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Medical Forum / General / General / February 2009

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Question about endoscopy with Botox

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Jane - 19 Feb 2009 01:06 GMT
I was wondering if anyone has had this procedure.

My husband has been having a lot of trouble swallowing.  Half the time
he end up throwing up because the food or liquid gets stuck in his
throat.  An endoscopy showed that the valve that connects the
esophagus to the stomach does not open.  The are going to inject Botox
into the valve to relax it.

I was wondering how long after the procedure the valve would open?
I've left messages for the doctor but haven't heard back yet.  I do
understand that it's quite successful, although it is only temporary.

My husband has cancer.  He has lost an enormous amount of weight.
Partly from the cancer of course, but not being able to eat normal
food hasn't helped at all.  Even water can be a problem.
H McCollister - 20 Feb 2009 16:20 GMT
In article
<05ac95cb-04c5-4713-85c7-35173be02420@f3g2000yqf.googlegroups.com>,

> I was wondering if anyone has had this procedure.
>
[quoted text clipped - 11 lines]
> Partly from the cancer of course, but not being able to eat normal
> food hasn't helped at all.  Even water can be a problem.

I presume that your husband has been diagnosed with achalasia?

What kind of cancer does your husband have? What were the results of his
manometry testing? What did his barium swallow show?

Injecting the lower esophageal sphincter with botox is a bad idea in an
otherwise healthy patient. It is temporary, will have to be repeated
every 2-3 months, and can make the operation that will ultimately be
required increasingly difficult with each injection. That operation
(Heller esophagomyotomy) is done laparoscopically and typically is an
overnight stay in the hospital.

OTOH, in a patient that is terminal and only has a year or less to live,
botox could be reasonable palliation.

HMc
J - 21 Feb 2009 10:13 GMT
> In article
> <05ac95cb-04c5-4713-85c7-35173be02420@f3g2000yqf.googlegroups.com>,
[quoted text clipped - 31 lines]
>
> HMc

Thank you, Howard.
He has lung cancer (type unknown), spread to the liver and the bones.
He's 78 and has had ""very mild" congestive heart failure.
Protein in the urine  The reading was 465.  After 3 months on Diovan (which
also makes him tired) the
protein level was almost normal at 34.   His potassium was also a little
high.  It is also at normal levels now that I've cut down on many high
potassium foods.
There is some fluid around the lung area.
he takes Coumadin for chronic atrial fibrillation (afib for more than 40
years)
Very short of breath - plans to remove fluid from around the lungs.
Tough situation, poor prognosis, I would think..
I think she will be asking the oncologist Tuesday about getting help from
hospice.

J - supplying additional information in case she has other questions
H McCollister - 21 Feb 2009 16:10 GMT
> Thank you, Howard.
> He has lung cancer (type unknown), spread to the liver and the bones.
[quoted text clipped - 13 lines]
>
> J - supplying additional information in case she has other questions

Tough situation indeed, and with this additional information, it's clear
that operative intervention (Heller esophagomyotomy) is not a good
choice for this patient.

Botox injection of the LES could be a good palliative solution to
improve swallowing and improve quality of life in this case, but only if
the difficulty swallowing is related to excessive intrinsic LES
pressure, and not external compression of the distal esophagus by tumor.
A barium swallow alone may not be sufficient to make that distinction.

HMc
 
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