Medical Forum / Diseases and Disorders / Lupus / June 2008
Most Patients Die Of It
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ironjustice - 25 Jun 2008 03:15 GMT Thrombotic thrombocytopenic purpura: 2008 updlate Crowther MA, George JN Cleve Clin J Med 2008 May; 75(5):369-75.
Thrombotic thrombocytopenic purpura (TTP) is a spectrum of syndromes characterized by thrombocytopenia and microangiopathic hemolytic anemia, manifested by an elevated blood lactate dehydrogenase (LDH) concentration and red blood cell fragments. It classically occurs in patients with a hereditary or acquired lack of ADAMTS13, a metalloproteinase that cleaves large multimers of von Willebrand factor. Other TTP-like syndromes, including TTP associated with pregnancy, organ transplantation, and certain medications, likely have different underlying causes and may require different treatment. Unless TTP is recognized promptly and treated aggressively, most patients die of it. Cleveland Clinic journal of medicine [Cleve Clin J Med] --------------------------------------------------------------------------------
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Citizen Jimserac - 25 Jun 2008 12:57 GMT > Thrombotic thrombocytopenic purpura: 2008 updlate > Crowther MA, George JN [quoted text clipped - 23 lines] > > DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk The following case is reported in "The Patient, Not the Cure" subtitled "The Challenge of Homeopathy" by Dr. Margery Blackie, former physician to Queen Elizabeth: (page 174) comments on a child with purpura: "The patient had seen a specialist from one of the teaching hospitals and was obviously dying. He had a poor blood condition together with a very low platelet count and when seen he was bleeding from everywhere - the nose, mouth, bladder, bowell and was bruised from head to foot. He was given Crotalus horridus (rattle snake) and he did very well indeed. His platelet count went up from a very dangerous level to nearly normal within a few days and he began to sleep well. He was, therefore, out of danger within a short time. He was sent to hospital for a blood transfusion for his consequent anaemia. The consultant who had seen him previously and said he was dying pointed him out to the students as an examle of spontaneous cure which cannot be accounted for, although he new full well he had had a Homeopathic snake venom as a remedy."
Citizen Jimserac
ironjustice - 25 Jun 2008 16:07 GMT On Jun 25, 4:57 am, Citizen Jimserac <Jimse...@gmail.com> wrote:Homeopathic snake venom as a remedy <<
If one knows what snake venom does .. then this gives credence to homeopathy ..
Snake venom causes .. hemolysis ..
Purpura .. is .. hemolysis ..
Like cures .. like ..
Who loves ya. Tom
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Man Is A Herbivore! http://tinyurl.com/4rq595
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> > Thrombotic thrombocytopenic purpura: 2008 updlate > > Crowther MA, George JN [quoted text clipped - 49 lines] > > - Show quoted text - Citizen Jimserac - 26 Jun 2008 11:58 GMT > On Jun 25, 4:57 am, CitizenJimserac<Jimse...@gmail.com> > wrote:Homeopathic snake venom as a remedy << [quoted text clipped - 70 lines] > > > - Show quoted text - Indeed!
Thanks Citizen Jimserac
Hawki63@sbcglobal.net - 25 Jun 2008 17:52 GMT "most" patients do not die of it
many spontaneous go into remission
pool water or not
>> Thrombotic thrombocytopenic purpura: 2008 updlate >> Crowther MA, George JN [quoted text clipped - 47 lines] > > Citizen Jimserac ironjustice - 26 Jun 2008 02:03 GMT On Jun 25, 9:52 am, <Hawk...@sbcglobal.net> wrote: snip <<
Thrombotic thrombocytopenic purpura: 2008 updlate Crowther MA, George JN Cleve Clin J Med 2008 May; 75(5):369-75.
