Seems like a long time ago of perhaps 6 months that I discussed Prion
disease. Partly because there was no new news. There was great news on
my theory that Prion disease is a family related disease to Alzheimers
and Parkinsons. And it was recently found (in 2004) that Parkinsons is
caused by bacteria and fungus in well-water. My theory of Family Related
Diseases then implies that Alzheimers and Prion thus have a link to
bacteria and fungus as causative agents. Somehow, bacteria and fungus
spur the onslaught of Alzheimers and Prion and may, like in Parkinsons,
be a sole cause for Prion disease.
One of the reasons I bring up Prion disease today is word that a new Mad
Cow was found in Canada in recent days.
Canada is abundant in Parkinsons disease and Canada has a lot of well
water. England seems to be the most abundant for Mad Cow disease. And
England has a lot of well water for cattle drinking. Can someone say
whether bacteria and fungus have geographical best zones of habitat? I
mean, do some bacteria and fungus live better in England and Canada than
say mainland Europe or USA?
So why is Canada so abundant for Mad Cow Disease, more so than the USA
and factoring in that Canada has so sparse a density of cows and people
compared to USA.
So my theory of Prion disease is that it is a Family Related Disease to
Alzheimers and Parkinsons. So if Parkinsons is denser in Canada than
USA, then prion of Mad Cow should be denser in Canada than USA. And that
Prion disease is not what the Prusiner Model tells us of a rogue protein
causing agent but rather instead the causing agent is bacteria and
fungus.
When a group of diseases is packaged into a Family-Related-Diseases,
then what causes one disease of that family pretty much causes the
disease in the other members of that family group of diseases. So when
bacteria and fungus cause Parkinsons, then bacteria and fungus are the
prime causes of Prion disease.
And that is why Canada has a higher incidence of both Prion and
Parkinsons disease is because some types of bacteria and fungus live
better in Canada.
And as for the Prusiner Model of prion disease, well, I expect any news
supporting that model to continually wane and then disappear because it
is a fake model of the reality of what is truly going on. And more and
more news of bacteria and fungus as the causative agent of Prion
diseases and Parkinsons and even likely cause Alzheimers.
Archimedes Plutonium
www.iw.net/~a_plutonium
whole entire Universe is just one big atom where dots
of the electron-dot-cloud are galaxies
Chuck R. - 02 Jan 2005 06:21 GMT
BULL.....Apparently you have never been on a farm or feed lot.. Virtually
all are in the country and must utilize well water as their water source,
including for the owners and employees. Your assumption holds "No Water"
Chuck
> Seems like a long time ago of perhaps 6 months that I discussed Prion
> disease. Partly because there was no new news. There was great news on
[quoted text clipped - 47 lines]
> whole entire Universe is just one big atom where dots
> of the electron-dot-cloud are galaxies
Steve Turner - 02 Jan 2005 14:43 GMT
>BULL.....Apparently you have never been on a farm or feed lot.. Virtually
>all are in the country and must utilize well water as their water source,
>including for the owners and employees. Your assumption holds "No Water"
AP does not care about empirical data. That is where his own brand of
"scientific method" slips gears -- he does not test his hypotheses
against available data, and/or he ignores anything which does not
support his hypothesis. Not very scientific, eh?
Steve Turner
Archimedes Plutonium - 03 Jan 2005 06:44 GMT
> So my theory of Prion disease is that it is a Family Related Disease to
> Alzheimers and Parkinsons. So if Parkinsons is denser in Canada than
[quoted text clipped - 12 lines]
> Parkinsons disease is because some types of bacteria and fungus live
> better in Canada.
When I first began to take on the challenge of discovery of what causes
prion disease in the mid to late 1990s it was because I instinctively
sensed that the Prusiner Model was utterly defective and flawed. And I
started that trip of exploration of what really causes prion disease with a
great analogy. I remembered that ants are attacked by a fungus that when
they breathe the fungus it goes to the brain of the ant and causes the ant
to climb the highest branch and then dies and the fungus emits thousands of
spores to infect more ants. So if fungus find a happy medium in ant brains
then it is easy to step into an analogy that Prion disease is a fungal
caused disease in humans much like ants.
