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Medical Forum / General / General / May 2005Question about Latent Conditions- TB, Cancer
Hello, I want to understand following aspect:- Suppose a person is exposed to TB bacterias & gets some passing acute reactions but didn't get it as full active stage. So he aquires latent TB infections with out any symptoms. I think it is due to inability of immunity to handle all the bacterias on its exposure at that time. Our defence system then opt for 2nd option--arrest/encapsule these bacterias as latent stage to stop their multiplication & spread or starve these in capsule by arresting or wait for the right oppurtunity by improving the immunity/defence power to kill them. Is it right? Now suppose that person gets his immunity/defence power suitably improved after some time to handle those hidden/dormant or encapsuled bacterias OR weakens it. What will happen? On improving the immunity--will those bacterias be resurfaced/directly exposed to immune agents to kill them as a "direction towards cure" & presenting an apparent impression of active stage OR not? On weakenung the immunity--will these infecting agents be resurfaced, multiply & spread as a "direction towards spread of disease" OR not? Same can be thought about cancer. In short; can impression of active stage/spread after a latency/tumor formation be a direction towards cure on improved immunity AND a direction towards increase in infection/disease on weakening of immunity/defence power? Best regards. Sorry, I have one more question:- Whether excess/low gastric acid can cause the effectiveness of DOTS- TB durgs? A person under this TB tratment if lives in a place with hard water/alkaline water supply OR take other foods which can raise his gastric pH, can get lesser effects of TB medicines or not? In short, I want to know whether digetive pH can effect the effectiveness of TB medicines or not? Can low pH also encourage intestine mucus blocks resulting into low medicines absorption? > Sorry, I have one more question:- > [quoted text clipped - 7 lines] > Can low pH also encourage intestine mucus blocks resulting into low > medicines absorption? Hello, I am sorry but I don't know the answer. You should ask your doctor these questions. If you live in an area that has hard water--consider buying filtered water to drink. In addition, visit this site. They have a "Home test pH kit" for sale. It comes with a booklet that explains the pH levels of various foods. It also explains how to test the pH of your urine which means that you would always know your current pH level. The kit contains everything you need to conduct the tests. www.feelgoodfood.com phone 1-630-355-7746  SignatureNEWSGROUP SUBSCRIBERS MOTTO We respect those subscribers that ask for advice or provide advice. We do NOT respect the subscribers that enjoy criticizing people. Jason, thanks for reply. But I will require/consider to do pH testing when I shall know that pH of water or our digestive system can effect effectiveness of TB durgs. Frankly, it looks that durgs are not working properly in patient, as she is not feeling any side/adverse effects, acidity etc. even after 2 months of durgs taking. Doctors just say it is normal but I just suspect & want to clear because it can be an unattended aspect as yet in view of my above considerations. So pls think deeply & dynamically & comment(without commitment). >Jason, thanks for reply. But I will require/consider to do pH testing >when I shall know that pH of water or our digestive system can effect [quoted text clipped - 4 lines] >unattended aspect as yet in view of my above considerations. So pls >think deeply & dynamically & comment(without commitment). Please don't take Jason's advice on anything. He has repeatedly shown his basic ignorance about most medical issues, and is impervious to requests that he not speak with the illusion of authority on topics on which he is ill-informed. Lately he's gotten into some pseudoscience about pH, and efforts to correct him have been futile. I hope that someone knowledgable about the treatment of infectious disease, e.g. Dr. Rind, will answer your questions. Your friend's doctors certainly know more about her case, and about treating people with your local strains of TB than anyone who is likely to reply to you here. I'm not a doctor, but I would think that a lack of side effects or adverse effects in your friend is a good thing, and not a sign of ineffectiveness. Also, AFAIK, drug treatment for TB can take a long time, so two months may be too soon for benefit to become clearly apparent. No doubt it depends on the drug, the patient and the strain of TB. Again, I'm speaking from ignorance, but at least I admit it. > Jason, thanks for reply. But I will require/consider to do pH testing > when I shall know that pH of water or our digestive system can effect [quoted text clipped - 4 lines] > unattended aspect as yet in view of my above considerations. So pls > think deeply & dynamically & comment(without commitment). You may want to re-read the printouts that came with the medications. In many cases, there are instuctions as to when to take the medications. It may state that you should take the medications with food or on an empty stomach. If so, make sure that those instuctions are followed. I should state that I am NOT a doctor. Thanks for a professional response. SignatureNEWSGROUP SUBSCRIBERS MOTTO We respect those subscribers that ask for advice or provide advice. We do NOT respect the subscribers that enjoy criticizing people. Thanks, It is indicated as durg interaction that many antacids can reduce the effect of one out of four TB drug- INH. I couldn't find this against other 3 drugs so not sure about it. Does it not tells that low gastric acid due to some other reasons as hard/alkaline water can lower the effectiveness of INH? > Thanks, It is indicated as durg interaction that many antacids can > reduce the effect of one out of four TB drug- INH. I couldn't find this > against other 3 drugs so not sure about it. Does it not tells that low > gastric acid due to some other reasons as hard/alkaline water can lower > the effectiveness of INH? That's an interesting question. You should ask a doctor or nurse about this issue. SignatureNEWSGROUP SUBSCRIBERS MOTTO We respect those subscribers that ask for advice or provide advice. We do NOT respect the subscribers that enjoy criticizing people. > > Thanks, It is indicated as durg interaction that many antacids can > > reduce the effect of one out of four TB drug- INH. I couldn't find this [quoted text clipped - 4 lines] > That's an interesting question. You should ask a doctor or nurse about > this issue. I was able to find a newsgroup that you may be able use to find an answer to your question: sci.med.pharmacy also: try this one: sci.med.pathology SignatureNEWSGROUP SUBSCRIBERS MOTTO We respect those subscribers that ask for advice or provide advice. We do NOT respect the subscribers that enjoy criticizing people. Jason. thanks for suggestions. Btw whether all prescribers shouldn't know this type of conepts? Should we be prescribed only after a prescriber has complete knowledge of durg just equal to the research scientist who made that durg have? "M. tuberculosis was the most restricted in growth at pH 6.0, and all of this growth required elevated levels of Mg2+...These results demonstrate that M. tuberculosis is unique among the mycobacteria in its extreme sensitivity to acid and indicate that M. tuberculosis must acquire sufficient Mg2+ in order to grow in a mildly acidic environment such as within the phagosome of macrophages. http://iai.asm.org/cgi/content/abst...pe2=tf_ipsecsha " Does it indicate awnser to my sceond question? > Jason. thanks for suggestions. Btw whether all prescribers shouldn't > know this type of conepts? Should we be prescribed only after a [quoted text clipped - 9 lines] > http://iai.asm.org/cgi/content/abst...pe2=tf_ipsecsha " > Does it indicate awnser to my sceond question? That's an interesting question. Please copy and paste the above information and post it in this newsgroup: sci.med.pharmacy SignatureNEWSGROUP SUBSCRIBERS MOTTO We respect those subscribers that ask for advice or provide advice. We do NOT respect the subscribers that enjoy criticizing people.
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