Thrombotic thrombocytopenic purpura (TTP) is a spectrum of syndromes characterized by thrombocytopenia and microangiopathic hemolytic anemia, manifested by an elevated blood lactate dehydrogenase (LDH) concentration and red blood cell fragments. It classically occurs in patients with a hereditary or acquired lack of ADAMTS13, a metalloproteinase that cleaves large multimers of von Willebrand factor. Other TTP-like syndromes, including TTP associated with pregnancy, organ transplantation, and certain medications, likely have different underlying causes and may require different treatment. Unless TTP is recognized promptly and treated aggressively, most patients die of it. Cleveland Clinic journal of medicine [Cleve Clin J Med] --------------------------------------------------------------------------------
Who loves ya. Tom
Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh
Man Is A Herbivore! http://tinyurl.com/4rq595
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> >> Thrombotic thrombocytopenic purpura: 2008 updlate > >> Crowther MA, George JN [quoted text clipped - 49 lines] > > - Show quoted text - Citizen Jimserac - 26 Jun 2008 12:04 GMT On Jun 25, 12:52 pm, <Hawk...@sbcglobal.net> wrote:
> "most" patients do not die of it > [quoted text clipped - 57 lines] > > > CitizenJimserac "Spontaneous Remission" is not an explanation it is an excuse, a rationalization, a descent into superstition as well as pathetic denialism.
SOMETHING enabled the child to survive. You may disagree that it was the Homeopathic remedy, (even though the evidence is staring you in the face) but you MUST agree that something was involved in the causality of the cure.
From the symptoms described and the fact that the standard medical doctor had given up the child for dead, I suggest you begin to entertain the idea that the Homeopathic remedy, with NO atoms of crotalus horridus in it, was the proximal cause of the child's cure.
Citizen Jimserac
Hawki63@sbcglobal.net - 26 Jun 2008 17:57 GMT > On Jun 25, 12:52 pm, <Hawk...@sbcglobal.net> wrote: >> "most" patients do not die of it [quoted text clipped - 65 lines] > > SOMETHING enabled the child to survive. it is more likely that the child was given plasmapheresis....which gives about a 75% chance of "spontaneous remission".....tho yes it can recur
> You may disagree that it was the Homeopathic > remedy, (even though the evidence is staring [quoted text clipped - 9 lines] > crotalus horridus in it, was the proximal > cause of the child's cure. snake venom will not cure ttp
> Citizen Jimserac ironjustice - 26 Jun 2008 23:30 GMT On Jun 26, 9:57 am, <Hawk...@sbcglobal.net> wrote:it is more likely that the child was given plasmapheresis....which gives about a 75% chance of "spontaneous remission" .. <<
One might consider this to be .. NOT .. spontaneous .
Spontaneous means remission without known **reason**.
Plasmapheresis is KNOWN to cause remission.
The chances of the person receiving plasmapheresis are very low when one considers everyone in the **world**.
One will be better served in developed countries but in countries where there is very little health care .. spontaneous recovery is all but non-existent because .. ? .. no plasmapheresis ..
Sooo .. plasmapheresis is the treatment and NOT .. "spontaneous recovery" ..
Try to get plasmapheresis when you can't even get near a hospital with power.
IF someone from the underdeveloped countries were to be cured without any intervention then that is .. spontaneous ..
Who loves ya. Tom
Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh
Man Is A Herbivore! http://tinyurl.com/4rq595
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> > On Jun 25, 12:52 pm, <Hawk...@sbcglobal.net> wrote: > >> "most" patients do not die of it [quoted text clipped - 90 lines] > > - Show quoted text - Citizen Jimserac - 27 Jun 2008 13:20 GMT On Jun 26, 12:57 pm, <Hawk...@sbcglobal.net> wrote:
> "CitizenJimserac" <Jimse...@gmail.com> wrote in message > [quoted text clipped - 90 lines] > > > CitizenJimserac I can assure you, Dr. Margery Blackie, former physician to the Queen of England, was not lying. The child was given a Homepathic remedy, crotalus horridus, and survived because of it.
You can chose to ignore this, pretend it did not happen, or resort to the rationalization of spontaneous remission.
