<<snip>>
The only sign of multiple myeloma was the extremely high level of iron
<<snip>>.

Orv Hetil. 2003 Sep 14;144(37):1829-32. Related Articles, Links  

[Therapy resistant leg ulcer caused by multiple myeloma]

[Article in Hungarian]

Bago A, Schweitzer K, Kis M, Furesz J, Vajda A, Balo-Banga JM.

Magyar Honvedseg Kozponti Honvedkorhaz Borgyogyaszati Osztaly.

The authors review an elderly woman suffering from leg ulcer with bad
curability which was a consequence of a malignant haematologic disease.
Multiple relapse of this ulcer was observed and did not react to usual
conservative therapy. The only sign of multiple myeloma was the extremely high
level of iron measured in the blood serum bound to a monoclonal paraprotein.
Sternum aspiration was made and the sample showed presence of plasmoblasts
supporting diagnosis of multiple myeloma. The poor therapeutical results were
caused by hyperviscosity syndrome in consequence of the high level of the
monoclonal component in the blood serum. The ulcer was cured within eight weeks
by suppression of the monocloclonal component and thus, elimination of
hyperviscosity. This case is a special one from several points of view. Leg
ulcers not reacting to usual therapy may be caused by haematologic disease thus
the physician should consider this and extend examinations as well and
necessarily hospitalize patient. Appearance of multiple myeloma is unusual in
this case. Hystology made from the skin excised from the periphery of the wound
has not showed signs of pyoderma gangrenosum, which is known mostly being
associated with multiple myeloma.

Publication Types:
Case Reports

PMID: 14596021 [PubMed - indexed for MEDLINE]

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