But I wish that in mid 1990s I had had a well formed Set of Ideas that
would not take hold of me until 2000s. What I mean is that around the first
few years of 2000 I began to realize that the 3 diseases of Prion,
Alzheimers and Parkinsons were family-related-diseases and that what
happens or causes one of them is pretty much close to what happens in the
other two diseases. So that if bacteria and fungus cause Parkinsons, then,
pretty much the case that bacteria and fungus have a major role in Prion
and Alzheimers. There are differences but there are more similarities
between the three.
So the mistake of Mr. Prusiner was to take the attitude that Prion is a
whole new disease, isolated and bereft of all other diseases. And that the
mechanism and cause of Prion is totally and wholly new to the world.
Sometimes science really does have something new but rarely. As good
scientists we should abide with the idea that when confronted for the first
time with what appears to be a new disease. We should not do what Mr.
Prusiner did by calling for new mechanisms. Instead we should be
**patient** and seek to categorize the new found disease into a group of
existing diseases. That is the first step and which Mr. Prusiner utterly
neglected and disregarded.
In the ANNALS OF NEUROLOGY, June 21, 2004 was reported by McNaught, Pearl,
Brownell, Olanow in an article "Systematic Exposure to Proteasome
Inhibitors Causes a Progressive Model of Parkinson's Disease"
There was no mention of the species of fungus but it said that bacteria and
fungus found in well water causes Parkinsons. The bacteria was named as
actinomycetes.
I know a fungus of YEAST produces prion proteins. So I wonder if the fungus
studied in that report is similar to the Yeast fungal species.
I know that in Alzheimers a rogue scissors cuts the protein in a bad cut
leaving a debris particle that accumulates and is the embodiment of the
disease. So, now, I wonder if there is a bacteria or fungus that mimics or
resembles this protein cutter molecule.
This is how medical science should work when a seemingly new disease is
discovered. In that we do not march off to the lab like Mr. Prusiner and
dream up unique and new mechanisms, nay, instead we place the new found
disease into a group of old known diseases that resemble each other and
then we borrow from one to the other until we systematically uncover all
the mysteries involved in that family-related-diseases.
I am anxious to know what the fungus found in well water that causes
Parkinsons and whether that fungus is related to the yeast fungus species
and whether that fungus is related to the fungus that infects the brains of
ants.
I am anxious to know whether any bacteria or fungus resembles the protein
cutter involved in Alzheimers.
P.S. One fact about all of these 3 diseases that should have alerted
smarter scientists working in this field. The contradictory fact that prion
disease is hereditary. If a disease is hereditary, then the likelihood that
a Prusiner Model is true is very low probability. Hereditary and Prusiner
Model are contradictory in relation to how the disease progresses. What is
not contradictory is if a disease is hereditary such as Prion but that
bacteria or fungus can accelerate the disease onset and progression.
Archimedes Plutonium
www.iw.net/~a_plutonium
whole entire Universe is just one big atom where dots
of the electron-dot-cloud are galaxies
Archimedes Plutonium - 04 Jan 2005 08:46 GMT
In the news today was word that stem-cells reverse the Parkinsons disease. If
true, then since Alzheimers and Prion are a family-related diseases would
indicate a better than 50% chance that stem-cells also reverse Alzheimers and
Prion victims, simply because they are so closely related.
How would embryonic stem cells reverse any one of these 3 diseases? The report
I read had no talk of a mechanism other than to say replenishment of old dead
neurons.
But perhaps a hint of how stem cells may reverse these diseases is that
perhaps the stem cells have a means of intercell communication. An
intercellular communication of protein synthesis is interrupted and making the
overall brain think it is a youthful brain. In all 3 of these diseases the
onslaught is in old age and perhaps the brain cells know it is "old age". But
when embryonic stem cells are introduced, the surrounding cells are tricked
into thinking it is a young brain and the sequencing is altered back to a
young brain. And so the alpha synuclein in Parkinsons is re-sequenced back to
a young brain sequencing.
Likewise for the APP scissors in Alzheimers that produces the rogue beta
amyloid and likewise for the rogue prion protein in CJD and other prion forms.
I do not know why stem cells reverse any one of these diseases, if it in fact
does so, or whether it is a mere amelioration of the symptoms. But if stem
cells really do reverse any one of these diseases then they probably reverse
all 3 of them and the mechanism I can imagine is perhaps related to this
trickery of intercellular communication that the brain is young again and to
alter the protein synthesis.
That is just a guess on my part.
Archimedes Plutonium
www.iw.net/~a_plutonium
whole entire Universe is just one big atom where dots
of the electron-dot-cloud are galaxies