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Medical Forum / General / General / February 2005tPA Window of time
tPA is use as a clot dissolver in the advent of a stroke. However there is a window of time (3 hours) that it can be used effectively, as I understand. Why is there this time constraint? Thanks. Don W "Donald Wilgus" <dwilgus@prodigy.net> wrote in part: > tPA is use as a clot dissolver in the advent of a stroke. However there >is a window of time (3 hours) that it can be used effectively, as I >understand. Why is there this time constraint? Because the clot cuts off much of the blood supply to neurons and other cells in the affected region of the brain and after a while they die. Although this pretty effective treatment (and other similar ones) has been around for quite some time, few hospitals seem to offer it. -- Jim Chinnis Warrenton, Virginia, USA jchinnis@alum.mit.edu JIm, After 3 hours, they do not want to use tPA. And even under imaging, if they can't see the clot, they don't want to use it. (To my understanding). Why? It would seem that if they had established that it was not a hemorrhaging type of stroke, they would just go ahead and use it for the insurance. I understand the side effects of tPA are not nice. Does that prevail? Thanks. DonW > "Donald Wilgus" <dwilgus@prodigy.net> wrote in part: > [quoted text clipped - 9 lines] > -- > Jim Chinnis Warrenton, Virginia, USA jchinnis@alum.mit.edu ...or maybe after 3 hours they figure all the damage that can be done is done, so why bother taking the risk with tPA. > "Donald Wilgus" <dwilgus@prodigy.net> wrote in part: > [quoted text clipped - 9 lines] > -- > Jim Chinnis Warrenton, Virginia, USA jchinnis@alum.mit.edu Bingo. "Donald Wilgus" <dwilgus@prodigy.net> wrote in part: >...or maybe after 3 hours they figure all the damage that can be done is >done, so why bother taking the risk with tPA. [quoted text clipped - 14 lines] >> -- >> Jim Chinnis Warrenton, Virginia, USA jchinnis@alum.mit.edu -- Jim Chinnis Warrenton, Virginia, USA jchinnis@alum.mit.edu > tPA is use as a clot dissolver in the advent of a stroke. However there > is a window of time (3 hours) that it can be used effectively, as I [quoted text clipped - 3 lines] > > Don W The brain cells have already had too much ischemia and are dead by 3 hours, Tpa would do no good. They also can not give it until they have rulled out the 10% chance that it is a hemmoragic stroke (aneurysm) as opposed to a thromibic. -- Patrick H. Mason M.S. OHST, EMT-I |
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