Medical Forum / General / General / March 2005
Do cola and diet drinks cause diabetes ?
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habshi - 27 Feb 2005 21:40 GMT Maybe they destroy the pancreas beta cells , they are certainly toxic to teeth. Might be interesting to test on mice by feeding them cola and diet drinks every day and seeing if they get fat . Maybe the body is expecting high sugar from the diet additive and insulin secretion increases . Insulin resistance is the biggest problem today . These type 2 diabetics have higher than normal insulin initially but the body muscle is resistant to it , could be cola and diet sugar additives block the receptors.
ranolki - 27 Feb 2005 18:12 GMT > Might be interesting to test on mice by > feeding them cola and diet drinks every day and seeing if they get fat Far more interesting to test them on habshis...under strict laboratory conditions, of course.
cheers ranolki
Jeff - 27 Feb 2005 23:47 GMT > Maybe they destroy the pancreas beta cells , they are > certainly toxic to teeth. Might be interesting to test on mice by [quoted text clipped - 5 lines] > initially but the body muscle is resistant to it , could be cola and > diet sugar additives block the receptors. No, it couldn't be. It is a metabolic disease that is either brought by or made worse by being too fat and not getting enough excercise.
Jeff
tech27 - 28 Feb 2005 04:36 GMT > Maybe they destroy the pancreas beta cells , they are > certainly toxic to teeth. Yup. That's why you should brush your pancreas twice a day.
Might be interesting to test on mice by
> feeding them cola and diet drinks every day and seeing if they get fat Might be interesting for you to not subject us to your stupid, uniformed speculations.
> . > Maybe the body is expecting high sugar from the diet additive > and insulin secretion increases. The body only expects food and water. Do you know if the body was expecting diet Coke or Pepsi?
Insulin resistance is the biggest
> problem today . These type 2 diabetics have higher than normal insulin > initially but the body muscle is resistant to it , could be cola and > diet sugar additives block the receptors. Are you making this up as you type? Type 2 diabetics ARE type 2 BECAUSE their pancreas doesn't produce ANY insulin, that's why they have to inject. "Insulin Resistance" refers to the body's resistance to injected insulin. Was worse with beef and pork insulin, but not as bad with DNA synthesised insulins.
habshi - 28 Feb 2005 17:49 GMT >Are you making this up as you type? Type 2 diabetics ARE type 2 BECAUSE their pancreas doesn't produce ANY insulin,<
That's type 1 , you fool . Type 2s have too much insulin initially
tech27 - 28 Feb 2005 20:20 GMT >>Are you making this up as you type? Type 2 diabetics ARE type 2 BECAUSE > their pancreas doesn't produce ANY insulin,< > > That's type 1 , you fool . Type 2s have too much insulin initially Of course, me stupid. Probably low blood sugar at time of posting. As a diabetic (Type 1) I've never run across the idea that type 2s have too much insulin initially. Most type 2's are treated to try and reduce the need for insulin, such as diet, exercise, and most importantly in this discussion, with oral medications like Digliburide (sp?) which serve to stimulate insulin production. I was able to stabilize on this for about 6 months then had to go do injections. Could you please point me to some sources which discuss this "too much insulin initially" thing?
Thanks
habshi - 28 Feb 2005 21:00 GMT Lack of excercise leads to insulin resistance . Do a google search and type 'excess insulin in type 2 diabetes'
Genetics play a large role in type 2 diabetes and family history is a risk factor. However, low activity level, poor diet, and excess body weight (especially around the waist) significantly increase your risk for type 2 diabetes.
http://www.reutershealth.com/wellconnected/doc60.html Type 2 Diabetes
Type 2 diabetes is most common form of diabetes, accounting for 90% of cases. An estimated 16 million Americans have type 2 diabetes and half are unaware they have it. The disease mechanisms in type 2 diabetes are not wholly known, but some experts suggest that it may involve the following three stages in most patients:
The first stage in type 2 diabetes is the condition called insulin resistance; although insulin can attach normally to receptors on liver and muscle cells, certain mechanisms prevent insulin from moving glucose (blood sugar) into these cells where it can be used. Most type 2 diabetics produce variable, even normal or high, amounts of insulin, and in the beginning this amount is usually sufficient to overcome such resistance.
Over time, the pancreas becomes unable to produce enough insulin to overcome resistance. In type 2 diabetes the initial effect of this stage is usually an abnormal rise in blood sugar right after a meal (called postprandial hyperglycemia ). This effect is now believed to be particularly damaging to the body.
