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Medical Forum / Diseases and Disorders / Lupus / June 2008Iron In Type 2 Diabetes
The role of iron in type 2 diabetes in humans. Rajpathak SN, Crandall J, Wylie-Rosett J, Kabat GC, Rohan TE, Hu FB Biochim Biophys Acta 2008 May 3. The role of micronutrients in the etiology of type 2 diabetes is not well studied. Several lines of evidence suggest that iron may a role in the pathogenesis of type 2 diabetes. Iron is a strong pro-oxidant and high body iron levels are associated with increased level of oxidative stress that may elevate the risk of type 2 diabetes. Several epidemiological studies have reported a positive association between high body iron levels, as measured by circulating ferritin level, and the risk of type 2 diabetes and of other insulin resistance states such as the metabolic syndrome, gestational diabetes and polycystic ovarian syndrome. In addition, increased dietary intake of iron, especially that of heme iron, is associated with risk of type 2 diabetes in apparently healthy populations. Results from studies that evaluated the association between genetic mutations related to iron metabolism have been inconsistent. Further, several clinical trials suggest that by phlebotomy induced reduction in body iron levels may improve insulin sensitivity in humans. However, no interventional studies have yet directly evaluated the effect of reducing iron intake or body iron levels on the risk of developing type 2 diabetes. Such studies are required to prove the causal relationship between moderate iron overload and diabetes risk. Biochimica et biophysica acta [Biochim Biophys Acta] -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > The role of iron in type 2 diabetes in humans. > Rajpathak SN, Crandall J, Wylie-Rosett J, Kabat GC, Rohan TE, Hu FB > Biochim Biophys Acta 2008 May 3. snip So what else is new? On Jun 9, 8:01 am, J666 <j...@nowhere.com> wrote:So what else is new? << Explain what you are doing here .. Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > On Mon, 9 Jun 2008 09:53:12 -0500, ironjust...@aol.com wrote > (in article [quoted text clipped - 7 lines] > > So what else is new? > Explain what you are doing here .. Learning from the masters and laughing at the fools. well - since you posted - about diabetes - in multiple groups 'except' diabetes and, while your post may have applicability in a diabetes group, you haven't given a rationale for posting in these 'non' diabetes groups - so: why don't you explain what your post is doing 'here' in these groups? > On Jun 9, 8:01 am, J666 <j...@nowhere.com> wrote:So what else is new? > << [quoted text clipped - 24 lines] > > > > So what else is new? > well - since you posted - about diabetes - in multiple groups 'except' > diabetes [quoted text clipped - 4 lines] > > why don't you explain what your post is doing 'here' in these groups? Perhaps if he is not smart enough to realize that, he is not smart enough to answer. He evidently has a one track, like an iron railroad track, mind that seems to be rusted out. On Jun 9, 12:31 pm, "Paul T. Holland" <pholl...@bellatlantic.net> wrote:why don't you explain what your post is doing 'here' in these groups? << Well at least you admit you .. don't .. know .. Heh .. heh .. One out of three of us is predicted to get .. diabetes. That should cover it .. but just in case .. exactly what group are you posting out .. of .. ? Holland .. could be alot of different groups seeing that you are very near dead .. Huh .. Holland .. Look at the groups posted to and YOU tell .. me .. which of those groups is NOT diabetes .. related. Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > well - since you posted - about diabetes - in multiple groups 'except' > diabetes [quoted text clipped - 37 lines] > > - Show quoted text - > Well at least you admit you .. don't .. know .. > [quoted text clipped - 4 lines] > That should cover it .. but just in case .. exactly what group are you > posting out .. of .. ? Why are you posting diabetes stuff to sci.med.cardiology when there are many diabetes groups - none of which seems to be in the group to which you post. You really cannot be that stupid and are just being a troll, though not a good one. On Jun 9, 3:24 pm, J666 <j...@nowhere.com> wrote:sci.med.cardiology when there are many diabetes groups << I see you didn't look in the diabetes group .. There really is only one worth while in these groups .. Every group I've posted to is related to diabetes .. I could explain .. but I bet they know who you .. are .. Except for .. Holland .. Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > On Mon, 9 Jun 2008 17:15:31 -0500, ironjust...@aol.com wrote > (in article [quoted text clipped - 14 lines] > You really cannot be that stupid and are just being a troll, though not a > good one. > On Jun 9, 3:24 pm, J666 <j...@nowhere.com> wrote:sci.med.cardiology > when there are many diabetes groups << [quoted text clipped - 3 lines] > Every group I've posted to is related to diabetes .. > I could explain .. but I bet they know who you .. are .. OMG you cannot be that dumb to think that this group, SMC, is a worthwhile medical group and you cannot be that dumb and not know that diabetes effects many parts of the body and illnesses. So if there is only one worthwhile group then why bother to post to groups you feel are not worthwhile unless your reason is something other than giving information you feel is valuable. It is good that you stick to iron and not get into other areas. It is good that you stick to iron and not get into other areas. << Like .. religion .. ? Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk On Jun 9, 6:26 pm, I M Portant <""important\"@ important.com"> wrote:SMC > ironjust...@aol.com wrote: > > On Jun 9, 3:24 pm, J666 <j...@nowhere.com> wrote:sci.med.cardiology [quoted text clipped - 14 lines] > > It is good that you stick to iron and not get into other areas. http://special-needs.families.com/blog/when-your-kid-thrives-on-negative-attention When Your Kid THRIVES on Negative Attention by Kristyn Crow My husband and I were having dinner recently with friends, and we began to discuss our similar experiences with having a child who thrives on negative attention. As our friends talked about their situation, we nodded and could definitely relate. We have a child just like theirs-- one who seems to be in trouble all the time, whose noise volume is three decibels louder than everyone else's in the room, and who always wants to cause conflict. This got me thinking. What are the positive aspects of negative attention? Why would any child WANT it? Here's what I came up with: The Positive about the Negative 1. Say my name. It's been said that people love hearing the sound of their own names. When you hear your name spoken aloud, it's a tiny manifestation that you exist. You belong in the world. You're acknowledged. So I imagine that if little Johnny is hearing, "Johnny! Quit that! Johnny! Did you hear me? Johnny! I mean it! Johnny! Stop that NOW! Johnny. . ." then little Johnny is certain to know he's alive. That's a lot of validation. 2. You say tomato, I say tom-ah-to. Conflict is stimulating. Perhaps these kids secretly feel some delight that a little bit of controversy is brewing. Think about it-human beings love debates. On television, we crave the scandals. We like the news programs where two "experts" hash it out. We like to watch presidential candidates squirm in the hot seat. Maybe a little dispute with mom and dad provides some well-needed intellectual stimulation. 