Citizen Jimserac
D. C. Sessions - 27 Jun 2008 13:46 GMT > I can assure you, Dr. Margery Blackie, > former physician to the Queen of England, > was not lying. The child was > given a Homepathic remedy, crotalus horridus, > and survived because of it. Two out of three ain't bad.
| "Ridicule is the only weapon which can be used against | | unintelligible propositions. Ideas must be distinct | | before reason can act on them" -- Thomas Jefferson | +-------- D. C. Sessions <dcs@lumbercartel.com> ---------+
ironjustice - 26 Jun 2008 02:29 GMT On Jun 24, 7:15 pm, ironjustice <teamtan...@hotmail.com> wrote:Thrombotic thrombocytopenic purpura <<
"TTP in association with SLE appears to be underdiagnosed"
Vol. 115, No. 1-2, 2006 Original Paper
Thrombotic Thrombocytopenic Purpura Associated with Systemic Lupus Erythematosus Aamer Aleem, Saleh Al-Sugair
Department of Medicine, Division of aHematology/Oncology and bRheumatology, College of Medicine and King Khalid University Hospital, Riyadh, Saudi Arabia
Address of Corresponding Author
Acta Haematol 2006;115:68-73 (DOI: 10.1159/000089469) Abstract
Thrombotic thrombocytopenic purpura (TTP) occurring in patients with systemic lupus erythematosus (SLE) is rare and can be difficult to diagnose because of overlapping features of the two disorders. The aim of this study is to further characterize this uncommon association in terms of presenting features, diagnostic difficulties and treatment outcome. This is the largest series from a single centre with 6 patients diagnosed over a 6-year period. Two thirds of the patients had a simultaneous diagnosis of TTP and SLE. Half of the patients had a positive Coombs test along with clear features of TTP. Five patients received plasmapheresis as initial treatment while 1 patient received plasma infusions only. Four out of 5 patients responded to plasmapheresis and only 1 patient required cytotoxic therapy. TTP in association with SLE appears to be underdiagnosed and a positive Coombs test is not against the diagnosis of TTP in this setting. Most of the patients respond well to plasmapheresis. In case of a poor response, cytotoxic drugs should be considered early.
Copyright © 2006 S. Karger AG, Basel
--------------------------------------------------------------------------------
Author Contacts
Dr. A. Aleem Department of Medicine (38), King Khalid University Hospital PO Box 7805 Riyadh 11472 (Saudi Arabia) Tel. +966 1 467 1771, Fax +966 1 467 9487, E-Mail aameraleem@hotmail.com
© 2008 S. Karger AG, Basel
Who loves ya. Tom
Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh
Man Is A Herbivore! http://tinyurl.com/4rq595
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> Thrombotic thrombocytopenic purpura: 2008 updlate > Crowther MA, George JN [quoted text clipped - 23 lines] > > DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk ironjustice - 27 Jun 2008 03:43 GMT plasmapheresis <<
"Plasmapheresis alternative to haemodilution"
Here they COMPARE plasmapheresis TO hemodilution.
Hemodilution is called bloodletting by some.
Minerva Anestesiol. 1995 Jul-Aug;61(7-8):293-7.Links [Plasmapheresis and intraoperative hemodilution. Comparison of 2 methods][Article in Italian]
Sonzogni V, Bellavita P, Aceti M, Cossolini M, Lorini L. Secondo Servizio Anestesia e Rianimazione, Ospedali Riuniti, Bergamo.
Fifty patients undergoing cardiac surgery suffering from coronary artery disease and valvular incompetence or stenosis, were randomly divided into two groups of 25 patients to compare the plasmapheresis effects on bleeding, transfusion requirements, economicity and paramedical staff compliance versus intraoperative autotransfusion. Standardized anesthetics, perfusion, and surgical techniques were used. We used plasmapheresis with cell saver and haemodilution with bypass ultrafiltration. Platelet counts, haemoglobin concentration, haematocrit, fibrinogen, bleeding times were evaluated at fixed times for the patients on plasmapheresis and after surgical homologous transfusion. It was that these parameters did not change significantly in the two groups. Intraoperative plasmapheresis is more expensive and less accepted into an operating room than autotransfusion. Intraoperative plasmapheresis will be a good alternative to haemodilution for selected patients.
PMID: 8948740 [PubMed - indexed for MEDLINE]
Who loves ya. Tom
Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh
Man Is A Herbivore! http://tinyurl.com/4rq595
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> Thrombotic thrombocytopenic purpura: 2008 updlate > Crowther MA, George JN [quoted text clipped - 23 lines] > > DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk
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