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Medical Forum / General / General / January 2004Cinnamon / insulin action / glucose intolerance
J Agric Food Chem. 2004 Jan 14;52(1):65-70. Links Isolation and Characterization of Polyphenol Type-A Polymers from Cinnamon with Insulin-like Biological Activity. Anderson RA, Broadhurst CL, Polansky MM, Schmidt WF, Khan A, Flanagan VP, Schoene NW, Graves DJ. Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research Center, USDA, ARS, Bldg 307C, Rm 223, Beltsville, Maryland 20705-2350, Nuclear Magnetic Resonance Laboratory, ARS, USDA, Beltsville, Maryland 20705-2350, Food Composition Laboratory, Beltsville Human Nutrition Research Center, USDA, ARS, Beltsville, Maryland 20705-2350, and Department of Molecular Cellular and Developmental Biology, University of California, Santa Barbara, California 93106-9610. The causes and control of type 2 diabetes mellitus are not clear, but there is strong evidence that dietary factors are involved in its regulation and prevention. We have shown that extracts from cinnamon enhance the activity of insulin. The objective of this study was to isolate and characterize insulin-enhancing complexes from cinnamon that may be involved in the alleviation or possible prevention and control of glucose intolerance and diabetes. Water-soluble polyphenol polymers from cinnamon that increase insulin-dependent in vitro glucose metabolism roughly 20-fold and display antioxidant activity were isolated and characterized by nuclear magnetic resonance and mass spectroscopy. The polymers were composed of monomeric units with a molecular mass of 288. Two trimers with a molecular mass of 864 and a tetramer with a mass of 1152 were isolated. Their protonated molecular masses indicated that they are A type doubly linked procyanidin oligomers of the catechins and/or epicatechins. These polyphenolic polymers found in cinnamon may function as antioxidants, potentiate insulin action, and may be beneficial in the control of glucose intolerance and diabetes. PMID: 14709014 [PubMed - as supplied by publisher] -------------------------------------------------------------------------- ------ Who loves ya. Tom  SignatureJesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking Comment: The anthocyanidins are the colors in red and blue fruit like blueberries and cranberries. And there's already a limited amount of evidence that these things influence glucose tolerance positively. For example see the following study where insulin levels in type II diabetics were basically halved by cranberry extract. http://www.findarticles.com/cf_dls/m0CUH/9_26/107928450/p1/article.jhtml I'm told that OceanSpray already maintains a small unit which supplies sugar-free cranberry juice (yow-- sour!) to a small but fanatical market of diabetics, who presumably pucker up but drink it and swear by it. The cinnamon results below are all along this line. But if I had diabetes I'd be wolfing cranberry extract. SBH > J Agric Food Chem. 2004 Jan 14;52(1):65-70. Links > [quoted text clipped - 39 lines] > Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore > DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking seven identical posts spam shilling reported On 10 Jan 2004 14:33:01 -0800, sbharris@ix.netcom.com (Steve Harris sbharris@ROMAN9.netcom.com) wrote: >Comment: > [quoted text clipped - 60 lines] >> Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore >> DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking >Subject: Re: Cinnamon / insulin action / glucose intolerance >From: Mack asdnospam@example.com >Date: 1/13/2004 4:57 AM Mountain Standard Time >Message-id: <nbf5005eq6k054llkr2viuam2s46mjdhth@4ax.com> > >seven identical posts spam shilling reported Step up .. you little piece of crap .. You KNOW there is no shilling .. and you STILL .. report .. eh .. That is because you are a pussy .. I've always figured that .. And as always .. You do not fail to confirm .. P .. u .. s .. s .. s .. s .. s .. yyyyyyy Who loves ya. Tom SignatureJesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking > Comment: > [quoted text clipped - 3 lines] > example see the following study where insulin levels in type II > diabetics were basically halved by cranberry extract. This would appear to be an alternative to Glucophage (at least for non-diabetics looking to reduce insulin levels for health reasons). A few months or so ago the Life Extension Foundation published studies showing that Glucophage (Metformin) mimiced the effects of calory restriction. Glucophage is an insulin sensitizer. It looks like Cranberry extract does the same thing. -Bruce Comment: Anthocyanidins are the colors in ripe berries like blueberries and cranberries. It's already known that they positively influence glucose tolerance: for example see http://www.findarticles.com/cf_dls/m0CUH/9_26/107928450/p1/article.jhtml Where insulin levels were halved (p < 0.05) by cranberry extract, as compared with placebo. I'm told that OceanSpray maintains a small output of (yow-- sour!) sugar-free cranberry juice output for a small group of puckered up diabetics who drink it and swear by it. The cinnamon results are all along this line, but