3. Power to the people. Provoking others and causing upset is a manifestation of power. If Susie has the ability to get her siblings up in arms, and has ruined or changed the family outing because of her actions, that's a lot of influence she has on her world. In her view, she must truly be an important individual to have so much power. There must be real satisfaction in that. So if negative attention can be desirable, how can we curb a child's intense need for it? It's not the "negative" aspect of the attention that the child really wants, but the attention itself. From the above three examples, we can take the positive desirable elements-recognition, intellectual stimulation, and power-and channel them toward the positive. * Recognition: Try saying your child's name numerous times a day with a positive spin. "Wow, Johnny! You got ready for school today early and even finished your homework! That's terrific!" And "I'm proud of you, Johnny!" Keep it on-point and not too sappy. Notice the good things, and point them out. * Intellectual Stimulation: Try initiating some interesting discussions as you drive around town or make dinner with your child close by. "What do you think about classrooms without desks? Some teachers are thinking about trying that. Do you think you'd like a classroom like that?" Or, "Do you think there'll ever be a female president of the United States?" Actively listen to your son or daughter's opinions. Ask questions. Show interest. * Power: These children might benefit from having a lot of choices to give them a sense of control. "Do you think we should make grilled cheese sandwiches or go out for hamburgers?" "Let's start reading together at night. What book should we start with?" "How would you like to rearrange your bedroom? You can tell me how you'd like it." With many choices available throughout the day, your son or daughter might not need to engage in so many power-struggles. Our friends said they have tried to keep their family interactions as positive as possible on a daily basis, so that negativity doesn't become the norm in their home. We've all seen that negativity can spread and take over a family's way of communicating if parents don't take active steps to break the cycle. > You really cannot be that stupid and are just being a troll, though not a > good one. ! well done > http://special-needs.families.com/blog/when-your-kid-thrives-on-negative-attention > [quoted text clipped - 94 lines] > > You really cannot be that stupid and are just being a troll, though not a > > good one. Hmmm you ask which group Paul responded from because you don't know? Then you just proved you are a spammer in your own text. On Jun 9, 12:31 pm, "Paul T. Holland" <pholl...@bellatlantic.net> wrote:why don't you explain what your post is doing 'here' in these groups? << Well at least you admit you .. don't .. know .. Heh .. heh .. One out of three of us is predicted to get .. diabetes. That should cover it .. but just in case .. exactly what group are you posting out .. of .. ? Holland .. could be alot of different groups seeing that you are very near dead .. Huh .. Holland .. Look at the groups posted to and YOU tell .. me .. which of those groups is NOT diabetes .. related. Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > well - since you posted - about diabetes - in multiple groups 'except' > diabetes [quoted text clipped - 37 lines] > > - Show quoted text - now, now cb - please don't confuse the boy with facts > Hmmm you ask which group Paul responded from because you don't know? > Then you just proved you are a spammer in your own text. [quoted text clipped - 73 lines] > > > > - Show quoted text - Hmmm you ask which group Paul responded from because you don't know? Then you just proved you are a spammer in your own text. << He **specifically** asked "how does it relate to THIS group" .. I said .. "which group would you be referring to sir" .. You have a hard time understanding English .. ? Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > <ironjust...@aol.com> wrote in message > [quoted text clipped - 72 lines] > > - Show quoted text - Looks like old Tommy boy has reading and comprehension problems also LOL If you don't know which group maybe you should stop crossposting your drivel.... On Jun 10, 12:19 pm, "Cheeky Bastard" <InvalidEm...@aol.com> wrote: Hmmm you ask which group Paul responded from because you don't know? Then you just proved you are a spammer in your own text. << He **specifically** asked "how does it relate to THIS group" .. I said .. "which group would you be referring to sir" .. You have a hard time understanding English .. ? Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > <ironjust...@aol.com> wrote in message > [quoted text clipped - 73 lines] > > - Show quoted text - On Jun 10, 8:44 pm, "Cheeky Bastard" <InvalidEm...@aol.com> wrote:maybe you should stop crossposting your drivel.... << Maybe you should stay off my threads .. I asked you pussy fks .. nicely .. to POINT FKG .. out .. which **specific** group you are unsure doesn't .. belong .. And what happens .. ? You act like pussies .. Well I guess my insight is .. still .. intact .. Name a group .. which isn't related to diabetes .. which this thread exists in .. Name it .. or keep your mouth shut on my threads .. you .. pussy .. fk .. Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > Looks like old Tommy boy has reading and comprehension problems also LOL > If you don't know which group maybe you should stop crossposting your [quoted text clipped - 98 lines] > > - Show quoted text - bwahahaha > On Jun 9, 12:31 pm, "Paul T. Holland" <pholl...@bellatlantic.net> > wrote:why don't you explain what your post is doing 'here' in these > groups? << > > Well at least you admit you .. don't .. know .. actually i did not - i asked which group 'you' referred to in your post...which you have not answered...it is, after all, typical of your defensive posture. > Heh .. heh .. found anyone to agree with your sense of humor yet? > One out of three of us is predicted to get .. diabetes. irrelevant to the issue of which group 'you' referred to in your post also irrelevant given the usenet charters of many of the groups you 'did' post to. already stated that it may be relevant to the diabetes group - and no comment given upon the post itself. that however, has nothing to do with your insertion of off-topic posts to groups wherein their charters specifiy topics... as 'you' would perhaps say: heh .. heh .. > That should cover it .. actually since you didn't answer the actual question put to you [please review todetermine just what it is] you haven't covered anything at all you 'have' put forth a specious justification for your original post, but that isn't what was being asked >but just in case .. exactly what group are you > posting out .. of .. ? by not answering the simple and specific question put to you, you haven't earned the the courtesy of being entitled to an answer of same question in return. > Holland .. could be alot of different groups seeing that you are very > near dead .. ah! but i'm not...nor even close - your silly jibes notwithstanding...lololol > Huh .. Holland .. > > Look at the groups posted to and YOU tell .. me .. which of those > groups is NOT diabetes .. related. well now, even 'if' such were within the areas of discussion for any given group charter, not the issue kid - nor the question asked of you do try to track what is asked - as hard as that may be for lyou > Who loves ya. > Tom [quoted text clipped - 49 lines] > > > > - Show quoted text - On Jun 10, 1:07 pm, "Paul T. Holland" <pholl...