High CRP Levels

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John - 30 Nov 2004 17:42 GMT

Hello all,
I understand that the normal range of C-Reactive Protein is 0-10mg/L,
and that a hsCRP test is used for evaluating CRP as a cardiac risk
factor.

Is long-term raised CRP implicated in heart disease? By that, I mean a
raised CRP above 10mg/L due to long-term inflammation from
Polymyalgia or a long-term infection.

What is considered to be a high level during infection? Is 190 high?

Thanks,
John

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listener - 30 Nov 2004 18:02 GMT

> Hello all,
> I understand that the normal range of C-Reactive Protein is 0-10mg/L,
[quoted text clipped - 9 lines]
> Thanks,
> John

My last bloodwork shows the reference interval for cardiac CRP at 0-3.00
mg/dL with a high relative risk for future cardiovascular event(s) greater
than 3.00 mg/dL.

There is an overwhelming abundance of data that statin drugs lower CRP
levels. One study (Circulation journal) showed that simvastatin lowered CRP
levels in just two weeks. Of course that has to be weighed with the risks
of taking a statin.

[Interesting note for conspiracy theorists: A lot of the CRP research is
being done at Brigham and Women?s Hospital, which owns the patents on
inflammatory markers for cardiovascular disease.]

L.

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outrider@despammed.com - 30 Nov 2004 19:44 GMT

> Hello all,
> I understand that the normal range of C-Reactive Protein is 0-10mg/L,
[quoted text clipped - 9 lines]
> Thanks,
> John

Australian Clinical Reference Range below. Are you taking prednisone
for your polymyalgia? If prednisone (or similar) reduces the
inflammation I would think your CRP would drop -- if that is the only
reason for the elevation.
http://www.hoslink.com/LabResults/refranges.htm

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