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Medical Forum / General / General / July 2007

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strep throat treatment

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osutool@gmail.com - 14 Jul 2007 03:24 GMT
I just found out from a nurse while attempting to donate blood that I
appear to have strep throat (a bunch of white spots just formed on my
tonsils and a fever has begun). Having no insurance or way to pay for
a doctor visit, what is the best way to deal with strep? Is plenty of
fluids, vitamins, and sleep good enough?
JEDilworth - 14 Jul 2007 06:43 GMT
If you do not treat this with penicillin, which is prescription and
cheap (many pharmacies in our area are offering this for free with a
prescription) you risk having a possible kidney problem in the future if
it is Group A beta strep. There are other strep groups that can give you
the symptoms you describe, and make you feel lousy, but won't give you
the kidney scenario. Unfortunately a culture or rapid test needs to be
performed in order to tell.

I would investigate your local Health Department - they have a lot of
free clinics. Do this ASAP.

Judy Dilworth, M.T. (ASCP)
Microbiology

>I just found out from a nurse while attempting to donate blood that I
> appear to have strep throat (a bunch of white spots just formed on my
> tonsils and a fever has begun). Having no insurance or way to pay for
> a doctor visit, what is the best way to deal with strep? Is plenty of
> fluids, vitamins, and sleep good enough?
David Rind - 15 Jul 2007 02:18 GMT
> If you do not treat this with penicillin, which is prescription and
> cheap (many pharmacies in our area are offering this for free with a
[quoted text clipped - 15 lines]
>> a doctor visit, what is the best way to deal with strep? Is plenty of
>> fluids, vitamins, and sleep good enough?

1) It's hard to be sure clinically that this is strep. Viral sore
throats can look like this too.

2) I don't know of any evidence that antibiotic therapy reduces the
likelihood of kidney problems (PSGN) after strep throat.

3) The main argument for treating strep with antibiotics is to prevent
rheumatic fever, though this is a rare complication these days.

4) Antibiotics might also decrease the risk of someone with a strep
throat developing a peritonsillar abscess.

Signature

David Rind
drind@caregroup.harvard.edu

JEDilworth - 15 Jul 2007 05:44 GMT
http://dentalresource.org/topic56scarletfever.html

Glomerulonephritis can also be a problem with Group A beta strep
infections that lead to scarlet fever, in addition to rheumatic fever.

Yes, it is difficult to determine if this is viral or streptococcal over
the internet.

Judy Dilworth, M.T. (ASCP)
Microbiology

> 1) It's hard to be sure clinically that this is strep. Viral sore
> throats can look like this too.
[quoted text clipped - 7 lines]
> 4) Antibiotics might also decrease the risk of someone with a strep
> throat developing a peritonsillar abscess.
David Rind - 15 Jul 2007 14:26 GMT
>> 1) It's hard to be sure clinically that this is strep. Viral sore
>> throats can look like this too.
[quoted text clipped - 7 lines]
>> 4) Antibiotics might also decrease the risk of someone with a strep
>> throat developing a peritonsillar abscess.

> http://dentalresource.org/topic56scarletfever.html
>
[quoted text clipped - 6 lines]
> Judy Dilworth, M.T. (ASCP)
> Microbiology

This would be easier to follow if you didn't top post. I'll cut and
paste to move my earlier post to the right place.

I didn't say that strep can't cause glomerulonephritis ("PSGN" in my
post above is "post-streptococcal glomerulonephritis). I said that I
don't know of any evidence that treating strep with antibiotics reduces
the risk of this complication. I could have said it more strongly: there
is no good evidence that treating strep throat helps prevent PSGN.

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David Rind
drind@caregroup.harvard.edu

JEDilworth - 16 Jul 2007 04:58 GMT
Fine. Whatever.

Judy Dilworth, M.T. (ASCP)
Microbiology
David Rind - 16 Jul 2007 11:52 GMT
> Fine. Whatever.
>
> Judy Dilworth, M.T. (ASCP)
> Microbiology

I'm assuming that was in response to my post.

When I post misinformation to sci.med, I hope someone who spots that
what I wrote was wrong will post a correction.

What are you hoping people will do when you post misinformation?

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David Rind
drind@caregroup.harvard.edu

Robert1 - 16 Jul 2007 18:40 GMT
>  > "David Rind" <dr...@caregroup.harvard.edu> wrote in message
>  >news:f7bsma$etb$1@reader2.panix.com...
[quoted text clipped - 37 lines]
> David Rind
> dr...@caregroup.harvard.edu

It is basically implied and don't know of any direct studies except
this animal model. Anything new studies out there?

1: Acta Pathol Microbiol Immunol Scand [C]. 1983 Aug;91(4):271-81.
LinkOut
Effect of early penicillin treatment on the development of
experimental poststreptococcal glomerulonephritis.Bergholm AM, Holm
SE.
A newly developed experimental model in which poststreptococcal
glomerulonephritis (PSGN) was established in rabbits utilizing viable
group A streptococci, was used to study the possibility of hindering
the development of renal disease by early penicillin treatment. The
development of renal injury was followed by proteinuria, creatinine
clearance, histological and immunological examinations of the kidneys.
Therapy within the first 3 days of infection with i.m. pc-G prevented
the nephritic process.

PMID: 6356782 [PubMed - indexed for MEDLINE]

1: Monatsschr Kinderheilkd. 1992 Aug;140(8):490-2. LinkOut
[Has post-streptococcal glomerulonephritis disappeared?][Article in
German]
Latta K, Ehrich JH, Brodehl J.
Kinderklinik Medizinischen Hochschule Hannover.

We report on 21 children with poststreptococcal glomerulonephritis
(PSGN). The diagnosis was based on clinical and laboratory criteria.
19/21 had a clinically apparent throat infection initially, but only 6
received antibiotic treatment. Initial symptoms were: macrohematuria
(20/21), edema (10/21), arterial hypertension (6/21), reduced
creatinine-clearance (11/21), and proteinuria (18/21). No Patient was
dialyzed. After an interval of 0.3 to 25 months 19 children are
asymptomatic. All patients have normal creatinine-clearances; none is
hypertensive. The present data show that PSGN has not disappeared in
Mid-Europe. Remarkable acute disturbances occurred, which healed in
almost all cases. The importance of accurate bacteriologic diagnosis
and adequate therapy is emphasized.

PMID: 1435810 [PubMed - indexed for MEDLINE]
David Rind - 17 Jul 2007 01:48 GMT
>>I didn't say that strep can't cause glomerulonephritis ("PSGN" in my
>>post above is "post-streptococcal glomerulonephritis). I said that I
[quoted text clipped - 45 lines]
>
> PMID: 1435810 [PubMed - indexed for MEDLINE]

I don't have access to the rabbit study, but would wonder about the
timing of the infection and the treatment. There are lots of
complications of diseases that you can prevent in an animal model if you
start treatment at the moment of injury or infection, but that don't
translate to humans where treatment can't start until the infection
becomes clinically apparent.

No one is likely to perform an RCT since we treat strep throat to
prevent RF and to speed recovery.

The OP was trying to avoid seeing a doctor for an illness that may or
may not have been strep. While everyone would advise him that it's safer
to see a doctor, I don't think anyone would think that it's likely to go
badly if he doesn't. If he really has strep, he's at some small risk of
developing RF if he doesn't get treated. His risk of PSGN is quite low,
and we really don't know that we can modify it at all by treating him.

Signature

David Rind
drind@caregroup.harvard.edu

 
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