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Medical Forum / General / General / January 2008

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Kocking out two genes will extend human lifespan to 800 years

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habshi - 24 Jan 2008 23:38 GMT
    There was a guy called Methesulah whose genes were knocked by
the big bully up there. Where will find the energy and space to put
humans if nobody dies

excerpt independent.co.uk
    Valter Longo is one of the small but influential group of
specialists in this area who believes that an 800-year life isn't just
possible, it is inevitable. It was his work at the University of
Southern California that led to the creation of a strain of yeast
fungus that can live for 10 weeks or more, instead of dying at its
usual maximum age of just one week.

By deleting two genes within the yeast's genome and putting it on a
calorie-restricted diet, Longo was able to extend tenfold the lifespan
of the same common yeast cells used by bakers and brewers. The study
is published later this week in the journal Public Library of Science
Genetics.

There is, of course, a huge difference between yeast cells and people,
but that hasn't stopped Longo and his colleagues suggesting that the
work is directly relevant to human ageing and longevity. "We're
setting the foundation for reprogramming healthy life. If we can find
out how the longevity mechanism works, it can be applied to every cell
in every living organism," Longo says.
Frank Arthur - 24 Jan 2008 23:52 GMT
By the time I get to be about 200 or so I fear my sex drive might not
be as strong as it is now.
The though to a 500 or 600 year old "chick" might just turn me off!

> There was a guy called Methesulah whose genes were knocked by
> the big bully up there. Where will find the energy and space to put
[quoted text clipped - 26 lines]
> cell
> in every living organism," Longo says.

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