Eventually, the cycle of elevated glucose further impairs and possibly destroys beta cells, thereby stopping insulin production completely and causing full-blown diabetes. This is made evident by fasting hyperglycemia , in which elevated glucose levels are present most of the time
Dandapani Sahu - 28 Feb 2005 21:24 GMT > >>Are you making this up as you type? Type 2 diabetics ARE type 2 BECAUSE > > their pancreas doesn't produce ANY insulin,< [quoted text clipped - 13 lines] > > Thanks Type II patients don't have too much insulin initially or don't have too much insulin producing capacity.
However, its true that Type II patients have generally too much insulin in their system. The body keep producing insulin as the sugar level in blood is high. But, the body being resistant to insulin, can't utilize the insulin.
Sooner or later, if proper diet, weightloss plan, and medicine are not followed, the body stops producing insulin and the type II patiert has to depend on injected insulin in addition to other medicine like metformin.
Type II patients must reduce weight, must follow diet, must do exercise in addition to medication. Intially, weight loss will help a lot. Doctors recomend 10% weight loss when they determine insulin resistance.
Thanks bud.
DS
tech27 - 01 Mar 2005 14:43 GMT > Type II patients don't have too much insulin initially or don't have too > much insulin producing capacity. Thank you. I was sure the OP was incorrect. Although I did go through a period of oral meds, it didn't really help. In my case I was perfectly normal (well, physically anyway), (-; and got severe food poisoning. I was unconscious for almost 2 days, sweating profusely and with a high fever. When I normalized, I could tell in a few days that I could be the poster child for symptoms of diabetes.
oldal4865 - 01 Mar 2005 15:10 GMT tech27 wrote in message ...
>>>Are you making this up as you type? Type 2 diabetics ARE type 2 BECAUSE >> their pancreas doesn't produce ANY insulin,< [quoted text clipped - 13 lines] > >Thanks A statistically average Type 2 diabetic will have lost about 50% of his self-generated insulin capacity at the time of diagnosis. However, since the average person has a huge excess of insulin capacity, the newly diagnosed Type 2 still can and probably will produce more insulin than the average person would need to get through a day. Of course, the Type 2 usually exhibits high Insulin Resistance so even though he is producing more than a normal person would need, he still isn't making enough to control his blood glucose.
Type 2 diabetes is a genetic disease. It can develop fast enough to send your blood glucose out of control at age 15, or age 30, or age 60 or age 90. Lifestyle tends to control when the sugars go out of control. High levels of abdominal fat and a sedentary lifestyle bring it on earlier. Live a "40 acres and a mule" lifestyle, and you may die from old age before losing control of your sugar.
For a scary look at the disease, and probably more than you want to know about it, see:
"The Progression and Natural History of Type 2 Diabetes"
A very good speech to doctors by an Endo, given at the 2001 ADA convention, presented at the URL shown below.
http://www.medscape.com/viewprogram/145
When you get to the site, select ?The Progression and Natural History of Type 2 Diabetes? in the table of contents. .
Note the extrapolation on Slide 10 which indicates that damage to beta cells from high Insulin Resistance starts 10 years before diagnosis and the average T2 has lost about 50% of his beta cells at time of diagnosis.
Your question about "too much insulin" is answered by Slide 6. "endogenous insulin" curve)
Regards Old Al
habshi - 01 Mar 2005 18:07 GMT Once a diagnosis is made how many people manage to stay off drugs by controlling weight and diet?
Dandapani Sahu - 01 Mar 2005 19:57 GMT Not forever. They may avoid medication for a few years, but sooner or later they must take medicine. And, all along, they must be following a diet plan and regular exercise..
But, coming back to the original subject, cola even if it is diet and low calorie should be avoided by all. Not sure if there is a study of insulin level before and after drinking 2 cans of diet soda.
If body and mind can be fooled by simple suggestion to placibos, why can't it be fooled by sweet diet drinks???
Thanks bud.
DS
> Once a diagnosis is made how many people manage to stay off drugs by controlling weight and > diet? tech27 - 03 Mar 2005 05:29 GMT ..
> But, coming back to the original subject, cola even if it is diet and low > calorie should be avoided by all. Not sure if there is a study of insulin > level before and after drinking 2 cans of diet soda. It's not really measurable. The beauty of the system is that insulin is produced exactly when needed and in the amount needed. The latency is almost immesureable.