@bellatlantic.net> wrote:already stated that it may be relevant to the diabetes group - and no > comment given upon the post itself.<< May be related to .. diabetes .. Let me give you some advice .. SINCE you cannot discern whether the post belongs in .. diabetes groups .. I would suspect you would be unable to discern how diabetes relates to cardiology. Sooo .. since you actually KNOW .. nadda .. ABOUT.. **this** thread .. one might think there is no reason for you to POST .. to .. THIS thread .. ? Yep .. Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > bwahahaha > [quoted text clipped - 118 lines] > > - Show quoted text - > SINCE you cannot discern whether the post belongs in .. diabetes > groups .. I would suspect you would be unable to discern how diabetes > relates to cardiology. Discern ...... obviously you are a disciple of Chung and his "scientific" method of discerning. On Jun 10, 3:35 pm, J666 <j...@nowhere.com> wrote:his "scientific" method of discerning. << And .. such as yourself .. fits in there somewhere .. ? Where would such as yourself .. fit .. in .. science .. ? How many different types of bacteria live in sht .. ? Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > On Tue, 10 Jun 2008 15:15:46 -0500, ironjustice wrote > (in article [quoted text clipped - 6 lines] > Discern ...... obviously you are a disciple of Chung and his "scientific" > method of discerning. On Jun 10, 3:35 pm, J666 <j...@nowhere.com> wrote:his "scientific" method of discerning. << >How many different types of bacteria live in sht .. ? Tell us Tom, when did they put you under a microscope so you can know your magic number? CB lol - let's use that 'logic' again tom > On Jun 10, 1:07 pm, "Paul T. Holland" <pholl...@bellatlantic.net> > wrote:already stated that it may be relevant to the diabetes group - > and no > > comment given upon the post itself.<< > > May be related to .. diabetes .. logic dictates that you cannot eliminate the word 'group' from what 'i' wrote unless you are deliberately attempting to change the meaning i compare posting to 'these' groups, vs had you posted in the diab. group... > Let me give you some advice .. and if i were to say: 'no'? [that was, of course, rhetorical humor] > SINCE you cannot discern whether the post belongs in .. diabetes actually tom, that is exactly what i did posit - that it belonged there, not here...unless, that is, you cared to expound upon 'why' you bothered to post to so many unrelated groups who have their own specific topic agenda you see, youngster - that is what you failed to do - give a short, and 'friendly' reason why you did so - instead, you just argue... > groups .. I would suspect you would be unable to discern how diabetes > relates to cardiology. gosh! you only 'suspect? and here 'i' would have thought that you would have remembered from previous contacts with me that i have several generations in my family who are type II i have over 60 years of personal reason to follow the literature, studies, and advances of knowledge re diabetes, vascular interrelationships, and new understandings. you see, it may impact my family directly so the more we learn the healthier they can be. you on the other hand, learn about things only from your singular perspective re iron. you haven't written anything that is your own, is really all that new, nor have you expanded upon the concept that the fe issue is adjunct to the underlying diabetic situation - it's an effect and needs to be addressed, but it's not going to do a durn thing to solve the 'causative' medical condition iron does not create the diabetic - > Sooo .. since you actually KNOW .. nadda .. ABOUT.. **this** thread .. factually i know more about the medical condition, it's genetic and/or behavioral sources, and the combined modalities that are necessary to deal with it than you... and did i mention 'again' that you weren't posting to diabetes, you posted about it to numerous groups with no explanation? tsk, tsk > one might think there is no reason for you to POST .. to .. THIS > thread .. ? i realize that were i not to post in reply, you would find it more comfortable , and you would thus not have to actually explain yourself, but you know what? too bad. not my problem > Yep .. indeed > Who loves ya. > Tom [quoted text clipped - 130 lines] > > > > - Show quoted text - On Jun 10, 3:38 pm, "Paul T. Holland" <pholl...@bellatlantic.net> wrote: snip << Long winded whack stroking himself .. I see you finally answered the question .. Fibromyalgia is the group you have figure is not related to diabetes. Now like I already pointed .. out .. you could not figure **conclusively** / "may belong in diabetes" .. an you figure you CAN figure out whether it belongs in .. fibromyalgia .. Like I said .. you cannot .. evidenced by .. ? The fact you are .. again .. whining how it "doesn't belong and is not related to diabetes" .. Sooo .. let me synopsy what you said .. "diabetes is not related to fibromyalgia" .. You are wrong .. Need proof .. ? Eat me .. Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > lol - let's use that 'logic' again tom > [quoted text clipped - 206 lines] > > - Show quoted text - > On Jun 10, 3:38 pm, "Paul T. Holland" <pholl...@bellatlantic.net> > wrote: snip << [quoted text clipped - 21 lines] > > Eat me .. I guess "eat me" means you lost this one. Go find someone else to bother Eat yourself............. > > On Jun 10, 3:38 pm, "Paul T. Holland" <pholl...@bellatlantic.net> > > wrote: snip << [quoted text clipped - 27 lines] > > Eat yourself............. Don not feed idiots like ironjustice understand the thought, but he's really a hoot when read for actual content. be well paul > Don not feed idiots like ironjustice > understand the thought, but he's really a hoot when read for actual > content. [quoted text clipped - 4 lines] > >> Don not feed idiots like ironjustice But with little change, he is like an iron-ing bored. He does really make an easy target which at least is a pleasant change of pace from Chungie. The 2PDer DIET does seem to ignore iron content. In Japan the legislature is called Diet and not Approach indeed! > > understand the thought, but he's really a hoot when read for actual > > content. [quoted text clipped - 10 lines] > The 2PDer DIET does seem to ignore iron content. In Japan the legislature is > called Diet and not Approach On Jun 11, 4:50 pm, J666 <j...@nowhere.com> wrote: snip<< "How many different kinds of bacteria in sht" Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk I hope somebody some > > understand the thought, but he's really a hoot when read for actual > > content. [quoted text clipped - 10 lines] > The 2PDer DIET does seem to ignore iron content. In Japan the legislature is > called Diet and not Approach On Jun 10, 6:53 pm, Alan <a...@usuk.com> wrote: I guess "eat me" means you lost this one. << Seeing that you .. figure .. "he lost this one" .. means .. ? You share the same empty .. haid .. as Holland .. You don't know the simplest things about fibromyalgia / IE: "diabetes and fibromyalgia are not related" .. but you figure you can attempt to speak to .. my threads .. ? You are stupid .. too stupid for my threads .. whch are **science** based .. Sooo .. stick with making mudpies .. and try to lose some of that .. weight .. Now if YOU would have done the simple search of "fibromyalgia and diabetes" .. I may not have called you a fat slob .. "Clinical association between obesity, diabetes mellitus and fibromyalgia." Fibromyalgia in diabetes mellitus. Tishler M, Smorodin T, Vazina-Amit M, Ramot Y, Koffler M, Fishel B. Department of Medicine 'B' and the Rheumatology Service, Assaf Harofe Medical Center, Zerifin, Israel. tishler@asaf.health.gov.il OBJECTIVE: The aim of this study was to evaluate the prevalence of fibromyalgia (FM) in patients with diabetes mellitus (DM). SUBJECTS: The study included 100 consecutive unselected patients with DM attending our diabetes clinic. Patients were divided into two groups: 45 patients with type 1 diabetes and 55 patients with type 2 diabetes. A group of 50 healthy hospital staff members served as controls. The FM was diagnosed according to the 1990 American College of Rheumatology criteria. Counts of 18 tender points were performed by thumb palpation and assessed by dolorimeter. Routine biochemical tests and levels of HbA(1c) were recorded in each patient. RESULTS: The main outcome measure was the association of FM with DM. Fibromyalgia was diagnosed in 17 patients (17%) with DM and in only one (2%) healthy control ( P=0.008). No differences in patients were noted in the prevalence of FM between type 1 and type 2 diabetes (18.5% vs 15.5%, respectively). Patients with both FM and DM had significantly higher levels of HbA(1c) than DM patients without FM (9.2+/-1.1% vs 6.4+/-1.5%) ( P<0.05). Similarly, the numbers of tender points, pain scores, and the prevalence of sleep disturbances, fatigue, and headaches were higher in this group of patients. A significant correlation was observed between the numbers of tender points and HbA(1c) levels in the DM patients with FM ( r=0.72, P=0.027). CONCLUSION: Fibromyalgia is a common finding in patients with types 1 and 2 diabetes, and its prevalence could be related to control of the disease. As with other diabetes complications, FM might be prevented by improved control of blood glucose levels. PMID: 12756495 [PubMed - indexed for MEDLINE] ---------------------------- Recenti Prog Med. 2003 Apr;94(4):163-5.Links [Prevalence of fibromyalgia in diabetes mellitus and obesity][Article in Italian] Patucchi E, Fatati G, Puxeddu A, Coaccioli S. Clinica Medica e Scuola di Specializzazione in Reumatologia, Università di Perugia, Azienda Ospedaliera Santa Maria, Terni. To determine the prevalence of fibromyalgia in diabetes mellitus and obesity, 121 consecutive patients have been observed: 27 with obesity (6 males and 21 females; mean age 57 years, range 20-57; mean body mass index [BMI] 34); 88 with type 2 diabetes mellitus (T2DM; 40 males and 48 females; mean age 63 years, range 44-78; mean BMI 28.8; mean glycated haemoglobin [HbA1c] in the last year 8.3%); 6 with type 1 diabetes mellitus (T1DM; 2 males and 4 females; mean age 52 years, range 26-76; mean BMI 24.5; mean HbA1c < 7%). An original questionnaire has been proposed (answer yes/not) as follows: 1) chronic (more than 3 months) and diffuse musculoskeletal pain; 2) sleep disturbances; 3) generalized fatigue; 4) paresthesias at the extremities; 5) swollen impression at hands and feet; 6) symptoms referred to irritable bowel syndrome; 7) headache; 8) symptoms change related with environmental climatic variations and/or exercise. A chronic and diffuse musculoskeletal pain has been reported by 62% of patients as well as in 9% of patients 11/18 positive tender points have been documented. In the patients with a BMI less that 26 the diagnosis of fibromyalgia was negative. Our data seem to reveal the presence of a significant clinical association between obesity, diabetes mellitus and fibromyalgia. PMID: 12677786 [PubMed - indexed for MEDLINE] Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > > On Jun 10, 3:38 pm, "Paul T. Holland" <pholl...@bellatlantic.net> > > wrote: snip << [quoted text clipped - 29 lines] > > - Show quoted text - Speaking of eating, and crossposting to alt.med.fibromyalgia, a reminder that 80% of diabetics are obese. But ironboy has no notion about causality. He sees the word "association" and ignores simple (even for him) differences between cause and effect. But he needs to be reminded not to be using the word "pussy" in a bad way. After all, his mother has one, and she's the one paying for him to be able to stay on the internet. Tom needs to get out of the basement, get a job, kiss a girl (or boy, considering the content of some of his posts) and get a life. > On Jun 10, 6:53 pm, Alan <a...@usuk.com> wrote: I guess "eat me" > means you lost this one. << [quoted text clipped - 18 lines] > "Clinical association between obesity, diabetes mellitus and > fibromyalgia." > Speaking of eating, and crossposting to alt.med.fibromyalgia, > a reminder that 80% of diabetics are obese. But ironboy has > no notion about causality. He sees the word "association" and > ignores simple (even for him) differences between cause and effect. A sign of a simpleton. It is really pathetic and funny watching him trying to be like the "big boys." > But he needs to be reminded not to be using the word "pussy" > in a bad way. After all, his mother has one, and she's the one > paying for him to be able to stay on the internet. Tom needs to > get out of the basement, get a job, kiss a girl (or boy, considering > the content of some of his posts) and get a life. Maybe he does not like pussies On Jun 11, 5:25 am, J666 <j...@nowhere.com> wrote:Maybe he does not like pussies << Not too many men .. do .. Write it down .. Remember it .. Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > On Wed, 11 Jun 2008 05:38:01 -0500, Michael B wrote > (in article [quoted text clipped - 15 lines] > > Maybe he does not like pussies On Jun 11, 3:38 am, Michael B <baugh...@bellsouth.net> wrote: snip.<< You got a reason to be on this thread .. lefty .. ? Do ya ..? You got to say .."kissing boys" .. ? Is THAT .. really .. the only reason you are bothering to post to my threads .. lefty .. ? I would've thought maybe the religion end of it .. but I am really seeing a sort of lefty leaning .. in .. you .. Which would make sense with the fibromyalgia end of it .. Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk Heh .. heh .. > Speaking of eating, and crossposting to alt.med.fibromyalgia, > a reminder that 80% of diabetics are obese. But ironboy has [quoted text clipped - 31 lines] > > - Show quoted text - and you post such homophobic thoughts because? > On Jun 11, 3:38 am, Michael B <baugh...@bellsouth.net> wrote: snip.<< > [quoted text clipped - 60 lines] > > > > - Show quoted text - On Jun 11, 2:08 pm, "Paul T. Holland" <pholl...@bellatlantic.net> wrote: long winded whack << Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk 'long winded' to inquire with one sentence about your homophobic postings? 'whack' to question your homophobic comments? then i proudly wear that label... iron justice wrote: > On Jun 11, 2:08 pm, "Paul T. Holland" <pholl...@bellatlantic.net> > wrote: long winded whack << [quoted text clipped - 10 lines] > DEAD PEOPLE WALKING > http://tinyurl.com/zk9fk On Jun 12, 11:19 am, "Paul T. Holland" <pholl...