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Medical Forum / General / General / December 2004

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CRESTOR: NEW WARNINGS

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outrider - 25 Nov 2004 22:35 GMT
Health Canada reviewing safety profile of Crestor

from Health Canada, dated Nov 24

Updated safety information regarding Crestor®

OTTAWA - Health Canada wishes to advise Canadians of safety concerns
about Crestor®, a cholesterol lowering drug, when used at the highest
recommended dosage of 40 mg daily. The risk of rhabdomyolysis (muscle
breakdown) may be increased at higher doses. Health Canada recommends
that all patients taking Crestor®, or any cholesterol lowering drug,
should be using the lowest dose that will meet their treatment goal.

Health Canada is actively reviewing the safety profile associated with
rosuvastatin (Crestor®), particularly the 40 mg dose, and is in
receipt of additional safety information provided by its manufacturer,
AstraZeneca Canada Inc.

In June 2004, Health Canada posted a Public Advisory about an
association between Crestor and rhabdomyolysis, a rare but serious
muscle disorder. The same month, AstraZeneca Canada Inc. issued a Dear
Healthcare Professional Letter to advise Canadian healthcare
professionals of this information.

Rhabdomyolysis is a condition that results in muscle breakdown and the
release of muscle cell contents into the bloodstream. Symptoms of
rhabdomyolysis include muscle pain, weakness, muscle tenderness, fever,
dark urine, nausea, and vomiting. In severe cases, rhabdomyolysis can
result in kidney failure and can be life-threatening.

Since June 2004, Health Canada has received a further 6 reports of
rhabdomyolysis in patients using Crestor® which are under assessment.

All patients taking Crestor®, or any cholesterol lowering drug, are
advised to report any unexplained muscle pain, muscle weakness or
cramps, or any brown or discoloured urine, to their physician
immediately.

-30-
Steve Harris  sbharris@ROMAN9.netcom.com - 26 Nov 2004 08:05 GMT
> Health Canada reviewing safety profile of Crestor
>
[quoted text clipped - 8 lines]
> that all patients taking Crestor , or any cholesterol lowering drug,
> should be using the lowest dose that will meet their treatment goal.

COMMENT:

Katie usually felt fine, had no problems to fix,
And her grandparents all lived past ninety and six,

But they drew her blood anyway, just to see how it was,
And they looked at the lipids and started to buzz---

They'd have been fine last year, but standards had changed
And the new limits now put them quite out of range,

So the doctor said "Katie, get that LDL low;
You'll have to look at your food and say 'NO.'

So Katie tried Ornish, and then she tried Atkins
And then she did South Beach and went to Camp Fatkins

And the more foods she gave up, the more cravings she got
And her weight, though once stable, now skywardly shot.

So she ran and she ran, though a gray awful city
And her soul filled her up with the cruelest self-pity

And so desperate and anxious, but still not quite ill
She finally asked for a fix in a pill,

"Why, I have just the thing," said her doc to her then,
"It's the newest drug out, with a rocket-ship pen!"

"Oh, the pill on TV!" exclaimed Katie hard,
"With the comforting verses from Jean-Luc Picard"

"And they sound like that book with the Green Eggs and Ham
Which is what all those diets are like, where I am."

"Would you like to try it?" said the doctor, "You could..."
"Why yes," said Katie, "Why yes, yes I would."

And a door to a meadow now opened; birds sang
And the door to the ghetto went shut with a bang

And the sunshine poured out from the drugs in the bottles:
Katie's LDL dropped like a vomiting model's.

And from then on, she ate what she jolly-well pleased,
And quit running, and saved what was left of her knees.

And she happily exclaimed, going back to her life:
"I'm so glad that I'm done with cholesterol strife;

"My legs, they still ache, and I can't feel my feet,
And my urine's as pink as the time I ate beets,

"But at last, I now have my LDL LOW,
And I've finally escaped from the foul land of 'NO'.

