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Medical Forum / General / General / November 2007

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#101 NOVA spoke of human 23 chromosomes whereas apes have 24; new textbook: Stonethrowing Theory, the Central theory of Anthropology

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a_plutonium - 14 Nov 2007 21:07 GMT
TextBook:  "STONETHROWING THEORY, THE CENTRAL THEORY OF

ANTHROPOLOGY", Archimedes Plutonium

Internet book published 2002-2007 (amassed in

March 2007 in sci.anthropology.paleo, sci.med,

sci.physics)

This is now November of 2007 and after writing alot of these science
books I learned to number
them in order to keep track and to add a last chapter that allows me
to comment on recent
news flash updates.

So I wrote the above book back in March or amassed  all of my previous
posts in March to
form a textbook and last night watching Nova about Darwin and
Intelligent Design court case
in Dover Pennsylvania, they touched on something important to
Stonethrowing theory.

They said in that program that the apes of chimps, orangs and gorillas
all have 24 chromosomes
while humanity has 23. So they further go on to explain that one of
the human chromosomes
fused with another where the telomeres of one chromosome fused with
the telomeres of another
chromosome and where this fused chromosome has double the number of
centromeres.

They said it was the Human Chromosome #2 that was the fused one.

So, that immediately set my mind to wondering whether Human Chromosome
#2 is the chromosome
where much or most of the genetics of bone and muscle structure are
formed. Is it chromosome
#2 wherein lies the ability to throw overarm for humans and not for
apes? Is it Chromosome
#2 wherein lies the tremendous changes of the fingers hands arms and
backbone and rotator cuff
and elbow all to perfect Throwing?

Indeed, I must make a search to see if Chromosome #2 is where most of
the physiology of bone
and muscle structure of humans is played out.

Archimedes Plutonium
www.iw.net/~a_plutonium
whole entire Universe is just one big atom
where dots of the electron-dot-cloud are galaxies
Yousuf Khan - 23 Nov 2007 10:13 GMT
> They said in that program that the apes of chimps, orangs and gorillas
> all have 24 chromosomes
[quoted text clipped - 20 lines]
> the physiology of bone
> and muscle structure of humans is played out.

Why can't Chromosome #2 simply be the chromosome where all of the human
brain development came out of?

    Yousuf Khan
a_plutonium - 23 Nov 2007 19:59 GMT
Someone wrote:

> Why can't Chromosome #2 simply be the chromosome where all of the human
> brain development came out of?

I was not claiming that #2 chromosome is the site of where the
genetics of humanity came
into being and diverged from ape ancestors. I was saying that it is
highly likely and that it is
worthy of research to see if this chromosome bears the divergence of
humanity from ape
ancestors.

According to Stonethrowing Theory, the difference between humanity and
all other primates is
our proclivity to throw rocks and stones which catapulted our
evolution and causing us to have
bipedalism and an ever bigger brain to think out the trajectory and
consequences of throwing
rocks and stones as well as benefiting the thrower with more mates and
offspring. So if we
differ from the apes in that we have a fused chromosome as #2 and that
we differ from apes in
that we are the Throwing Ape, then logic would say that it is highly
likely that our Throwing Genetics
lies on this #2 chromosome.

So I am not saying definitely 100 percent that throwing genetics is on
#2 chromosome but saying
that it is very much likely to be the case. That the bone morphology
and the muscle genetics
that made the human anatomy into a Stonethrower is likely to have
connections to chromosome
#2.

So I was asking for a diving into research of chromosome #2 as to
whether the genetics of
bones and muscles is on chromosome #2. Whether Opposable thumb is on
#2 and whether
Rotator Cuff is on #2 and whether the apes knuckle walking is on their
so called #2.

I am saying that the major difference between humanity and the rest of
the primates is a spat
of evolution wherein we became Stonethrowers and the genetics should
bear that out.