@bellatlantic.net> wrote:long winded whack << Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk The role of iron in type 2 diabetes in humans. Rajpathak SN, Crandall J, Wylie-Rosett J, Kabat GC, Rohan TE, Hu FB Biochim Biophys Acta 2008 May 3. The role of micronutrients in the etiology of type 2 diabetes is not well studied. Several lines of evidence suggest that iron may a role in the pathogenesis of type 2 diabetes. Iron is a strong pro-oxidant and high body iron levels are associated with increased level of oxidative stress that may elevate the risk of type 2 diabetes. Several epidemiological studies have reported a positive association between high body iron levels, as measured by circulating ferritin level, and the risk of type 2 diabetes and of other insulin resistance states such as the metabolic syndrome, gestational diabetes and polycystic ovarian syndrome. In addition, increased dietary intake of iron, especially that of heme iron, is associated with risk of type 2 diabetes in apparently healthy populations. Results from studies that evaluated the association between genetic mutations related to iron metabolism have been inconsistent. Further, several clinical trials suggest that by phlebotomy induced reduction in body iron levels may improve insulin sensitivity in humans. However, no interventional studies have yet directly evaluated the effect of reducing iron intake or body iron levels on the risk of developing type 2 diabetes. Such studies are required to prove the causal relationship between moderate iron overload and diabetes risk. Biochimica et biophysica acta [Biochim Biophys Acta] -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > On Jun 12, 11:19 am, "Paul T. Holland" <pholl...@bellatlantic.net> > wrote:long winded whack << this whack says that your activities resemble: "Homophobia (from Greek homós: one and the same; phóbos: fear, phobia) is a term used to describe irrational fear of, aversion to, or discrimination against homosexuals. It can also mean "irrational fear of, aversion to, or discrimination against homosexuality or homosexuals".[7] Homophobic is the adjective form of this term used to describe the qualities of these characteristics while homophobe is the noun form given as a title to individuals with homophobic characteristics." tell everyone here tom, is it that you are simply the proverbial lout who says and does anything trying to get a rise out his perceived opponant? it that it tom? are you just so crude and petulant not to care when you write those things to and about folks? are you even adult enough to own up to what you write? so often 'you' write to another - how does it 'feel'... well tom, how does it 'feel' when you write slurs, and aspersions - how does it 'feel' to call so many individuals 'lefty' are you smiling when you do it? do you 'feel' superior when you sneeringly use sexuality [whether true or not] as a cudgel and a epithet? or are you a moral runt who won't answer truthfully? > Who loves ya. > Tom [quoted text clipped - 7 lines] > DEAD PEOPLE WALKING > http://tinyurl.com/zk9fk On Jun 12, 2:15 pm, "Paul T. Holland" <pholl...@bellatlantic.net> wrote: long winded whack << The role of iron in type 2 diabetes in humans. Rajpathak SN, Crandall J, Wylie-Rosett J, Kabat GC, Rohan TE, Hu FB Biochim Biophys Acta 2008 May 3. The role of micronutrients in the etiology of type 2 diabetes is not well studied. Several lines of evidence suggest that iron may a role in the pathogenesis of type 2 diabetes. Iron is a strong pro-oxidant and high body iron levels are associated with increased level of oxidative stress that may elevate the risk of type 2 diabetes. Several epidemiological studies have reported a positive association between high body iron levels, as measured by circulating ferritin level, and the risk of type 2 diabetes and of other insulin resistance states such as the metabolic syndrome, gestational diabetes and polycystic ovarian syndrome. In addition, increased dietary intake of iron, especially that of heme iron, is associated with risk of type 2 diabetes in apparently healthy populations. Results from studies that evaluated the association between genetic mutations related to iron metabolism have been inconsistent. Further, several clinical trials suggest that by phlebotomy induced reduction in body iron levels may improve insulin sensitivity in humans. However, no interventional studies have yet directly evaluated the effect of reducing iron intake or body iron levels on the risk of developing type 2 diabetes. Such studies are required to prove the causal relationship between moderate iron overload and diabetes risk. Biochimica et biophysica acta [Biochim Biophys Acta] -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk so, you can't actually rebute anything? [that is of course a rhetorical question] you see tom - that's what discussion, even one that is heated and a dispute, is all about you 'could' be better than that - > On Jun 12, 2:15 pm, "Paul T. Holland" <pholl...@bellatlantic.net> > wrote: long winded whack << [quoted text clipped - 45 lines] > DEAD PEOPLE WALKING > http://tinyurl.com/zk9fk On Jun 13, 2:55 pm, "Paul T. Holland" <pholl...@bellatlantic.net> wrote: long winded whack << The role of iron in type 2 diabetes in humans. Rajpathak SN, Crandall J, Wylie-Rosett J, Kabat GC, Rohan TE, Hu FB Biochim Biophys Acta 2008 May 3. The role of micronutrients in the etiology of type 2 diabetes is not well studied. Several lines of evidence suggest that iron may a role in the pathogenesis of type 2 diabetes. Iron is a strong pro-oxidant and high body iron levels are associated with increased level of oxidative stress that may elevate the risk of type 2 diabetes. Several epidemiological studies have reported a positive association between high body iron levels, as measured by circulating ferritin level, and the risk of type 2 diabetes and of other insulin resistance states such as the metabolic syndrome, gestational diabetes and polycystic ovarian syndrome. In addition, increased dietary intake of iron, especially that of heme iron, is associated with risk of type 2 diabetes in apparently healthy populations. Results from studies that evaluated the association between genetic mutations related to iron metabolism have been inconsistent. Further, several clinical trials suggest that by phlebotomy induced reduction in body iron levels may improve insulin sensitivity in humans. However, no interventional studies have yet directly evaluated the effect of reducing iron intake or body iron levels on the risk of developing type 2 diabetes. Such studies are required to prove the causal relationship between moderate iron overload and diabetes risk. Biochimica et biophysica acta [Biochim Biophys Acta] -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > so, you can't actually rebute anything? [that is of course a rhetorical > question] [quoted text clipped - 55 lines] > > - Show quoted text - Remember those that fear it the most have something to hide. ;) CB > and you post such homophobic thoughts because? > [quoted text clipped - 63 lines] >> > >> > - Show quoted text - well tom - i read that you are still inventing quotes and thus misrepresenting what others have actually written - really a shame that you don't seem able to simply state your case without resorting to fabrication with that said, i also notice that you have - after significant prodding from others - provided folk with a 'connection' to at least one of the cross-posted groups from your original post. i would be remiss in not commenting