Buspar & trazadone

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silver_1@mindspring.com - 28 Apr 2005 01:21 GMT

I have read that the combination of Buspar (buspirone) and
trazadone can cause serious liver problems.
My question is: At what strengths? For example, would it be dangerous
to take ~15 mg/day of buspirone
(for anxiety) and 100 mg of trazadone (as an aid to sleep)?
I have asked my doctor and received an equivocal answer. My
pharmacist simply doesn't know. I
have been unable to get specific dose-related information on the
Internet.

I would be truly grateful to hear from a knowledgeable person
about this concern I have.

Could you please also reply directly to me at:
silver_1@mindspring.com?

Thanks in advance for any help you can provide.

Charlie Silver

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Emma Chase VanCott - 28 Apr 2005 14:37 GMT

: I have read that the combination of Buspar (buspirone) and
: trazadone can cause serious liver problems.
: My question is: At what strengths? For example, would it be dangerous
: to take ~15 mg/day of buspirone
: (for anxiety) and 100 mg of trazadone (as an aid to sleep)?

The gold standard for treating anxiety is Paxil.

BuSpar has never been a first line treatment, nor is it terribly
effective, as i recall.

If you have sleep problems, you really ought to have a sleep study done.
Pills only cover up problems.

How much vigorous exercise are you getting? This is the best treatment for
anxiety/depression _and_ sleep problems.

Emma

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REP - 29 Apr 2005 06:33 GMT

> : I have read that the combination of Buspar (buspirone) and
> : trazadone can cause serious liver problems.
[quoted text clipped - 6 lines]
> BuSpar has never been a first line treatment, nor is it terribly
> effective, as i recall.

It works in benzodiazapam-naive patients.

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"Did Father shoot him? I will eat Grandfather for dinner."
- Helen Keller, on learning of the death of her grandfather

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rastapasta - 28 Apr 2005 19:18 GMT

> I have read that the combination of Buspar (buspirone) and
> trazadone can cause serious liver problems.
[quoted text clipped - 15 lines]
>
> Charlie Silver

IMO, Buspar sucks. I've said this in other NG's, but I actually got some $$
out of a class-action lawsuit against them:
http://www.prescription-drugs-lawsuits.com/buspar.htm

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