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Medical Forum / General / General / August 2007

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Mechanical properties of heart plaque

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Stem sells - 23 Aug 2007 19:08 GMT
Is this stuff brittle or soft?

Why not somehow melt, physically crack, or scrape this out of the
arteries/veins with micro-robots?
malibu - 23 Aug 2007 19:27 GMT
> Is this stuff brittle or soft?
>
> Why not somehow melt, physically crack, or scrape this out of the
> arteries/veins with micro-robots?

It's hard, crystallized Cholesterol
and actually replaces tissue between the
inside and outside of the vessel.

55% of it contains Herpesvirus.
Herpesvirus has been shown to deposit
crystallized Cholesterol in plaque form in
cultured cat cells.

I have found that Herpesvirus can be
discouraged by change of diet to eliminate
Hydrogenated and partially Hydrogenated fats.

Your liver makes your own Cholesterol. You
don't need the cow's.

John
Greg Neill - 23 Aug 2007 21:13 GMT
> Is this stuff brittle or soft?
>
> Why not somehow melt, physically crack, or scrape this out of the
> arteries/veins with micro-robots?

Good idea.  Where's it going to go to from there?
malibu - 23 Aug 2007 21:25 GMT
> > Is this stuff brittle or soft?
>
> > Why not somehow melt, physically crack, or scrape this out of the
> > arteries/veins with micro-robots?
>
> Good idea.  Where's it going to go to from there?

They already use a balloon to expand the artery
and break the constricting circle
of plaque *within* the arterial wall.
Some of it is resorbed, I imagine, and the rest stays
right where it is.
The endometrium (inner wall) of the artery remains
unbroken and simply stretches.
The plaque does not enter the blood stream.
John
Andy Resnick - 23 Aug 2007 21:59 GMT
> Is this stuff brittle or soft?
>
> Why not somehow melt, physically crack, or scrape this out of the
> arteries/veins with micro-robots?

Arterial plaque is essentially a clot.  What happens to the clot once
it's scraped off the aterial walls?  Sending it to the lungs is bad.
Sending it to the brain is bad.  That's why stents and balloons are used.

Signature

Andrew Resnick, Ph.D.
Department of Physiology and Biophysics
Case Western Reserve University

PD - 23 Aug 2007 23:25 GMT
> Is this stuff brittle or soft?
>
> Why not somehow melt, physically crack, or scrape this out of the
> arteries/veins with micro-robots?

One big problem with arterial plaque is the chance that it will
spontaneously crack or fall off the wall of the artery, causing a
stroke or a pulmonary or cardiac thrombosis. You are suggesting
initiating that on purpose.

That's a little like treating Alzheimer's with a lobotomy.

PD
 
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