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Medical Forum / General / General / September 2004How to treat Sever Aplastic Anemia
My patient had pancytopenia despite our platelet transfusion his platelet still around 7K We are afraid of spontaneously bleeding please tell me how to treat this patient Thanks Kuo >My patient had pancytopenia >despite our platelet transfusion >his platelet still around 7K >We are afraid of spontaneously bleeding >please tell me how to treat this patient >Thanks If the patient has antibodies that are destroying donor platelets, you could try a continuous a platelet drip (one unit over 4 hours, that is, 6 units per 24 hours), or try to obtain HLA-matched platelets. PF > My patient had pancytopenia > despite our platelet transfusion [quoted text clipped - 4 lines] > > Kuo Are you sure the patient has aplastic anemia? Has he had prior platelet transfusions? It would be surprising not to get a bump in the platelet count with a first platelet transfusion in someone with aplastic anemia. After the patient has had multiple transfusions, though, he can develop antibodies and may not respond well to platelet transfusions. -- David Rind drind@caregroup.harvard.edu |
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