Archimedes Plutonium
www.iw.net/~a_plutonium
whole entire Universe is just one big atom
where dots of the electron-dot-cloud are galaxies
Marc Verhaegen - 24 Nov 2007 17:23 GMT
Op 23-11-2007 20:59, in artikel
e43ae082-09ab-47f5-ab9e-2eb1ab1151b3@d61g2000hsa.googlegroups.com,
a_plutonium <a_plutonium@hotmail.com> schreef:

> According to Stonethrowing Theory, the difference between humanity and
> all other primates is
> our proclivity to throw rocks and stones which catapulted our
> evolution and causing us to have
> bipedalism and an ever bigger brain

Constructing Central Theories about the Uniqueness of Humanity is ok, but
1) throwing,
2) bipedality &
3) big brains
have nothing to do with each other:

1)
Frans de Waal, evol-psych 22.9.01: Now, please, don't believe everything you
hear about apes not throwing. Darwin was talking about monkeys, and
Goodall's chimps may not have had much practice.  In all research facilities
with chimpanzees it is known how well apes throw. This is why projectiles
are kept away from them, and why they mostly work with feces. They are
deadly accurate, they swing around from the back of their cage and
invariably "nail" the one new face in the crowd with deadly accuracy. Ask
any worker in such a facility: it's not rare, and no illusion!      Out in
the open, their skills are even more striking. I used to photograph the
Arnhem chimpanzees from across the moat, where they were at about 10 m from
me. I had to be extremely careful because young males tended to throw
extremely well. They would see my eye go behind the camera, and all of a
sudden it turned out they had a stone with them which they'd throw at me.
Males more than females, mostly overhand. (Another tidbit in the debate
whether they know if our eyes are for seeing or not …).   Then there was the
mother who came to the reception with her crying son. She complained that
our chimps threw stones. After questioning and an account by a bystander it
turned out that the boy had thrown first, and that the same stone had come
back to him. The estimated distance of this case was 25 m.          In
short, the idea that apes can't throw is bogus. It has been around for a
long time, but should be tested with apes who have had target practice. I
invite all man-the-thrower advocates for a visit - at least if they don't
mind some smelly stuff coming their way!
http://www.uncoveror.com/baboons.htm  Curious Child Causes Baboon Fracas - A
3d-grader on a school-outing to the San Jose Zoo caused an ugly scene. His
older brother told him not to throw rocks at the red-a.s baboons : when they
throw them back, they don't miss. He wanted to see if it was true. George
Simms picked up a rock , threw it at the biggest baboon he could see. It
whizzed past Bobo, dominant♂ in the Hamadryas , landed just behind him. Bobo
noticed who had thrown the rock, flew into a rage, picked it up, threw it
back, hitting little George squarely in the forehead, knocking him out cold.
The Baboon then proceeded to screech loudly, jumping up+down, showing his
teeth.   A little girl, Susan Parker, yelled "You bad monkey!" , threw the
rock a 3d time. This time it fell just short of an infant baboon. The entire
troop became agitated , started to fling rocks, dirt clods, mud & their
feces at the children, their teacher& all other Hs within sight, never once
missing a target.   As children began to drop like flies, adults began to
panic, some Pt in the display behind them thought flinging things looked
like fun, so they joined in, completely surrounding the bewildered zoo
patrons.  By the time the apes had nothing more to fling, 9 children & 3
adults lay unconscious, many others were crying & moaning in pain, bleeding
& holding on to wounds. Those only needing first aid were treated at the
zoo, the rest were rushed to nearby hospitals. The young boy who started it
all remains hospitalized in serious condition.  As little George Simms & all
his classmates learned the hard way, it is not just a myth or an old wives
tale. Don't throw rocks at the red-a.s baboons. When they throw them back,
they don't miss!"

2)
probably predates the human/gibbon split c.18 Ma or so, and mid-Miocene
fossils (Morotopithecus) had lumbar vertebrae with transverse processes on
the vertebral arch, which suggests they had an upright posture:
A.Filler 2007 "The upright ape" & recent papers.

