Home | Contact Us | FAQ | Search & Site Map | Link to Us
Sign In | Join | Other 45 Sites in Network
Home
Discussion Groups
General
GeneralCardiologyVisionDentistryPharmacyLaboratoryNutritionAlternative
Diseases and Disorders
AIDSAlzheimer'sArthritisAsthmaCancerBreast CancerDiabetesEpilepsyGlaucomaHepatitisHerpesLupusProstate BPHProstate CancerProstatitisSinusitisTinnitus

Medical Forum / General / General / July 2008

Tip: Looking for answers? Try searching our database.

What caused my heart attack?

Thread view: 
Enable EMail Alerts  Start New Thread
Thread rating: 
kawangku - 19 Jul 2008 05:31 GMT
I'm a healthy, active, 75 years old man with NO diabetes and
cardiovascular problem and NO any other medical history.

After an uneventful leg operation, my leg wound is managed by VAC
therapy system, recuperating in the isolated ward and recovering very
well.

On the fourth day evening after the operation, I found I was in the
ICU and told I had a silent hearth attacked. Before the attacked, I
was very pale, have rapid pulses, low BP, breathlessness,
semiconcious, and was given IV NaCl.

Biochemistry done during the heart attack showed these abnormal
parameters:
Hb=4.2, heamatocrit=14.8, AST=1221, ALT= 631, LDH= 58, CK=1370,
CKMB=101, troponin= 11.75

I survive with: initially, complete renal failure (no urine),
pulmonary edema, pleural effusion. Thank god, all returned to normal
after 3 weeks. However, echocardiography revealed my left heart
chambers dilated, mild aortic & mitral valves regurgitation, regional
wall motion abnormalities and left ventricular systolic dysfunction.
I’m on beta blocker tablets which doc says is good for my heart and I
currently feel ok except talking softly, slight breathless on
exertion.

Can expert enlighten me:

What have caused my heart attack?

What is the most appropriate treatment for my heart condition?

Will my heart function recover to normal?

Thanks in advance

Cheng
ironjustice@aol.com - 19 Jul 2008 17:04 GMT
On Jul 18, 9:31 pm, kawangku <burongor...@yahoo.com.sg> wrote:CK=1370
<<

Hemolysis ..

Why .. ?

Could be a .. few .. reasons.

Vol. 33, No. 3, 1993

Original Paper

Clinical Spectrum of McArdle Disease: Three Cases with Unusual
Expression
L. Chiadò-Piat, T. Mongini, C. Doriguzzi, M. Maniscalco, L. Palmucci

Paolo Peirolo Center for Neuromuscular Diseases, 2nd Division of
Neurology, University of Turin, Italy

Address of Corresponding Author

Eur Neurol 1993;33:208-211 (DOI: 10.1159/000116938)

 Abstract

Three cases of myophosphorylase deficiency with unusual clinical
expression are presented.
The 1 st had clinical characteristics suggesting a mild congenital
myopathy, and the patient never experienced cramps or myalgias.
The 2nd had a slowly progressive myopathy without cramps or
myoglobinuria which was detected by chance.
The 3rd presented with myoglobinuria and acute renal failure,
unrelated to a triggering effort, and with permanent weakness and
wasting.
In all cases, muscle biopsy demonstrated a vacuolar myopathy with free
glycogen increase and absence of myophosphorylase activity, confirmed
by biochemical assays.
The cases confirm the wide clinical spectrum of McArdle disease.

Copyright © 1993 S. Karger AG, Basel

--------------------------------------------------------------------------------

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh

Man Is A Herbivore!
http://tinyurl.com/4rq595

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

> I'm a healthy, active, 75 years old man with NO diabetes and
> cardiovascular problem and NO any other medical history.
[quoted text clipped - 33 lines]
>
> Cheng
ironjustice@aol.com - 19 Jul 2008 17:10 GMT
On Jul 19, 9:04 am, "ironjust...@aol.com" <ironjust...@aol.com> wrote:
On Jul 18, 9:31 pm, kawangku <burongor...@yahoo.com.sg> wrote:CK=1370
Hemolysis ..<<

The effect of hemolysis on creatine kinase determination.
Arch Pathol Lab Med. 1989 Feb;113(2):184-5.Links
Comment in:
Arch Pathol Lab Med. 1992 Jan;116(1):7-8.
Greenson JK, Farber SJ, Dubin SB.
Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical
Center, Los Angeles, CA 90048.

Hemolysis can cause falsely elevated creatine kinase (CK) values when
spectrophotometric methods of measurement are used.
This apparent increase in CK is due to the red blood cell enzyme
adenylate kinase. In an attempt to reduce this interference, most
commercial CK kits employ adenosine monophosphate and/or diadenosine
pentaphosphate as adenylate kinase inhibitors.
To determine whether hemolyzed specimens should be accepted for
testing, we measured the CK values of 26 serum samples, each with six
different concentrations of added hemolysate.
The results showed that hemolysis had an additive effect on CK, with
an average increase in CK of approximately 10 U/L for every 1 g/L of
hemoglobin.
In most settings, this increase is not clinically significant. In the
case of massive hemolysis, the hemoglobin concentration of the serum
can be measured to correct the apparent CK value.
The exclusion of hemolyzed specimens is unnecessary.

PMID: 2916906 [PubMed - indexed for MEDLINE]

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh

Man Is A Herbivore!
http://tinyurl.com/4rq595

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

> Why .. ?
>
[quoted text clipped - 83 lines]
>
> - Show quoted text -
Kawang - 20 Jul 2008 08:43 GMT
On Jul 20, 12:10 am, "ironjust...@aol.com" <ironjust...@aol.com>
wrote:
> On Jul 19, 9:04 am, "ironjust...@aol.com" <ironjust...@aol.com> wrote:
> On Jul 18, 9:31 pm, kawangku <burongor...@yahoo.com.sg> wrote:CK=1370
[quoted text clipped - 125 lines]
>
> - Show quoted text -

--------------------------------------------------------------------------------------------------------------------------

Obviously I had  AMI as from the cardial markers & ECG findings which
I found from some of the hospital data.
Other than old age and being a male, I have no other risk factors for
the AMI ( as I mentioned from start ).

My successful operated (for necrotizing faciitis) leg wound was
managed by VAC (Vacuum Assisted Closure) therapy system which
constantly draining fluid and blood from the dressing which MOST
LIKELY the after-care medical staffs neglected the replenishment of
fluid and plasma. Just before the heart attack, I was very pale, rapid
pulses, low BP, breathlessness, semiconcious, and Heamatocrit=14.8,
Hb=4.2 are the solid evidences of Hypovolemia. Fortunately, at the
very last minute, a senior medical noticed my signs and symptoms of
heart attack and instantly ordered the juniors rushed me to ICU.

Therefore, my AMI and renal failure were not due to VAT, coronary
plaque and/or occlusion, but hypovolemia and hypoxia, which I hope
there are constructive opinions from Internet community. Sadly, I see
people talking from God and Hunger to sarcasm.  CHENG.
ironjustice@aol.com - 20 Jul 2008 12:59 GMT
On Jul 20, 12:43 am, Kawang <alanperw...@gmail.com> wrote:Sadly, I see
people talking from God and Hunger to sarcasm.  CHENG <<

Don't believe it is hemolysis .. ?

Fine ..

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh

Man Is A Herbivore!
http://tinyurl.com/4rq595

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
 
Sign In
Join
My Latest Posts
My Monitored Threads
My Blog
My Photo Gallery
My Profile
My Homepage

Start New Thread
Enable EMail Alerts
Rate this Thread



©2008 Advenet LLC   Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.