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Medical Forum / General / General / January 2005Paternity & Blood Type
I know that blood types don't in any way provide a definitive test for paternity but is there any way for two type O people (one Rh+ the other neg) to produce a child who is not type O? > I know that blood types don't in any way provide a definitive test for > paternity but is there any way for two type O people (one Rh+ the other neg) > to produce a child who is not type O? No. Two People with O blood will be allele OO, they have sort of blank blood, so they can only pass an O onto their children. If the child is A or B then one of the parents would need to be either an A or B to pass that allele on. Andrea > I know that blood types don't in any way provide a definitive test for > paternity but is there any way for two type O people (one Rh+ the other neg) > to produce a child who is not type O? No. Because type O is recessive, the only way to have an O phenotype is to have an OO genotype. That means that neither parent has A or B antigens to pass on to the child. Best wishes, Ericka > No. Because type O is recessive, the only way to have an >O phenotype is to have an OO genotype. That means that neither >parent has A or B antigens to pass on to the child. Okay, it is early in the morning. I haven't had my coffee yet. So I may be mis-reading this. My mother has O- blood. My father has B+ blood. My sister is B-, and I am O+. Unless I have misunderstood, there is no way that neither me nor my sister should have the blood types that we do, and yes, the B+ father is our real, biological father. Please, help me and use words that my almost 4 year old could understand... thanks. -- Daye Mommy to DD3 and DS1 Chump Change for Major Change http://www.change4change.tk *On Mon, 10 Jan 2005 21:58:15 -0500, Ericka Kammerer <eek@comcast.net> *wrote: * *> No. Because type O is recessive, the only way to have an *>O phenotype is to have an OO genotype. That means that neither *>parent has A or B antigens to pass on to the child. * *Okay, it is early in the morning. I haven't had my coffee yet. So I *may be mis-reading this. * *My mother has O- blood. My father has B+ blood. My sister is B-, and *I am O+. OK, so as Ericka stated, the only way to have an O phenotype is to have an OO genotype. You and mom both have OO. You got one O from mom, and one O from dad. Now, dad is phenotypically B, but you are his offspring and you are O, so his genotype has to be BO (or OB if you prefer :)). Your sister got a B from him to go along with the O she got from mom. The Rh factor is a whole separate issue. *Unless I have misunderstood, there is no way that neither me nor my *sister should have the blood types that we do, and yes, the B+ father *is our real, biological father. Does it make sense now?  SignatureHillary Israeli, VMD Lafayette Hill/PA/USA/Earth "Outside of a dog, a book is a man's best friend. Inside of a dog, it is too dark to read." --Groucho Marx > * > *My mother has O- blood. My father has B+ blood. My sister is B-, and > *I am O+. > The Rh factor is a whole separate issue. so you mum is --, as - is recessive, as your sister is - you know your dad must be +- as he passed - on to your sister, you got the + from your dad along with a - from your mum, making you +, but with a - gene as well, so if your hubbie is - or a - carrier you could produce - children. >> No. Because type O is recessive, the only way to have an >>O phenotype is to have an OO genotype. That means that neither [quoted text clipped - 12 lines] > Please, help me and use words that my almost 4 year old could > understand... thanks. No, your situation is perfectly fine. What you know is that your mother is OO-- (expressing O-) and your father is BO+- (expressing B+). Your sister got an O- from your mother and a B- from your father. You got an O- from your mother and an O+ from your father. Best wishes, Ericka >I know that blood types don't in any way provide a definitive test for >paternity but is there any way for two type O people (one Rh+ the other >neg) to produce a child who is not type O? Nope. Not if all the typing is accurate. Jenrose > I know that blood types don't in any way provide a definitive test for > paternity but is there any way for two type O people (one Rh+ the other neg) > to produce a child who is not type O? Despite all the answers you got to the negative the answer is that it is rarely possible for two individuals who appears to be type O to have a child who is not type O. Google "Bombay phenotype". SignatureDavid Rind drind@caregroup.harvard.edu >> I know that blood types don't in any way provide a definitive test for >> paternity but is there any way for two type O people (one Rh+ the [quoted text clipped - 3 lines] > rarely possible for two individuals who appears to be type O to have a > child who is not type O. Google "Bombay phenotype". Hmmm...I don't think it actually works that way. If the *parents* appeared to be type O because they were hh, then the child would, of necessity, be hh as well, so regardless of where the child was on the ABO type, the child would still present as O due to being hh. Best wishes, Ericka >> Despite all the answers you got to the negative the answer is that it is >> rarely possible for two individuals who appears to be type O to have a [quoted text clipped - 5 lines] > of where the child was on the ABO type, the child would > still present as O due to being hh. yeah, my understanding of this is it produces the opposite effect, when one parents is AB and therefore cannot pass on the O, you can actually get an O child, if there are also hh. Opposite to what the original poster was asking, but interesting nontheless. In article <HeSdnd55HYOkxH7cRVn-jA@comcast.com>, Ericka Kammerer <eek@comcast.net U> wrote: >>> I know that blood types don't in any way provide a definitive test for >>> paternity but is there any way for two type O people (one Rh+ the [quoted text clipped - 9 lines] >of where the child was on the ABO type, the child would >still present as O due to being hh. No. Assume one parent is a "real" type O (Hh or HH). The other parent has some other ABO type masked by being hh. The child gets H and O from the type O parent, and h and A or B from the hh parent. Voila, child with type A or B, normally expressed due to Hh, from parents who appear to be both type O. Incidentally, there are a few even rarer conditions that can produce this apparent mismatch, but as we've seen on this newsgroup before, people often only *think* they know their blood type. Since paternity can be such an emotional and personally destructive issue, there's a lot to be said for giving everybody the benefit of the doubt in the absence of really reliable data. > In article <HeSdnd55HYOkxH7cRVn-jA@comcast.com>, > Ericka Kammerer <eek@comcast.net > U> wrote: >>>Despite all the answers you got to the negative the answer is that it is >>>rarely possible for two individuals who appears to be type O to have a [quoted text clipped - 11 lines] > child with type A or B, normally expressed due to Hh, from parents who > appear to be both type O. Okay, I'll buy that--forgot to consider the mixed parent scenario ;-) > Incidentally, there are a few even rarer conditions that can produce > this apparent mismatch, but as we've seen on this newsgroup before, > people often only *think* they know their blood type. Since paternity > can be such an emotional and personally destructive issue, there's a > lot to be said for giving everybody the benefit of the doubt in the > absence of really reliable data. I would absolutely agree with that--and, in fact, I would imagine that lab mixups and misremembering blood types are probably quite a bit more likely than the Bombay phenotype scenario (or the other even rarer scenarios). If the OP is concerned about a real life paternity issue rather than a theoretical argument, then it would far and away be wisest not to take any action or make any assumptions until and unless reliable testing has produced clear results. A scenario with two type O parents and a non-O child should raise a big red flag requiring some further investigation, but it hadn't occured to me that anyone would assume such information as conclusive regarding paternity. Best wishes, Ericka |
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