Rosacea associated with polycythemia vera: Skin lesions improved with
phlebotomy
--------------------------------------------------------------------------------
Suhr, Ki-Beom; Yoon, Ji-Seong; Lee, Jeung-Hoon; Park, Jang-Kyu 1994
Annals of Dermatology 6(1): 98-101

We report a case of rosacea in a 65 year old female with a 14 year
history of polycythemia vera. The patient suffered from several
constitutional symptoms and signs suggestive of polycythemia vera. Six
years prior to our initial examination, erythematous lesions were
first noted on the center of the face. These lesions exhibited
periodic improvement and exacerbation without specific treatment.
Histopathologic examination of the facial lesions showed nodular
infiltration of lymphocytes and histiocytes and dilation of blood
vessels. On the basis of laboratory examination, the patient was
diagnosed as polycythemia vera. The patient has received
metronidazole, tetracycline, and topical steroids to control rosacea-
like facial lesions. The treatment results were not significant.
However, phlebotomy markedly improved the skin lesion. To our
knowledge, there are no reports describing the clinical course of
rosacea lesions following the treatment with phlebotomy.

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