> If body and mind can be fooled by simple suggestion to placibos, why can't > it be fooled by sweet diet drinks??? I assume you mean "placebo". What do you mean "fooled" by sweet drinks? Fooled how? Pepsi or Coke?
> Thanks bud. > [quoted text clipped - 3 lines] > controlling weight and >> diet? oldal4865 - 01 Mar 2005 20:49 GMT > Once a diagnosis is made how many people manage to stay off drugs by controlling weight and >diet? That's an unknown quantity. Diabetes statistics aren't that good.
However, there's another point to ponder. Most of the better drugs have pronounced anti-heart attack properties for diabetics and it turns out that Type 2 diabetes can be considered more of a cardiovascular disease than a "blood sugar control disease", e.g.
". . .For most of my patients, diabetes is really a cardiovascular disease, occasionally complicated by high blood sugar. . ."
Diabetes Forecast, September 2001
A newly diagnosed Type 2 usually has a lousy lipid panel with high triglycerides most apparent. Those lousy lipids have been attacking his arteries for years before anybody usually notices. The better Diabetes meds, metformin and Actos/Avandia, tend to reverse Insulin Resistance and thus improve the lipids.
Metformin has cut the premature death rate by 30-40% in clinical trials.
(UK Prospective Diabetes Study (UKPDS) Group. Lancet 1998 Sep 12;352(9131):854-65)
Blood pressure often creeps up into a danger zone (130/85, sorta OK for normies, not for diabetics) at the same time.
Often you can do the same job with lifestyle instead of meds but it's very hard and takes a lot longer with your arteries under siege all the while. Moreover, simple blood sugar control is not the only criterion. You need to reduce your circulating insulin concentrations and do a really good job on lipids. (When normies aimed for LDL less than 130, Type 2 diabetics aimed for less than 100)
One strategy: If lifestyle helps, and meds help, "do both."
A Type 2 lifestyle approach calls for the diabetic to:
a. Lose fat, especially abdominal and omental fat b. Gain muscle lb. anyway he can c. Exercise every day d. Ration his daily carb, eat slowly-digesting carb, spread his daily carb over several small meals.
Ummm. . .if you have blood relatives with Type 2 diabetes, odds are that you have some of the genes. Items a, b, c and d should be an integral part of your life lest you be drafted into our Club. . .the Club nobody wants to join.
Regards Old Al
tech27 - 03 Mar 2005 05:33 GMT >> Once a diagnosis is made how many people manage to stay off drugs by > controlling weight and >>diet? > > That's an unknown quantity. Diabetes statistics aren't that good. Where do you live? Sierra Leone? There are mountains of stats on exactly that issue. Go find them before you spout off, lazy f.ck.
> However, there's another point to ponder. Most of the better drugs > have [quoted text clipped - 8 lines] > > Diabetes Forecast, September 2001 That's not the point you moron. Diabetes has serious complications for heart, kidney, eysight, nerous system, etc. The comment was not meant to be taken literally, except by idiots who are too dim to know the difference.
Old Al
Old, stupid, uniformed, Al.
oldal4865 - 03 Mar 2005 16:39 GMT tech27 wrote in message ...
>That's not the point you moron. Diabetes has serious complications for >heart, kidney, eysight, nerous system, etc. The comment was not meant to be [quoted text clipped - 3 lines] > >Old, stupid, uniformed, Al. That comment was meant to be taken literally. The doctor made a big deal out of it.
You need to take a look at your non-life:
1. Go back to high school, try for a degree. If not, try for a GED
2. Go back to the psychiatrist; apologize, start taking the meds again.
PLONK
tech27 - 03 Mar 2005 18:03 GMT > tech27 wrote in message ... >> [quoted text clipped - 9 lines] > That comment was meant to be taken literally. The doctor made a big > deal out of it. Then the doctor is an idiot. That's like saying cigarettes are a disease of the lungs. They CAUSE the disease, they are not THE disease. A basic grasp of english should be a prerequisite of any medical training.
> You need to take a look at your non-life: > [quoted text clipped - 5 lines] > > PLONK Easy old boy, don't want to have to double up on the hypertensive meds.
tech27 - 03 Mar 2005 05:25 GMT > Once a diagnosis is made how many people manage to stay off drugs by > controlling weight and > diet? I thought you knew all the answers? Don't waste our time here. Go google diabetes and oral medication and see the results.
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