that you have in fact posted a legitimate study, albeit an old [2003] one that many have already seen - and also that while valid as a 'connection' it in no way addresses 'causality'. as such, it is applicable in only a peripheral [pun intended] way. of course you don't seem to be aware of the earlier kuseife clinic study which showed the issue first, but what the heck, there is a whole lot you don't know for example, there is dellon's work on differentiating diabetic muscle aches vs the more generalized 'classic' fibro symtomolgy, Dellon AL, Shookster L, Maloney CT, Ducic I.: Diagnosis of compressive neuropathies in patients with fibromyalgia. or, Fibromyalgia and Tinels Sign in the Foot, by Shookster, L, Falke, G.I., Ducic, I, Maloney, C.T., and Dellon, A.L., volume 94:400-403, 2004. perhaps, if you weren't so fixated, you might have known of st. amand's study on the relationship of hypoglcenia as it relates to what the study you cited shows shucks, you might even have been able to discuss the known association between fibro, diabetes, and magnesium deficiencies, or the aberrant insulin-adrenaline reaction, as has been pointed out by others, you are, mostly, just regurgitating partially understood information, gleaned by web searching, with a singular objective in mind. as a result, you position yourself as an overbearing, johnny-one-note, who argues about what folk 'didn't' say, invents statements that don't exist, and can't even state his own thoughts without attempting to demean others and you complain about being mocked... > On Jun 10, 6:53 pm, Alan <a...@usuk.com> wrote: I guess "eat me" > means you lost this one. << [quoted text clipped - 127 lines] > > > > - Show quoted text - On Jun 11, 2:07 pm, "Paul T. Holland" <pholl...@bellatlantic.net> wrote: long winded whack << Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > well tom - i read that you are still inventing quotes and thus > misrepresenting what others have actually written - really a shame that [quoted text clipped - 174 lines] > > - Show quoted text - well gosh tommy posting further information specifically as it pertains to what you have written is now 'whack'? i point out that you have invented quotes and you aren't able to provide back up for those inventions i point out the alterations you make to sentences - you aren't able to justify it i show that your information while a legitimate study is, to be sure, a bit 'old news' and amplify on it with other studies and information showing the complexity of the issue as to causality you are being a 'one note' and again going the sneering nasty route i guess i'll just have to continue to be whack then - you can count on it. > On Jun 11, 2:07 pm, "Paul T. Holland" <pholl...@bellatlantic.net> > wrote: long winded whack << [quoted text clipped - 189 lines] > > > > - Show quoted text - well gosh and by golly - i guess a bit more logic is necessary > On Jun 10, 3:38 pm, "Paul T. Holland" <pholl...@bellatlantic.net> > wrote: snip << > > Long winded whack stroking himself .. tell everyone tom, has your repeated [in many posts to many individuals] reference to self-gratification 'ever' worked as a 'scathing' retort with anyone you 'try' to belittle it with? in a diff. post i did mention that you can't have a claim to any high road when you write such to folk - not to mention that it only makes folk laugh at your inchoate ranting > I see you finally answered the question .. logic alert: you see? really? it is really quite amazing that you would make such an 'illogical' claim since i did not, it is not logical for you to state that you can 'see' any such thing. your only 'logical' recourse is to quote the post in which you claim [guess] i did so > Fibromyalgia is the group you have figure is not related to diabetes. continuation of logic: since i, or a family member, have one of the medical conditions represented in each of the cross-posted groups this thread is going out to - and, as a result i have frequented each of them for many years both as a contributor and a lurker reading for information, the simple fact is that you have no idea which group may, or may not be, the one from which i first responded, nor do you have any knowledge of which group each succeeding reply may, or may not, be originating from it therefore continues that any 'guess' [claim] that you have discerned which group i may or may not have intended to reference is false on your part quoting you: > Fibromyalgia is the group you have figure is not related to diabetes. it is also false that i 'figure' any one [or none] is 'related' to diabetes - what is 'true' is that you don't actually know 'what' i figure. what is true is that you had been asked to state the relationship that existed in your mind to have posted a specific study concerning diabetes in each of those other groups - without which, it is not unreasonable to feel that this was, in some cases, a contravention of the charter for a/the group > Now like I already pointed .. out .. you could not figure what you pointed out tom, was an incorrect 'inference' as a result of your misapprehension of what i 'did' write - not to mention your then snippage of my 'complete' thought as expressed by the totality of the actual sentence construction as i wrote it. > **conclusively** / "may belong in diabetes" .. tom oh tom - once again you 'snip' the full sentence, and thus do not convey the total thought, but be that as it may, you are still incorrect in your conclusion since you are unable to comprehend on your own; herewith you are provided with a simple review of the words you left in, per merriam-webster dictionary, showing the meaning of the words: 'may': "have permission or liberty to" 'belong': "to be suitable or appropriate" 'in': "used to indicate physical surroundings so you 'see' tom, logically, and "> **conclusively**", there wasn't any lack of certainty, or ambiguity ,in what i wrote - only in your incorrect interpretation. >an you figure you CAN continuation of logic lesson: this is a supposition on your part - as already determined, you have no idea at all, nor any way to determine since you haven't bothered to 'simply' ask another person a reasonable question sans accusation and innuendo. > figure out whether it belongs in .. fibromyalgia .. also supposition on your part - as shown, you have no way of knowing which group [if in fact it is only one of the many] i may, or may not, have been referring to. > Like I said .. you cannot .. evidenced by .. ? the logic of what is actually written as opposed to what you have demonstrably 'inferred' > The fact you are .. again .. whining how it "doesn't belong and is not > related to diabetes" .. lololololol why tom, i neither whined, nor wrote the above - yet you are the one who complains about how your writings are received and the words 'others' use to address you. as long as you continue to just make up quotes that another didn't actually write, why should you be viewed as worthy of respect? > Sooo .. let me synopsy !lol! well, congratulations - you actually used it correctly >what you said .. was first, a query not a statement, then corrections of your false restatements of what i 'didn't' write in the first place >"diabetes is not related to > fibromyalgia" .. logic: if i never wrote it, you can't restate it as a synopsis...lololol > You are wrong .. that would only be true if what you so earnestly tried to 'synopsy' actually reflected what i 'did' question and later state. since you haven't - i am not...lol > Need proof .. ? well since i have already provided parsing and logic, no > Eat me .. but tom! since you insist everyone should be a vegetarian - i find your request to be hypocritical > Who loves ya. > Tom thanks for providing another bit of silliness tom, you're a hoot when you get like this. On Jun 11, 1:09 pm, "Paul T. Holland" <pholl...@bellatlantic.net> wrote: long winded whack .. << Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk shucks tommy - i point out that you aren't telling the truth, i even take the time to give you a vocabulary lesson concerning a specific untruth use of logic and language is now 'whack'? then 'up with whack!!!" whack every day! tommy desires MORE whack! > On Jun 11, 1:09 pm, "Paul T. Holland" <pholl...@bellatlantic.net> > wrote: long winded whack .. << [quoted text clipped - 10 lines] > DEAD PEOPLE WALKING > http://tinyurl.com/zk9fk Paul's not "whack" He's just playing Whack-a-Mole. Everytime Tommy pops his head up Paul's there to whack him. http://www.dorneypark.com/public/online_fun/mole.cfm CB > shucks tommy - i point out that you aren't telling the truth, i even > take the time to give you a vocabulary lesson concerning a specific [quoted text clipped - 22 lines] >> DEAD PEOPLE WALKING >> http://tinyurl.com/zk9fk snip << Find something to do .. The role of iron in type 2 diabetes in humans. Rajpathak SN, Crandall J, Wylie-Rosett J, Kabat GC, Rohan TE, Hu FB Biochim Biophys Acta 2008 May 3. The role of micronutrients in the etiology of type 2 diabetes is not well studied. Several lines of evidence suggest that iron may a role in the pathogenesis of type 2 diabetes. Iron is a strong pro-oxidant and high body iron levels are associated with increased level of oxidative stress that may elevate the risk of type 2 diabetes. Several epidemiological studies have reported a positive association between high body iron levels, as measured by circulating ferritin level, and the risk of type 2 diabetes and of other insulin resistance states such as the metabolic syndrome, gestational diabetes and polycystic ovarian syndrome. In addition, increased dietary intake of iron, especially that of heme iron, is associated with risk of type 2 diabetes in apparently healthy populations. Results from studies that evaluated the association between genetic mutations related to iron metabolism have been inconsistent. Further, several clinical trials suggest that by phlebotomy induced reduction in body iron levels may improve insulin sensitivity in humans. However, no interventional studies have yet directly evaluated the effect of reducing iron intake or body iron levels on the risk of developing type 2 diabetes. Such studies are required to prove the causal relationship between moderate iron overload and diabetes risk. Biochimica et biophysica acta [Biochim Biophys Acta] -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk On Jun 12, 2:43 pm, "Cheeky Bastard" <InvalidEm...@aol.com> wrote: snip << >Find something to do .. I have, I like pissing on your head when you continue to post to AMF. You like it don't you pig? <g> On Jun 12, 9:25 pm, "Cheeky Bastard" <InvalidEm...@aol.com> wrote:You like it don't you pig? << Why should I .. care .. about a retarded fatboy like .. you ..? The role of iron in type 2 diabetes in humans. Rajpathak SN, Crandall J, Wylie-Rosett J, Kabat GC, Rohan TE, Hu FB Biochim Biophys Acta 2008 May 3. The role of micronutrients in the etiology of type 2 diabetes is not well studied. Several lines of evidence suggest that iron may a role in the pathogenesis of type 2 diabetes. Iron is a strong pro-oxidant and high body iron levels are associated with increased level of oxidative stress that may elevate the risk of type 2 diabetes. Several epidemiological studies have reported a positive association between high body iron levels, as measured by circulating ferritin level, and the risk of type 2 diabetes and of other insulin resistance states such as the metabolic syndrome, gestational diabetes and polycystic ovarian syndrome. In addition, increased dietary intake of iron, especially that of heme iron, is associated with risk of type 2 diabetes in apparently healthy populations. Results from studies that evaluated the association between genetic mutations related to iron metabolism have been inconsistent. Further, several clinical trials suggest that by phlebotomy induced reduction in body iron levels may improve insulin sensitivity in humans. However, no interventional studies have yet directly evaluated the effect of reducing iron intake or body iron levels on the risk of developing type 2 diabetes. Such studies are required to prove the causal relationship between moderate iron overload and diabetes risk. Biochimica et biophysica acta [Biochim Biophys Acta] -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > On Jun 12, 2:43 pm, "Cheeky Bastard" <InvalidEm...@aol.com> wrote: > snip << [quoted text clipped - 4 lines] > > You like it don't you pig? <g> now, now, cb - t'were just the logic lesson he requested... > Paul's not "whack" He's just playing Whack-a-Mole. > [quoted text clipped - 28 lines] > >> DEAD PEOPLE WALKING > >> http://tinyurl.com/zk9fk On Jun 13, 2:56 pm, "Paul T. Holland" <pholl...@bellatlantic.net> wrote:long winded whack << The role of iron in type 2 diabetes in humans. Rajpathak SN, Crandall J, Wylie-Rosett J, Kabat GC, Rohan TE, Hu FB Biochim Biophys Acta 2008 May 3. The role of micronutrients in the etiology of type 2 diabetes is not well studied. Several lines of evidence suggest that iron may a role in the pathogenesis of type 2 diabetes. Iron is a strong pro-oxidant and high body iron levels are associated with increased level of oxidative stress that may elevate the risk of type 2 diabetes. Several epidemiological studies have reported a positive association between high body iron levels, as measured by circulating ferritin level, and the risk of type 2 diabetes and of other insulin resistance states such as the metabolic syndrome, gestational diabetes and polycystic ovarian syndrome. In addition, increased dietary intake of iron, especially that of heme iron, is associated with risk of type 2 diabetes in apparently healthy populations. Results from studies that evaluated the association between genetic mutations related to iron metabolism have been inconsistent. Further, several clinical trials suggest that by phlebotomy induced reduction in body iron levels may improve insulin sensitivity in humans. However, no interventional studies have yet directly evaluated the effect of reducing iron intake or body iron levels on the risk of developing type 2 diabetes. Such studies are required to prove the causal relationship between moderate iron overload and diabetes risk. Biochimica et biophysica acta [Biochim Biophys Acta] -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk Paul looks like he's run out of any sort of witty retorts. ;) > now, now, cb - t'were just the logic lesson he requested... > [quoted text clipped - 30 lines] >> >> DEAD PEOPLE WALKING >> >> http://tinyurl.com/zk9fk testosterone depleted retarded fatboy << The role of iron in type 2 diabetes in humans. Rajpathak SN, Crandall J, Wylie-Rosett J, Kabat GC, Rohan TE, Hu FB Biochim Biophys Acta 2008 May 3. The role of micronutrients in the etiology of type 2 diabetes is not well studied. Several lines of evidence suggest that iron may a role in the pathogenesis of type 2 diabetes. Iron is a strong pro-oxidant and high body iron levels are associated with increased level of oxidative stress that may elevate the risk of type 2 diabetes. Several epidemiological studies have reported a positive association between high body iron levels, as measured by circulating ferritin level, and the risk of type 2 diabetes and of other insulin resistance states such as the metabolic syndrome, gestational diabetes and polycystic ovarian syndrome. In addition, increased dietary intake of iron, especially that of heme iron, is associated with risk of type 2 diabetes in apparently healthy populations. Results from studies that evaluated the association between genetic mutations related to iron metabolism have been inconsistent. Further, several clinical trials suggest that by phlebotomy induced reduction in body iron levels may improve insulin sensitivity in humans. However, no interventional studies have yet directly evaluated the effect of reducing iron intake or body iron levels on the risk of developing type 2 diabetes. Such studies are required to prove the causal relationship between moderate iron overload and diabetes risk. Biochimica et biophysica acta [Biochim Biophys Acta] -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk lol cb - i was being 'iron'ic > Paul looks like he's run out of any sort of witty retorts. ;) > [quoted text clipped - 32 lines] > >> >> DEAD PEOPLE WALKING > >> >> http://tinyurl.com/zk9fk Ooops my typo, I left out a word. Should have read. Paul it looks like he's run out of any sort of witty retorts. I meant rusty. Sorry Bud CB > lol cb - i was being 'iron'ic > [quoted text clipped - 34 lines] >> >> >> DEAD PEOPLE WALKING >> >> >> http://tinyurl.com/zk9fk testosterone depleted retarded fatboy << The role of iron in type 2 diabetes in humans. Rajpathak SN, Crandall J, Wylie-Rosett J, Kabat GC, Rohan TE, Hu FB Biochim Biophys Acta 2008 May 3. The role of micronutrients in the etiology of type 2 diabetes is not well studied. Several lines of evidence suggest that iron may a role in the pathogenesis of type 2 diabetes. Iron is a strong pro-oxidant and high body iron levels are associated with increased level of oxidative stress that may elevate the risk of type 2 diabetes. Several epidemiological studies have reported a positive association between high body iron levels, as measured by circulating ferritin level, and the risk of type 2 diabetes and of other insulin resistance states such as the metabolic syndrome, gestational diabetes and polycystic ovarian syndrome. In addition, increased dietary intake of iron, especially that of heme iron, is associated with risk of type 2 diabetes in apparently healthy populations. Results from studies that evaluated the association between genetic mutations related to iron metabolism have been inconsistent. Further, several clinical trials suggest that by phlebotomy induced reduction in body iron levels may improve insulin sensitivity in humans. However, no interventional studies have yet directly evaluated the effect of reducing iron intake or body iron levels on the risk of developing type 2 diabetes. Such studies are required to prove the causal relationship between moderate iron overload and diabetes risk. Biochimica et biophysica acta [Biochim Biophys Acta] -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk in my best senor winchez's voice from the box: 'sawright' > Ooops my typo, I left out a word. Should have read. Paul it looks like he's > run out of any sort of witty retorts. [quoted text clipped - 42 lines] > >> >> >> DEAD PEOPLE WALKING > >> >> >> http://tinyurl.com/zk9fk On Jun 15, 5:16 pm, "Paul T. Holland" <pholl...@bellatlantic.net> wrote: long winded whack << The role of iron in type 2 diabetes in humans. Rajpathak SN, Crandall J, Wylie-Rosett J, Kabat GC, Rohan TE, Hu FB Biochim Biophys Acta 2008 May 3. The role of micronutrients in the etiology of type 2 diabetes is not well studied. Several lines of evidence suggest that iron may a role in the pathogenesis of type 2 diabetes. Iron is a strong pro-oxidant and high body iron levels are associated with increased level of oxidative stress that may elevate the risk of type 2 diabetes. Several epidemiological studies have reported a positive association between high body iron levels, as measured by circulating ferritin level, and the risk of type 2 diabetes and of other insulin resistance states such as the metabolic syndrome, gestational diabetes and polycystic ovarian syndrome. In addition, increased dietary intake of iron, especially that of heme iron, is associated with risk of type 2 diabetes in apparently healthy populations. Results from studies that evaluated the association between genetic mutations related to iron metabolism have been inconsistent. Further, several clinical trials suggest that by phlebotomy induced reduction in body iron levels may improve insulin sensitivity in humans. However, no interventional studies have yet directly evaluated the effect of reducing iron intake or body iron levels on the risk of developing type 2 diabetes. Such studies are required to prove the causal relationship between moderate iron overload and diabetes risk. Biochimica et biophysica acta [Biochim Biophys Acta] -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk On Jun 9, 7:53 am, "ironjust...@aol.com" <ironjust...@aol.com> wrote: Role of iron in type 2 diabetes << "Phlebotomy Successfully Treats Cardiomyopathy" -------------------------------------- "Tissue stains from a heart biopsy showed an extremely high level of iron which was the cause of his cardiomyopathy that led to congestive heart failure. Diagnosis was hereditary hemochromatosis leading to diabetes and cardiomyopathy." http://tinyurl.com/3zh3et -------------------------------------- "Phlebotomy Successfully Treats Cardiomyopathy" Internist (Berl). 2008 Jan 23 [Epub ahead of print] Links [28-year old patient with successfully treated dilatative cardiomyopathy.][Article in German] Burri E, Decker M, Eriksson U, Buser P, Hunziker L. Innere Medizin, Universitätsspital Basel, Petersgraben 4, 4031, Basel, Schweiz, Bur...@uhbs.ch. A 28-year was admitted with heart failure. His medical history included treatment for hypogonadotropic hypogonadism. Echocardiography showed dilatation of all chambers. Elevated serum ferritin levels and liver biopsy indicated hereditary hemochromatosis. Cardiac iron overload was seen on magnetic resonance imaging. Genetic testing revealed homozygosis for G320 V mutation, confirming the diagnosis of juvenile hemochromatosis. Phlebotomy on a biweekly regimen was started and after twelve months of therapy the patient had normal ferritin values as well as normal ejection fraction on echocardiography. PMID: 18210019 [PubMed - as supplied by publisher] Who loves ya. Tom Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk > The role of iron in type 2 diabetes in humans. > Rajpathak SN, Crandall J, Wylie-Rosett J, Kabat GC, Rohan TE, Hu FB [quoted text clipped - 36 lines] > > DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk > On Jun 9, 7:53 am, "ironjust...@aol.com" <ironjust...@aol.com> wrote: > Role of iron in type 2 diabetes << > > "Phlebotomy Successfully Treats Cardiomyopathy" Didn't Dr. Dracula do the first research on that. He had to stop early, as he sucked all the research funds dry trying to clean up the bloody mess |
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