If you want detailed information about medical information, go to PUBMED and
look at the abstracts of most all published medical articles in the last 3 or
4 decades: http://www.ncbi.nlm.nih.gov/PubMed/
While there's not a lot of information about Acetylcholine and neurontin,
here's one interesting lab study:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1
1578817&dopt=Abstract
From that, it appears that neurontin may cause a centrally acting stimulation
of acetylcholine receptors, since a drug like atropine, that blocks the
receptors, were able to prevent the memory improving actions of neurontin.
So neurontin would be a good thing.
There is some belief that neurontin can help with muscle problems like yours,
but there haven't been a lot of actual studies. One of the main problems with
neurontin is that it has to be taken frequently enough to keep serum levels
elevated. It's definitely worth a try if nothing else has worked, since it's
actions are very different than most other drugs.
There's a NEURONTIN-L mailing list that you could sign on to, if you want more
information. That list is mainly for people taking neurontin for pain, but
there probably is someone there who could tell you more about any effects
neurontin has for spasms.
In a previous article, "Robert11" <rgsxrose@comcast.net> wrote:
->Hello:
->
->Have a strong facial muscle contraction problem caused by trauma which is
->presently
->being treated with Botox. This has been only partially successful.
->
->It has been suggested that I try Neurontin, but have several concerns and
->questions regarding its usage. If anyone can answer all (or any) of the
->following,
->would be most appreciative.
->
->a. Has Neurontin been successful in decreasing muscle contractions
->caused by facial trauma ?
->
->b. Does Neurontin decrease the transmission of the neurotransmitter
->Acetylcholine, and therefore decrease muscle contractions ?
->
->c. Does this happen to all nerves throughout the body (e.g., is it global
->in its effect),
->or is it selective ? How does it discriminate ?
->
->d. Does it also decrease the transmission of the other neurotransmitters
->throughout
->the body ?
->
->e. Acetylcholine (in the drug Aricept) is taken to prevent dementia and
->Alzheimer's.
->Does decreasing the amount of this chemical in the brain increase the
->chances
->of bringing on these conditions ?
->
->f. Can the decrease of the other neurotransmitters bring on other
->conditions ?
->
->Much thanks; appreciate any help very much.
->
->B.
-