"And I won't have to die now of heart attack brewing---
I'm SO glad that somebody knows what they're doing!"

--Steve Harris
outrider - 26 Nov 2004 17:22 GMT
Harris for Poet Laureate.

Zee
Dr. Andrew B. Chung, MD/PhD - 27 Nov 2004 21:23 GMT
> > Health Canada reviewing safety profile of Crestor
> >
[quoted text clipped - 28 lines]
> And the more foods she gave up, the more cravings she got
> And her weight, though once stable, now skywardly shot.

So instead of giving up on foods, she started to eat less
She got a little hungrier but her health did God bless

Soon her blood pressure and cholesterol had come down
On top of that, she could wear last year's gown :-)

"Katie, how did you do it?" they wanted to broach
The answer was simply the 2PD Approach !

:-)

Why do I care?

It is written in Ephesians 2:

10For we are God's workmanship, created in Christ Jesus to do good
works, which God prepared in advance for us to do.

All is a waste of time until you find the way to eternal life with the
Creator of the universe.  When you do, there is no waste of time
because there will be an infinite amount of it.  Walking about
aimlessly thinking it is *your* time, *your* money, *your* lot, *your*
labor, *your* profit, and *your* power that you are using is
tantamount to self-worship.

For Christ lights up the way through John 14:

6Jesus answered, "I am the way and the truth and the life. No one
comes to the Father except through me..."

This bring us back again to the following very simple decision tree
for the untruthful folks such as yourself, Steve, who have chosen to
walk in the "dark":

(1) Accept Christ.
Risk: Nothing.

Benefits: Salvation, purposeful life, eternal life, unimaginable
riches in God's eternal kingdom.

(2) Reject Christ.
Risk: Eternal separation from God.  Eternal torment of your soul by
satan.

Benefits: Nothing.

Again, one has to conclude that those (ie you, Carey, Bob, Zee, Frank,
Hawki, Rolando, Don et al) who would reject Christ have not thought
out their decision *logically*.

Would suggest you cast a glance at Bob Pastorio as a special example
of untruthfully eloquent self-worship (BTW, Bob remains in my prayers
out of Christian love) who is being driven to madness by my ignoring
him (http://makeashorterlink.com/?V29A236C9 and more recently
http://makeashorterlink.com/?K50B237D9).  All this power belongs to
God who has judged Bob Pastorio with His Word
(http://makeashorterlink.com/?G33F51E69). All praises to Him, Whom I
love with all my heart, soul, mind, and strength :-)

You will be in my prayers, dear Steve whom I love, in Christ's holy
name.

May you accept Christ as your personal Lord and Savior, someday, so
that you too will escape satan's rule and torment of your soul after
you die.

Please do consider the following as your logic should dictate before
it is too late:

http://makeashorterlink.com/?I22222129

(Please note that God truly made this special link describing that He
is the great "I am" and that His message is as simple as the number 2
which is a number between 1 to 9 and reminds us of His 2 commandments,
the 2 arms of the cross, the 2nd part of the Trinity, the 2 finger
sign of the Prince of Peace [who remains *V*ictorious over death and
satan], and the 2PD Approach.  Let it not ever be written that Christ
did not make His presence known here on Usenet :-)

Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
http://www.heartmdphd.com/

**
Who is the humblest person in the universe?
http://makeashorterlink.com/?L26062048

What is all this about?
http://makeashorterlink.com/?R20632B48

Is this spam?
http://makeashorterlink.com/?N69721867
beachhouse - 29 Nov 2004 17:25 GMT
"Steve Harris sbharris@ROMAN9.netcom.com" <sbharris@ix.netcom.com> wrote in
message news:79cf0a8.0411260005.66083ef6@posting.google.com...
> "Oh, the pill on TV!" exclaimed Katie hard,
> "With the comforting verses from Jean-Luc Picard"
[quoted text clipped - 4 lines]
> "Would you like to try it?" said the doctor, "You could..."
> "Why yes," said Katie, "Why yes, yes I would."