3)
Brains larger than in apes & apiths appear AFAWK only in Pleistocene.
a_plutonium - 24 Nov 2007 19:48 GMT
Moments like this I wish I was an expert in protein function

--- quoting from http://ghr.nlm.nih.gov/chromosome=2/show/Genes
   * ABCA12: ATP-binding cassette, sub-family A (ABC1), member 12
   * ACVR1: activin A receptor, type I
   * AGXT: alanine-glyoxylate aminotransferase
   * ALMS1: Alstrom syndrome 1
   * ALS2: amyotrophic lateral sclerosis 2 (juvenile)
   * APOB: apolipoprotein B (including Ag(x) antigen)
   * ATG16L1: ATG16 autophagy related 16-like 1 (S. cerevisiae)
   * BARD1: BRCA1 associated RING domain 1
   * BMPR2: bone morphogenetic protein receptor, type II (serine/
threonine kinase)
   * CNGA3: cyclic nucleotide gated channel alpha 3
   * COL3A1: collagen, type III, alpha 1 (Ehlers-Danlos syndrome type
IV, autosomal dominant)
   * COL4A3: collagen, type IV, alpha 3 (Goodpasture antigen)
   * COL4A4: collagen, type IV, alpha 4
   * COL5A2: collagen, type V, alpha 2
   * CPS1: carbamoyl-phosphate synthetase 1, mitochondrial
   * CYP1B1: cytochrome P450, family 1, subfamily B, polypeptide 1
   * D2HGDH: D-2-hydroxyglutarate dehydrogenase
   * DCTN1: dynactin 1 (p150, glued homolog, Drosophila)
   * DFNB59: deafness, autosomal recessive 59
   * EDAR: ectodysplasin A receptor
   * EIF2B4: eukaryotic translation initiation factor 2B, subunit 4
delta, 67kDa
   * HADHA: hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme
A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha
subunit
   * HADHB: hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme
A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta
subunit
   * MSH2: mutS homolog 2, colon cancer, nonpolyposis type 1 (E.
coli)
   * MSH6: mutS homolog 6 (E. coli)
   * NR4A2: nuclear receptor subfamily 4, group A, member 2
   * OTOF: otoferlin
   * PAX3: paired box 3
   * PAX8: paired box 8
   * SLC3A1: solute carrier family 3 (cystine, dibasic and neutral
amino acid transporters, activator of cystine, dibasic and neutral
amino acid transport), member 1
   * SLC40A1: solute carrier family 40 (iron-regulated transporter),
member 1
   * TPO: thyroid peroxidase

--- end quoting from http://ghr.nlm.nih.gov/chromosome=2/show/Genes

The theme of the textbook Stonethrowing theory is that Throwing
behaviour delivered a new
species out of the ape species some 10 million years ago all due to
one new behaviour--
throwing. Where this new behaviour garnered more food, more mates and
which accelerated
the change in anatomy of these Throwing creatures to become a human
anatomy. What
makes us different from apes was a Throwing ape some 10 million years
ago. And that history
should be traceable in the genetics where the opposable thumb and
rotator cuff and the
non-knuckle-walking and the hands and fingers and the bipedalism also
came about due to the
pressure of throwing better demands bipedalism.

So one behaviour --- Throwing --- caused the existence of humanity
from apes.

And the genetics should bear it out.

I am told that Human Chromosome #2 is the second largest human
chromosome so it has
alot of genes. And from the above it appears that this chromosome has
BMPR2: bone morphogenetic protein receptor, type II (serine/threonine
kinase)

Now do the apes of chimpanzees or orangutans or gorilla or bonobo have
BMPR2?

So that if we make a gene by gene correlation where apes have a gene
but humans do not
or where humans have a muscle bone anatomy gene and apes do not. Well,
we can get to
the very heart and foundation of the science of Anthropology and
before the end of this century
that anthropology as a science should be a nearly completed science
where the only future
questions are just details.