if I had diabetes I'd be eating cranberry extract instead. SBH > J Agric Food Chem. 2004 Jan 14;52(1):65-70. Links > [quoted text clipped - 30 lines] > > PMID: 14709014 [PubMed - as supplied by publisher] Comment: Anthocyanidins are the colors in ripe berries like blueberries and cranberries. It's already known that they positively influence glucose tolerance: for example see http://www.findarticles.com/cf_dls/m0CUH/9_26/107928450/p1/article.jhtml Where insulin levels were halved by cranberry extract. I'm told that OceanSpray maintains a small output of (yow-- sour!) sugar free cranberry juice output for a small group of puckered up diabetics who drink it and swear by it. The cinnamon results are all along this line, but if I had diabetes I'd be eating cranberry extract instead. SBH > J Agric Food Chem. 2004 Jan 14;52(1):65-70. Links > [quoted text clipped - 74 lines] > Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore > DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking Comment: Anthocyanidins are the colors in ripe berries like blueberries and cranberries. It's already known that they positively influence glucose tolerance: for example see http://www.findarticles.com/cf_dls/m0CUH/9_26/107928450/p1/article.jhtml Where insulin levels were halved by cranberry extract. I'm told that OceanSpray maintains a small output of (yow-- sour!) sugar free cranberry juice output for a small group of puckered up diabetics who drink it and swear by it. The cinnamon results are all along this line, but if I had diabetes I'd be eating cranberry extract instead. SBH > J Agric Food Chem. 2004 Jan 14;52(1):65-70. Links > [quoted text clipped - 74 lines] > Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore > DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking Comment: Anthocyanidins are the colors in ripe berries like blueberries and cranberries. It's already known that they positively influence glucose tolerance: for example see http://www.findarticles.com/cf_dls/m0CUH/9_26/107928450/p1/article.jhtml Where insulin levels were halved by cranberry extract. I'm told that OceanSpray maintains a small output of (yow-- sour!) sugar free cranberry juice output for a small group of puckered up diabetics who drink it and swear by it. The cinnamon results are all along this line, but if I had diabetes I'd be eating cranberry extract instead. SBH > J Agric Food Chem. 2004 Jan 14;52(1):65-70. Links > [quoted text clipped - 74 lines] > Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore > DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking Comment: Anthocyanidins are the colors in ripe berries like blueberries and cranberries. It's already known that they positively influence glucose tolerance: for example see http://www.findarticles.com/cf_dls/m0CUH/9_26/107928450/p1/article.jhtml Where insulin levels were halved by cranberry extract. I'm told that OceanSpray maintains a small output of (yow-- sour!) sugar free cranberry juice output for a small group of puckered up diabetics who drink it and swear by it. The cinnamon results are all along this line, but if I had diabetes I'd be eating cranberry extract instead. SBH > J Agric Food Chem. 2004 Jan 14;52(1):65-70. Links > [quoted text clipped - 74 lines] > Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore > DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking Steve Harris sbharris@ROMAN9.netcom.com wrote: > The cinnamon results are all along this line, but if I had diabetes > I'd be eating cranberry extract instead. I heard you the first time. :-) Better clean your 'send' button. > Steve Harris sbharris@ROMAN9.netcom.com wrote: > > The cinnamon results are all along this line, but if I had diabetes > > I'd be eating cranberry extract instead. > > I heard you the first time. :-) Better clean your 'send' button. Appologies. The fault is with GoogleGroups, which I'm using for my Usenet access. This time they kept giving me a "timed out cannot find page" message, when the message had actually been sent. So I kept trying until I finally got a "posted" confirmation. But the service, as it turns out, had actually been posting every copy, and without emailing me one, either. Because Google has a 3-9 hour delay on seeing what you've posted, it's not obvious when you've done a duplicate post. I'd erase the extras, but google doesn't give you that option, either. You get what you pay for. SBH Comment: Anthocyanidins are the colors in ripe berries like blueberries and cranberries. It's already known that they positively influence glucose tolerance: for example see http://www.findarticles.com/cf_dls/m0CUH/9_26/107928450/p1/article.jhtml Where insulin levels were halved by cranberry extract. I'm told that OceanSpray maintains a small output of (yow-- sour!) sugar free cranberry juice output for a small group of puckered up diabetics who drink it and swear by it. The cinnamon results are all along this line, but if I had diabetes I'd be eating cranberry extract instead. SBH > J Agric Food Chem. 2004 Jan 14;52(1):65-70. Links > [quoted text clipped - 30 lines] > > PMID: 14709014 [PubMed - as supplied by publisher] |
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