<lol>  bravo, Steve...
William_Noyes - 30 Nov 2004 05:35 GMT
> "Steve Harris sbharris@ROMAN9.netcom.com" <sbharris@ix.netcom.com> wrote in
> message news:79cf0a8.0411260005.66083ef6@posting.google.com...
> > "Oh, the pill on TV!" exclaimed Katie hard,
> > "With the comforting verses from Jean-Luc Picard"

Remember Jean-Luc Picard has a synthetic heart and Borg nanobots clearing
his arteries:-).
However, the actor who plays Picard and who intones his part on the
Crestor advert was more recently carted off to OR for emergency bypass
surgery.

> > "And they sound like that book with the Green Eggs and Ham
> > Which is what all those diets are like, where I am."
[quoted text clipped - 3 lines]
>
> <lol>  bravo, Steve...
outrider - 30 Nov 2004 10:33 GMT
Harris outdid himself. {And this was the best stanza.}
Ya know...we could start a competition here. Mock a drug ad...

Zee
Dr. Andrew B. Chung, MD/PhD - 30 Nov 2004 12:04 GMT
> > "Steve Harris sbharris@ROMAN9.netcom.com" <sbharris@ix.netcom.com> wrote
> in
[quoted text clipped - 7 lines]
> Crestor advert was more recently carted off to OR for emergency bypass
> surgery.

Patrick Stewart did receive angioplasty in August of this year so it is
likely he knows firsthand the risks of elevated serum cholesterol and
the benefits of lowering this.


Servant to the humblest person in the universe,

Andrew

--
Dr. Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
http://www.heartmdphd.com/

**
Who is the humblest person in the universe?
http://makeashorterlink.com/?L26062048

What is all this about?
http://makeashorterlink.com/?R20632B48

Is this spam?
http://makeashorterlink.com/?N69721867
outrider - 30 Nov 2004 17:45 GMT
> > > "Steve Harris sbharris@ROMAN9.netcom.com" <sbharris@ix.netcom.com> wrote
> > in
[quoted text clipped - 15 lines]
>
> Andrew

Oh? Did Picard have an elevated serum cholesterol, or was he one of the
over 50 per cent who have a heart disease with a normal serum
cholesterol level.

Zee
Hardpan - 06 Dec 2004 06:03 GMT
>> > > "Steve Harris sbharris@ROMAN9.netcom.com"
><sbharris@ix.netcom.com> wrote
[quoted text clipped - 25 lines]
>
>Zee

Thats so true!!!
John Que - 11 Dec 2004 08:46 GMT
> >> > > "Steve Harris sbharris@ROMAN9.netcom.com"
> ><sbharris@ix.netcom.com> wrote
[quoted text clipped - 27 lines]
>
> Thats so true!!!

Did his cute young thing marry him inspite of his heart condition or because
of his
heart condition;-). Maybe she'll give him the ride of his life. She may say
"Come on honey more
...More"....he pants... goes to the rest room and takes a trimix shot, now
good for
another hour ride.
Gregory Poon - 11 Dec 2004 20:09 GMT
> Did his cute young thing marry him inspite of his heart condition or because
> of his
[quoted text clipped - 3 lines]
> good for
> another hour ride.

Maybe he'll show her the "Picard manoeuvre".

> > >> > > "Steve Harris sbharris@ROMAN9.netcom.com"
> > ><sbharris@ix.netcom.com> wrote
[quoted text clipped - 27 lines]
> >
> > Thats so true!!!
michael@monheit.com - 09 Dec 2004 19:49 GMT
This is awesome.  You should publish this beyond this thread.
Michael@Monheit.com
coben - 11 Dec 2004 10:36 GMT
why not eat healthier.

this lowers cholesterol

is cheap

has no side effects

helps the body in other ways, like say, with cancer
 
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