Archimedes Plutonium
www.iw.net/~a_plutonium
whole entire Universe is just one big atom
where dots of the electron-dot-cloud are galaxies
a_plutonium - 25 Nov 2007 06:21 GMT
> Moments like this I wish I was an expert in protein function
>
[quoted text clipped - 84 lines]
> where the only future
> questions are just details.

The title says most of it. And this textbook has really come a very
long way ever since
I watched a TV program showing Pickford and Senut in Africa finding
Orrorin and then
the program talking about bipedalism and its Savannah theory. And
which the Pickford
groove in the femur was the telltale signature of bipedalism.

So in all these many years I have been looking for the unique
signature for Throwing, such
as Rotator Cuff or finger bones. When all along, if I had been smarter
I should have said,
look at the genetics and there probably exists a unique body chemical
that is unique to
the human capacity to throw overarm and with such speed and accuracy.

So I would concentrate the research for a chemical protein or hormone
by the genetics
and especially Chromosome #2.

Archimedes Plutonium
www.iw.net/~a_plutonium
whole entire Universe is just one big atom
where dots of the electron-dot-cloud are galaxies
a_plutonium - 25 Nov 2007 19:44 GMT
--- quoting from Wikipedia on BMP ---
[edit] List of Bone Morphogenetic Proteins

BMP Known functions Gene Locus
BMP1 *BMP1 does not belong to the TGF-β family of proteins. It is a
metalloprotease that acts on procollagen I, II, and III. It is
involved in cartilage development. Chromosome: 8; Location: 8p21
BMP2 Acts as a disulfide-linked homodimer and induces bone and
cartilage formation. It is a candidate as a retinoid mediator. Plays a
key role in osteoblast differentiation. Chromosome: 20; Location:
20p12
BMP3 Induces bone formation Chromosome: 14; Location: 14p22
BMP4 Regulates the formation of teeth, limbs and bone from mesoderm.
It also plays a role in fracture repair. Chromosome: 14; Location:
14q22-q23
BMP5 Performs functions in cartilage development. Chromosome: 6;
Location: 6p12.1
BMP6 Plays a role in joint integrity in adults. Chromosome: 6;
Location: 6p12.1
BMP7 Plays a key role in osteoblast differentiation. It also induces
the production of SMAD1. Also key in renal development and repair.
Chromosome: 20; Location: 20q13
BMP8a Involved in bone and cartilage development Chromosome: 1;
Location: 1p35-p32
BMP8b Expressed in the hippocampus. Chromosome: 1; Location: 1p35-p32
BMP10 May play a role in the trabeculation of the embryonic heart.
Chromosome: 2; Location: 2p14
BMP15 May play a role in oocyte and follicular development.
Chromosome: X; Location: Xp11.2

--- end quoting Wikipedia ---

What I am looking for is that the difference between Humans and Apes
is a genetics for
Throwing abilities. Humans have that genetics which apes do not. I am
looking for the genes
for Throwing and I may have to expand the chromosomes not confined to
just chromosome 2.

So I want a protein that is unique to the excellent throwing ability
found in the Human species
and not found in apes.

In order to be the "best thrower" in the world, I suspect the proteins
for ligaments should be
near the top in my search. And of the arm bones the elbow region
should be the vital region
in throwing for it is the first region that is damaged when baseball
pitchers start to become
unhealthy. So the elbow region is the "weak point in the throwing-
system" so I should focus
on what genetics of the human elbow are unique to humanity and not
found in apes.

Now I do not see a BMP above that focuses or is concentrated or is
dense to the elbow region
but maybe someone has found such a protein that is dense to the elbow
region of humanity.

Archimedes Plutonium
www.iw.net/~a_plutonium
whole entire Universe is just one big atom
where dots of the electron-dot-cloud are galaxies

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