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Medical Forum / General / General / June 2007Help treat ataxia
Dear All, This is from Beijing. My mother got a rare serious disease, gradually worse by days , the following is the detail: Female, age of 60 Progression of the Disease: astasia from Apr 6th Apr. 15: left lower extremities anesthesia, instability of gait, gradually unable to walk May 10: ataxia, left FNT positive May 15: difficult to keep a sitting position June 8: Urination difficulty During the past two months, the symptom of ataxia that involved the body and all extremities developed gradually, more severe in the left side of the body. The patient also suffered from diplopia, blurred vision, dizziness, mild headache et al. the symptoms progressed gradually and become aggravated with the time going on. Physical Examination: horizontal nystagmus anarthria FNT postitive roberg positive alternate motion of left hand postive heel-knee-tib test positive Head mra: Normal (Apr 29) Head mri (contrast): lacunar infarction of corona radiata tumor marker : Normal TCD: Normal Blood Rheology: Normal Lung ct: Normal Abdomen B-ultrasound: Normal Mammary gland B-ultrasound: Normal Vagina B-ultrasound: Normal TCT: Normal Electromyography and Evoked Potential：Normal PET: slightly enhancement at up middle abdominal region, no abnormal were found at CT examination. Cerebrospinal Fluid: CSF Cell Count：2*106/L White blood cell count: 0 IgG: 4.10mg/dl IgM: 0.69mg/dl IgA: 1.11mg/dl Protein: 39 Chloride: 123 Glucose: 62 Oligoclonal band: Negative IgG 24h Synthesis Rate: -0.941 MBP：0.84 Hu Antibody: Negative Yo Antibody: Negative Ri Antibody: Negative Past Clinical History: 2got Herpes zoster on Dec. 23, 2006 , recovered in March 2007. Family Clinical History: Mother：Died of stomach cancer at her sixties Older Sister 1：Died of liver cancer at her sixties Older sister 2: Parkinson Brother: Diabetes for 15 years Treatment: Apr. 19- May 10: Sodium Ozagrel, Danhong (No effect) May 26 – May 30: Human Immunoglobulin 30g/day, 5 days (No effect) Diagnosis: no diagnosis Dear friends, please provide some advises about the diagnosis or treatment, if you can. thanks a lot. Email: amberiris@sina.com.cn On Jun 26, 3:10 am, "travellingf...@googlemail.com" Mother：Died of stomach cancer at her sixties Older Sister 1：Died of liver cancer at her sixties Older sister 2: Parkinson Brother: Diabetes for 15 years << I would look into elevated iron levels .. linked to cancer , Parkinsons and diabetes. Type in iron excess , iron overload , hemochromatosis .. Another name for it is .. superficial siderosis .. -------------------------------------------------------- Journal of Clinical Neuroscience Volume 12, Issue 7, September 2005, Pages 807-808 doi:10.1016/j.jocn.2004.09.011 Copyright © 2005 Elsevier Ltd All rights reserved. Case report A cast-iron guarantee of ataxia and deafness Meena Shingde MB BS, MD Patha, Jonathan Ell MB BS, FRACPb and Roger Pamphlett MD ChB, FRACP, FRCPatha, , aDepartment of Pathology, The University of Sydney bInstitute of Clinical Neurosciences, Royal Prince Alfred Hospital; Sydney, Australia Received 16 August 2004; accepted 2 September 2004. Available online 29 September 2005. Summary Superficial siderosis of the central nervous system (CNS) is a rare condition that is thought to be caused by repeated subarachnoid haemorrhages. The major clinical features are progressive bilateral hearing loss, cerebellar ataxia and pyramidal dysfunction. Ante-mortem diagnosis is now possible due to MRI and post mortem reports of this condition are becoming rare. Despite the occurrence of typical clinical features the diagnosis is often missed during life if CT scanning alone is performed. We describe a case of superficial siderosis of the CNS with clinical and post mortem findings as a reminder of this unusual condition. Keywords: superficial siderosis; iron; ataxia; deafness Correspondence to: R. Pamphlett, Department of Pathology D06, The University of Sydney, NSW 2006. Tel.: +61 2 9351 3318; Fax: +61 2 9351 3429 Journal of Clinical Neuroscience Volume 12, Issue 7, September 2005, Pages 807-808 Good luck .. Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk |
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