31 years old.  My dad and my
[quoted text clipped - 19 lines]
> Thanks,
> Lisa

I know this may have come up last year, but were you tested for gluten
intolerance (celiac sprue)?

Signature

David Rind
drind@caregroup.harvard.edu

Sbharris[atsign]ix.netcom.com - 16 Jul 2005 20:29 GMT
> > Hi everyone!  I have a question that I'm hoping someone might have some
> > ideas.  First off, I'm a female and I'm 31 years old.  My dad and my
[quoted text clipped - 26 lines]
> David Rind
> drind@caregroup.harvard.edu

COMMENT:

A good thought, but if this was operating by affecting absorption, then
the absorption test would be off. If (morely likely) it was operating
by causing micro-bleeding, then she should still be quaiac pos (which I
assume has been tested, yes?).

Anyway with a feritin of 5, good absorption, good supplements, guaiac
neg, and no improvement over time, the blood must be going somewhere
intermittantly (rather than oozing, as with sprue). Ulcers usually
don't bleed like that. Occasionally you get a colonic venous
abnormality (AVM) that does.

We need to know a retic count, which will at least insure that the iron
absorbed is being used to make blood.  If that's high, then the new
blood being made can only be going one place. That means guaiac every
stool until you catch it.

SBH
Raphie - 16 Jul 2005 22:17 GMT
Thanks for the post.  I'm going to print all this out and bring it to
my doctor.  The Hematologist also said that I'm probably losing blood
somewhere.  I haven't noticed any blood being lost through the bowel
but sometimes you just don't know.  When I had my bleed last year, it
was all due to the 2.5 cm ulcer.  They found a pool of blood upon entry
with the endoscope.  I also vomitted a lot of it up.  Quite scary.  Are
you suggesting I save all stool until they find it?  Is there such
thing as being able to do the test to see if there's blood in my stool
from home?  I know they've given me the kits but I'd have to mail it in
everytime I go.  There has to be an easier way no?

Thanks!
Lisa
David Rind - 18 Jul 2005 01:39 GMT
>>I know this may have come up last year, but were you tested for gluten
>>intolerance (celiac sprue)?

> COMMENT:
>
> A good thought, but if this was operating by affecting absorption, then
> the absorption test would be off. If (morely likely) it was operating
> by causing micro-bleeding, then she should still be quaiac pos (which I
> assume has been tested, yes?).

Good point. I can't say I've ever heard of an iron absorption test,
though. Do you know anything about its sensitivity?

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David Rind
drind@caregroup.harvard.edu

Raphie - 21 Jul 2005 05:43 GMT
As for the iron absorption test I had, it was done over a few hours.  I
was fasting and they did a baseline.  From there I had to drink a lot
of the pediatric liquid iron supplement.  Then an hour after the Iron
was taken, they drew blood again and then drew it yet again an hour
after that.  That was the extent of my Iron absorption test.  I also
had bloodwork for Pernicious Anemia done.  They checked my Vitamin B12
to check for it.  Is there any other specialized bloodtests that I
should be getting done for the anemia that they might not be thinking
of?

Thanks a bunch guys!
Lisa
David Rind - 22 Jul 2005 02:00 GMT
> As for the iron absorption test I had, it was done over a few hours.  I
> was fasting and they did a baseline.  From there I had to drink a lot
[quoted text clipped - 8 lines]
> Thanks a bunch guys!
> Lisa

It sounds like an iron absorption test -- it's just that I've never seen
 or heard of one being done, and I don't know anything about how well
it predicts actual problems with iron absorption.

By and large the diagnosis of iron deficiency anemia in most situations
is pretty easy -- the blood tests show anemia and low iron levels. At
that point, the cause is either inadequate intake, inadequate
absorption, or blood loss. Most blood loss that causes anemia is pretty
obvious (menstural, gastrointestinal). There are some odd ways to lose
blood (such as in the urine) that can be tested for, but I would guess
that if people are doing an iron absorption test they've already looked
for blood loss. Gastrointestinal blood loss is usually looked for with
repeatedly testing for blood in the stool.

Signature

David Rind
drind@caregroup.harvard.edu

Raphie - 16 Jul 2005 22:13 GMT
Hi there.  Nice to see ya again.  No I haven't been tested for gluten
intolerance.  Can you tell me a bit about that?  Yes, it's been a year
since I've posted.  I'm doing much better than the last time we spoke
except for the anemia.  It's just more of an inconvenience than
anything.  Thanks for the response.
Raphie - 16 Jul 2005 22:30 GMT
I just looked in my medical files and yes I have been tested for gluten
intolerance and I'm fine.  I'll type out the abnormal amounts on this
last bloodwork from this week:  HGB 10.9, HCT 33.9, RDW 18.3, Plt Cnt
434, Lymph Abs 3.6, Total Iron 10, % Saturation 3, Ferritin 6, RBC
Morph Abnormal, Plt Estimate Slt. Inc.  I understand totals except for
Lymph Abs, RBC Morph and the Plt Estimate. Would you believe that my
doctor mailed these test results to me in the mail?  She said to
continue taking my iron as I have been for months.  I just want to
figure this out and get back to normal.  Any tips?

Lisa
Raphie - 21 Jul 2005 06:12 GMT
By the way, I'm not sure if this affects my question but they're also
thinking I have gastric motility.  I guess that comes with the
territory after the surgery I had.  Can it affect my iron?
David Rind - 22 Jul 2005 02:01 GMT
> By the way, I'm not sure if this affects my question but they're also
> thinking I have gastric motility.  I guess that comes with the
> territory after the surgery I had.  Can it affect my iron?

Decreased gastric motility should not affect iron absorption. Decreased
stomach acid from surgery can somewhat decrease iron absorption but not
usually by so much that it can't be overcome by taking iron supplements.

Signature

David Rind
drind@caregroup.harvard.edu

 
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