Hi everyone- I'm working on a technical article that shows how to
encode scientific information into a computer database (to be specific,
using description logics)

In order to illustrate this, I want to take an important historical
medical paper as an example and show how it can be encoded. To my
surprise, I was not able to find any information online on what the
"most important" medical articles are and I am unable to find a good
"famous paper" to use.

Some famous "medical related" articles I can think of is the Crick &
Watson DNA paper or the Nature "Dolly the Sheep" paper, but neither of
these are really very "medical" and are more biochemistry in subject
matter.

Other possibilities would include a paper on the Framingham Study or
maybe the HIV->AIDS discovery, but neither of these discoveries have a
single, authorative publication that defines them.

Does anybody have a good recommendation for a paper I could use?
Thanks!

-----
Conrad Barski, M.D.