"autoimmune, neurologic or blood disorders. Lupus, polycythemia vera"
<<

"Erythromelalgia is not caused by increased red blood cell production
in lupus or multiple sclerosis" ..

Put a few articles UP with your .. evaluation .. or stfu ..

Pretty simple stuff ..

Put up .. or .. shut .. up ..

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://tinyurl.com/634q5a

Man Is A Herbivore!
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DEAD PEOPLE WALKING
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 India with low meat usage has among the highest rate of them. <<

This is the study which you seem to have a problem with
understanding ..

"Asians and Pacific Islanders have high levels of iron in the blood"

The Asian / Pacific people have the highest iron levels ..

IF .. and it seems you .. are .. INTENT on 'discovering WHY' ..
Indians have such a high iron level and such a high death rate .. you
should get on it ..

BE ... cause .. if you haven't understood by NOW .. my stance IS ..
those with high iron will manifest disease at a high rate ..
specifically diabetes.

Now diabetes is very high in India .. and they have high iron
levels ..

Now go discover WHY .. they DO .. have high iron levels ..

Let me save you some time .. thalassemia ..

----------------

Hemochromatosis: "Surprising" Findings About Iron OverloadUAB and
international scientists studying iron-overload disorders have made
the unexpected discovery that Asians and Pacific Islanders have the
highest levels of iron in their blood of all racial/ethnic groups who
were screened.

Individuals who develop hemochromatosis/iron overload absorb an
excessive amount of iron from food and supplements ingested. The
abnormality affects many people worldwide, is prevalent in the South,
and sometimes causes organ damage when severe iron deposition occurs
due to inadequate control of iron absorption by the small intestine.

The first major report of findings in the five-year, 100,000-person
study was published in The New England Journal of Medicine (NEJM),
April 28. The University of Alabama at Birmingham received $3.1
million of study funds to screen 20,000 people for the group of
disorders called hemochromatosis and iron overload.

Ronald T. Acton, PhD, professor of microbiology and director of the
UAB Immunogenetics Program, is principal investigator for the
Birmingham Field Center that did the screening. James C. Barton, MD,
director of the Southern Iron Disorders Center and UAB clinical
professor of medicine, is co-principal investigator. They exceeded the
goal of screening 10,000 African-Americans and 10,000 whites for blood
iron levels or the presence of mutations in a gene, called the HFE
gene, which evidence suggests regulates iron absorption.

“Hemochromatosis and iron overload are easily treatable if diagnosed
early, but the simple blood test that could detect these conditions is
not performed as part of routine medical exams,” said Acton. Delaying
treatment — the weekly removal of a pint of blood by phlebotomy — can
permit the progressive accumulation of iron deposits in target organs
that may result in complications such as cirrhosis of the liver, liver
cancer, arthritis, diabetes, impotence and heart failure.

“The finding that Asians and Pacific Islanders have high levels of
iron in the blood is surprising because they also have the lowest
prevalence of the particular gene mutation that is found in Caucasians
with the typical form of hemochromatosis,” he said. “This may mean
that the Asians and Pacific Islanders have a different genetic
mutation that has not yet been discovered, or that they do not, for
some reason, develop hemochromatosis/iron overload despite their high
blood levels of iron.”

He said that the NEJM paper is the first report from analysis of the
massive data arising from the study, called the Hemochromatosis and
Iron Overload Screening (HEIRS) Study. The study is funded by the
National Heart, Lung and Blood Institute and the National Human Genome
Research Institute.

The other HEIRS Study Field Centers were located at University of
California, Irvine; London Health Sciences Centre, Ontario, Canada;
Howard University, Washington, DC; and Kaiser Permanente Center for
Health Research (Oregon and Hawaii). Wake Forest University in Winston-
Salem, NC coordinated the Study, and the Study’s Central Laboratory is
located at the University of Minnesota in Minneapolis.

At the beginning of the study in 2000, it was known that most cases of
hemochromatosis in Caucasians resulted from common mutations in the
HFE gene, first discovered in 1996. At that time, little was known
about the causes of iron overload in other racial/ethnic groups.

Major findings of the study include:
* Caucasians had the highest prevalence of persons who had two copies
of the C282Y mutation of the HFE gene (4.4 per 1,000 people).

* Prevalence of two copies of the C282Y mutation of the HFE gene in
other racial/ethnic groups were: Native Americans (1.1 per 1,000),
Hispanics (2.7 per 10,000), African-Americans (1.4 per 10,000),
Pacific Islanders (1.2 per 10,000) and Asians (3.9 per 10 million).

* Most participants who had two copies of the C282Y mutation of the
HFE gene also had elevated levels of iron in their blood.

* Men who had two copies of the C282Y mutation of the HFE gene were
more likely to report a history of liver disease than participants
without HFE mutations.

“Our findings in Caucasians confirm reports from previous smaller
studies,” said Acton. “Our findings in non-Caucasians help everyone
understand the prevalence of these conditions in other racial/ethnic
groups.”

He added that many white Alabamians have Celtic origins, with some
counties reporting Irish ancestry in 17% of the population. “The
hemochromatosis C282Y mutation is thought to have occurred among
Celtic or Scandinavian populations 1,500 to 3,000 years ago, and the
mutation may have helped them survive iron-poor diets.”

Hemochromatosis or iron overload occur in 0.3-0.5% of white persons of
northern, central, and western European descent. In fact, a health-
screening program conducted by Barton and Acton at an Alabama forest
products mill detected the disorder in 0.39% of all white
participants, and 0.53% of white men.

Acton and Barton said they hope that results of the study will prompt
more primary care physicians to consider hemochromatosis and iron
overload as a diagnosis. Nationwide studies indicate it takes an
average of 9 years and three physicians to obtain a correct diagnosis,
partly because physicians incorrectly believe that such disorders are
rare, or that they affect only older men. A previous UAB study found
that primary care physicians provided fewer than 70% correct responses
about screening at-risk populations for hemochromatosis, iron
overload, and associated abnormalities.

As the HEIRS Study shows, iron overload was mistakenly believed to be
a disorder that is limited to Caucasians, said Acton. He, Barton, and
others have begun studying the role of iron overload and HFE mutations
in the development of type 2 diabetes in persons of various racial/
ethnic groups.

Media Contact:
Hank Black
(205) 934-8938
E-mail: hblack@uab.edu

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://tinyurl.com/634q5a

Man Is A Herbivore!
http://tinyurl.com/4rq595

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk