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Medical Forum / Diseases and Disorders / Lupus / February 2008

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Standin For Incapacitating Pain

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ironjustice@aol.com - 12 Feb 2008 15:20 GMT
"Necessitating the use of analgesics"

Sooo .. THEY cause the .. **need** FOR pain relievers.
Kinda .. convenient ..
Sorta like my ripoff snfabtch mechanic ..
Excuse me ..

DGNews
FDA Provides Updated Information on Bisphosphonates
ROCKVILLE, MD -- January 7, 2008 -- FDA is highlighting the
possibility of severe and sometimes incapacitating bone, joint, and/or
muscle (musculoskeletal) pain in patients taking bisphosphonates
(marketed as Actonel, Actonel+Ca, Aredia, Boniva, Didronel, Fosamax,
Fosamax+D, Reclast, Skelid, and Zometa). Although severe
musculoskeletal pain is included in the prescribing information for
all bisphosphonates, the association between bisphosphonates and
severe musculoskeletal pain may be overlooked by healthcare
professionals, delaying diagnosis, prolonging pain and/or impairment,
and necessitating the use of analgesics.

The severe musculoskeletal pain may occur within days, months, or
years after starting a bisphosphonate. Some patients have reported
complete relief of symptoms after discontinuing the bisphosphonate,
whereas others have reported slow or incomplete resolution. The risk
factors for and incidence of severe musculoskeletal pain associated
with bisphosphonates are unknown.

This severe musculoskeletal pain is in contrast to the acute phase
response characterized by fever, chills, bone pain, myalgias, and
arthralgias that sometimes accompanies initial administration of
intravenous bisphosphonates and may occur with initial exposure to
once-weekly or once-monthly doses of oral bisphosphonates. The
symptoms related to the acute phase response tend to resolve within
several days with continued drug use.

Healthcare professionals should consider whether bisphosphonate use
might be responsible for severe musculoskeletal pain in patients who
present with these symptoms and consider temporary or permanent
discontinuation of the drug.

SOURCE: U.S. Food and Drug Administration

-------------------------------------------------------------------------------
Bisphosphonate For Free / Free Bisphosphonate

http://tinyurl.com/yrnxy7

http://www.news-medical.net/?id=11842

"There is no evidence currently available to definitely confirm that
one bisphosphonate is better than another, mainly because the
appropriate studies have not been done," he adds.

I would say .. there IS evidence .. one is better than the other ..
mine costs .. nothing.

It is .. free.

-----------------------------------------------

You know there seems to be a bisphosphonate found in your .. grub .. a
'standin' .. ?

Phytate / phytic acid .. found in the chaff of your grain and in your
plants compared to .. etidronate.

http://tinyurl.com/2wuhuk

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com

Man Is A Herbivore!
http://tinyurl.com/a3cc3

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
John Husvar - 13 Feb 2008 12:52 GMT
In article
<13a10940-18aa-4440-852c-21ed5ec2512e@v4g2000hsf.googlegroups.com>,

> Sorta like my ripoff snfabtch mechanic ..
> Excuse me ..

Tom, lad, you misspelled sumbitch. :)
wrthomps@ix.netcom.com - 13 Feb 2008 13:45 GMT
Rusty <halfbaked@myBQQ> rambled:

<snip>

Okay, Rusty, you're obviously perfect for the job, but
*why* do you want to stand in for incapacitating pain?

--Bill Thompson
 
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