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Medical Forum / General / General / June 2005how is it that aspirin harms the stomach?
so how is it that aspirin harms the stomach? i mean, isn;t the normal stomach acid about 1000 times stronger than a couple of aspirin sitting there? what am i missing? what is the mechanism? is it because it may come at a time when the stomach has no acid present? doesn;t the stomach lining have to be the same at all times though? is it because aspirin;s acid is different somehow and the stomach only protects against its own acid? wle. > so how is it that aspirin harms the stomach? > [quoted text clipped - 13 lines] > > wle. wie, Some people (especially elderly people) have weak stomachs. Any products that contain acid causes them to get an upset stomach. People that sensitive stomachs (aka weak stomachs) are advised to take aspirin pills and most medications, vitamins and other pills after they eat a meal. You mentioned stomach acid--it's my guess that people that have weak stomachs have a difficult time dealing with normal stomach acids and any extra acids (eg two aspirin pills) cause an upset stomach and in some cases nausea. I knew one elderly person that had to stop drinking diet cokes since they caused him to vomit. He never had those problems when he was a young man. Jason  SignatureNEWSGROUP SUBSCRIBERS MOTTO We respect those subscribers that ask for advice or provide advice. We do NOT respect the subscribers that enjoy criticizing people. >> so how is it that aspirin harms the stomach? >> [quoted text clipped - 26 lines] > young man. > Jason C'mon Jason. I know you love to give medical advice, but shrugging off the poster's question to "old people have weak stomachs" is a pretty half-assed way to explain the effect of aspirin on the stomach. Aren't you going to explain about prostaglandin inhibition and the effect of Cox 1 and 2 ? HMc > >> so how is it that aspirin harms the stomach? > >> [quoted text clipped - 35 lines] > > HMc HMc, You are right--I reread my post and realize that some people such as yourself might now think that I believe that every elderly person in the world has a weak or sensitive stomachs. The truth is that many elderly people have normal stomachs. I did not attempt to explain about prostaglandin inhibition and the effect of Cox 1 and 2 since I know very little about that subject. I am not a doctor or medical expert. Jason SignatureNEWSGROUP SUBSCRIBERS MOTTO We respect those subscribers that ask for advice or provide advice. We do NOT respect the subscribers that enjoy criticizing people. >I did not attempt to explain about >prostaglandin inhibition and the effect of Cox 1 and 2 since I know very >little about that subject. I am not a doctor or medical expert. Maybe there oughta be a lesson in there -- based on this and a battery of posts from you in recent weeks. It's ok to not know something, but if you havent a clue what you are talking about, why not -- with respect but in the vernacular -- keep your mouth shut. I know how tempting it is to want to comment on many things, but a little self-restraint would improve your credibility when you do have something useful/interesting to say. Offering your thoughts, opinions, comments -- that's fine. Providing a continual stream of incorrect information, telling people what to do, and continually appearing to be selling things -- not fine. bob > >I did not attempt to explain about > >prostaglandin inhibition and the effect of Cox 1 and 2 since I know very [quoted text clipped - 14 lines] > > bob bob, You are performing your job as a newsgroup policemen quite well. If all else fails, use words like quack, stupid and ignorant. Instead of helping people, just wait until someone else tries to help them and then go after them. Especially if they mention a vit., mineral or herb that might help them solve a problem instead of a prescribed medication such as Crestor (40 mg) that could eventually cause them to be disabled or actually kill him. Keep up the great work. Jason SignatureNEWSGROUP SUBSCRIBERS MOTTO We respect those subscribers that ask for advice or provide advice. We do NOT respect the subscribers that enjoy criticizing people. "Jason ~ Please do NOT let any lambs Get fleeced ~ ! Merci." ~ Folly >> >I did not attempt to explain about >> >prostaglandin inhibition and the effect of Cox 1 and 2 since I know very [quoted text clipped - 18 lines] >You are performing your job as a newsgroup policemen quite well. If all >else fails, use words like quack, stupid and ignorant. When all else fails, you now must resort to name calling? And you still can't get your facts right. I said absolutely none of those things about you. I even encouraged you to post when you have relevant knowledge or opinion. You continue to maintain a record of posting false information. You also maintain your track record of not responding to factual points. >Instead of helping >people, just wait until someone else tries to help them and then go after >them. When they post factually false stuff, that has to happen. I help people, when I have something useful to say. Facts if I have them, opinions if I want to offer them as such. I probably don't get it all right, and I hope that the wonderful regulars here will correct errors. >Especially if they mention a vit., mineral or herb that might help them >solve a problem instead of a prescribed medication such as Crestor (40 mg) >that could eventually cause them to be disabled or actually kill him. Huh, what has that got to do with the thread? It would help if you would respond to what is said. In another thread, we were discussing something like that. It seems that your preference would be for something that has not even been tested, so we do not know what benefits or hazards it might have. You failed on repeated requests to provide any relevant facts. People who bask in their ignorance are not helping others here. Hm, you omitted your sig this time. Maybe that is progress. The first time I saw it, I wondered what kind of person would use that sig. It seemed to be an announcement that you _intended_ to post garbage, and would criticize anyone who tried to shed some light on the matter. Right on! bob >Some people (especially elderly people) have weak stomachs. What the hell is a weak stomach? >>Some people (especially elderly people) have weak stomachs. > >What the hell is a weak stomach? One that hasn't been doing enuff time in the gym? Kurt ( I want to (proton) pump you up) Ullman ---- Ideologue: noun. Someone who disagrees with the writer on an issue and is insufficiently apologetic about it. Stolen from Billo in misc.writing ~~~~~~~~~~~~~~~~~~~~~~~ A few days ago I composed a good reply only to have it kicked out for SERVER ERROR. I appreciate the info that coatings don't work, because I have known that for decades. My stomach can stand only the 80 MG aspirin dose twice a week. To prevent bloating and pain from the concentrated acetyl salicilate, I make a powder of a Bayer belly burner and ingest it with food or beverage, even coffee. Even these small amounts of aspirin are like a wonder drug. They quickly relieve nonexertional angina as well as promote bowel movements. They also improve the quality of sleep. David H ~~~~~~~~~~~~~~~~~~~~~~~~~ >so how is it that aspirin harms the stomach? > >i mean, isn;t the normal stomach acid about 1000 times stronger than a >couple of aspirin sitting there? You're right on. In addition, aspirin is a very weak acid (high pKa, if you have had some chemistry), so it really is not acidic at all in the stomach. Aspirin works thru physiology. Have you heard of COX-II inhibitors, such as Vioxx -- much in the news over recent months? The idea is that Aspirin inhibits an enzyme called COX. But there are multiple COX enzymes. Inhibiting one of them reduces inflammation; inhibiting another can cause stomach bleeding. The idea was that a COX-II inhibitor would do only one of those two things. Of course, the story turns out to be more complex, but it gives the idea of how aspirin works via physiology, not directly thru its acidity. bob > You're right on. In addition, aspirin is a very weak > acid (high pKa, if you have had some chemistry), so it > really is not acidic at all in the stomach. > Aspirin works thru physiology. Have you heard of COX-II > inhibitors, such as Vioxx -- much in the news over [quoted text clipped - 6 lines] > it gives the idea of how aspirin works via physiology, > not directly thru its acidity. Yep. Which further explains why enteric-coated aspirin is no better than plain. The effect is systemic, not contact. |
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