I suppose this might explain **why** .. bloodletting... works.

Bloodletting / phlebotomy / venesection .. lowers .. iron.

Ferritin .. is .. iron .. http://tinyurl.com/2eu48a

Titre du document / Document title
Serum ferritin as a serologic marker of activity in systemic lupus
erythematosus
Auteur(s) / Author(s)
LIM M.-K. (1) ; LEE C.-K. (1 2) ; JU Y. S. (1) ; CHO Y. S. (1) ; LEE
M.-S. (1 2) ; YOO B. (1) ; MOON H.-B. (1) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Department of Internal Medicine, Asan Medical Center, University
of Ulsan College of Medicine, 388-1 Poognap-dong Songpa-gu, Seoul
138-736, COREE, REPUBLIQUE DE
(2) Department of Preventive Medicine, Asan Medical Center, University
of Ulsan College of Medicine, Seoul, COREE, REPUBLIQUE DE

Résumé / Abstract
To investigate the relationship between serum ferritin and disease
activity in systemic lupus erythematosus (SLE), we enrolled 128
patients with SLE (18 males and 110 females). Twenty-eight patients (2
males and 26 females) with rheumatoid arthritis (RA) served as
controls. The SLE patients were subdivided into three groups according
to Systemic Lupus Erythematosus Disease Activity Index (SLEDAI)
scores: groups A (0-5), B (6--9), and C (≥10). We prospectively
evaluated 48 SLE patients before and after treatment. Serum ferritin
and anti-dsDNA antibody were measured by radioimmunometric assay. C-
reactive protein (CRP) was measured quantitatively by
immunonephelometry. Complements 3 and 4 (C3 and C4) were measured by
nephelometry. Serum levels of ferritin during the more active stage of
SLE (group C) exceeded those of RA patients and patients at less
active stages of SLE (groups A and B). There were no significant
differences between RA patients and groups A and B. Serum ferritin was
elevated especially in serositis and hematologic manifestation. In
this prospective study, changes in SLEDAI scores before and after
treatment correlated significantly with serum ferritin levels and
inversely to C3 and C4 levels. We confirm that serum ferritin levels
can be a useful marker of disease activity in SLE patients.
Revue / Journal Title
Rheumatology international  (Rheumatol. int.)  ISSN 0172-8172
Source / Source
2001, vol. 20, no3, pp. 89-93 (26 ref.)
Langue / Language
Anglais

Editeur / Publisher
Springer, Berlin, ALLEMAGNE (1981) (Revue)

Mots-clés anglais / English Keywords
Lupus erythematosus ; Disseminated ; Biochemical analysis ; Ferritin ;
Serum ; Concentration ; Correlation analysis ; Evolutivity ;
Symptomatology ; Human ; Skin disease ; Connective tissue disease ;
Systemic disease ; Autoimmune disease ; Immunopathology ;
Mots-clés français / French Keywords
Lupus érythémateux ; Disséminé ; Analyse biochimique ; Ferritine ;
Sérum ; Concentration ; Analyse corrélation ; Evolutivité ;
Symptomatologie ; Homme ; Peau pathologie ; Tissu conjonctif
pathologie ; Maladie système ; Maladie autoimmune ;
Immunopathologie ;

002b07 ;
Mots-clés espagnols / Spanish Keywords
Lupus eritematoso ; Diseminado ; Análisis bioquímico ; Ferritina ;
Suero ; Concentración ; Análisis correlación ; Evolutividad ;
Sintomatología ; Hombre ; Piel patología ; Tejido conjuntivo
patología ; Enfermedad sistémica ; Enfermedad autoinmune ;
Inmunopatología ;
Localisation / Location
INIST-CNRS, Cote INIST : 18212, 35400009507683.0020

Copyright 2006 INIST-CNRS. All rights reserved

Toute reproduction ou diffusion même partielle, par quelque procédé ou
sur tout support que ce soit, ne pourra être faite sans l'accord
préalable écrit de l'INIST-CNRS.
No part of these records may be reproduced of distributed, in any form
or by any means, without the prior written permission of INIST-CNRS.

Nº notice refdoc (ud4) : 954051

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Rosacea associated with polycythemia vera: Skin lesions improved with
phlebotomy
---------------------------------------------------------------------------­­-----
Suhr, Ki-Beom; Yoon, Ji-Seong; Lee, Jeung-Hoon; Park, Jang-Kyu 1994
Annals of Dermatology 6(1): 98-101

We report a case of rosacea in a 65 year old female with a 14 year
history of polycythemia vera. The patient suffered from several
constitutional symptoms and signs suggestive of polycythemia vera.
Six
years prior to our initial examination, erythematous lesions were
first noted on the center of the face. These lesions exhibited
periodic improvement and exacerbation without specific treatment.
Histopathologic examination of the facial lesions showed nodular
infiltration of lymphocytes and histiocytes and dilation of blood
vessels. On the basis of laboratory examination, the patient was
diagnosed as polycythemia vera. The patient has received
metronidazole, tetracycline, and topical steroids to control rosacea-
like facial lesions. The treatment results were not significant.
However, phlebotomy markedly improved the skin lesion. To our
knowledge, there are no reports describing the clinical course of
rosacea lesions following the treatment with phlebotomy.

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com

Man Is A Herbivore!
http://tinyurl.com/a3cc3

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk