 |
 | Home | Contact Us | FAQ | Search & Site Map | Link to Us |
 | Sign In | Join | Other 45 Sites in Network |
Medical Forum / Diseases and Disorders / Lupus / September 2006Joint complaints and blistering skin lesions on sun-exposed skin
Neth J Med. 2006 Sep;64(8):307-9. Links Sporadic porphyria cutanea tarda due to haemochromatosis.de Geus HR, Dees A. Department of Intensive Care, Erasmus Medical Centre, Rotterdam, the Netherlands. Haemochromatosis is a hereditary iron-overload syndrome caused by increased intestinal iron absorption and characterised by accumulation of potentially toxic iron in the tissues. Sometimes this disease presents as a cutanea porphyria. We describe a patient with joint complaints and blistering skin lesions on sun-exposed skin. After identifying the porphyria cutanea tarda by urine analysis we found that the serum activity of uroporphyrinogen decarboxylase (UROD) was normal, meaning a partial inactivation of UROD in liver tissue due to external factors. Further investigation showed the homozygous Cys282Tyr missense mutation and high levels of serum ferritin. It is important to recognise the symptoms of iron overloading at an early stage because hereditary haemochromatosis needs to be treated immediately. We therefore advocate routine sampling of ferritin levels in patients with unexplained joint complaints. PMID: 16990695 [PubMed - in process] Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk I am interested in this report as I have been looking for something for my wife. she had chemo 6 years ago and 3 years ago, developed extreme sensivity to the sun. No known cause or solution at this stage. I am sure it is a toxin, but blood tests show normal blood levels of most common metals etc. Any ideas?? thanks > Neth J Med. 2006 Sep;64(8):307-9. Links > Sporadic porphyria cutanea tarda due to haemochromatosis.de Geus HR, [quoted text clipped - 30 lines] > DEAD PEOPLE WALKING > http://tinyurl.com/zk9fk > I am interested in this report as I have been looking for something for > my wife. she had chemo 6 years ago and 3 years ago, developed extreme [quoted text clipped - 38 lines] > > DEAD PEOPLE WALKING > > http://tinyurl.com/zk9fk >>developed extreme sensivity to the sun.<< It depends I suppose on what kind of .. "sensitivity to the sun" .. you are talking about .. but not .. really .. Radiation leads to a decrease of antioxidants in the body .. Radiation is just oxidation .. Soooo .. I would increase my intake of antioxidant rich foods .. and decrease my intake of foods which .. decrease .. antioxidants. Uveitis / sensitivity to the sun in your .. eyes .. has been shown to be linked to a decrease in antioxidants .. ie: "oxidant thrust " .. http://tinyurl.com/qh8aq Same with sensitivity to the sun .. hence the addition of antioxidants to topical preparations for the skin to prevent sunburn .. http://tinyurl.com/s2gx9 >>Any ideas??<< It seems the "phosphate groups" mentioned in this study are simply the ingredients found in vegetable oil / lecithin and therefore .. in theory .. vegetable oil rich in phosphate groups applied liberally to the skin should lead to decreased oxidation and increased antioxidants IN the body / your wife. http://tinyurl.com/hr6kh Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk |
Reply to this Message |
 Sign In
 Join
 My Latest Posts My Monitored Threads My Blog My Photo Gallery My Profile My Homepage Start New Thread Enable EMail Alerts Rate this Thread
|
©2009 Advenet LLC Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.