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Medical Forum / Diseases and Disorders / Lupus / July 2005

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Sunblock from Canada?

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janers - 20 Jul 2005 16:11 GMT
In the news there seems to be a big thing with people going across the
border, into Canada at Windsor. They are buying the sunblock that is
illegal in the USA. But very effective Sunblock.   The two they are talking
about is L'Oreal products, Ombrelle and the expensive one Anthelios.

These two products contain Mexoryl which protects the skin from
ultraviolet-A rays that penetrate Deep into the skin and cause wrinkles
too.  Apparantly you can buy these products cheaper at Ebay.  3

FDA spokes person says she wasn't allowed to comment when the products
would be availble in the US.  The Canadian government says it will consider
new restrictions on selling prescription drugs to the Americans.  Nice huh?

If the US don't get off their soapbox and get the meds we need at a better
price, I say go where you can.  After all some of the medications we do get
are already from Canada.
How stupid do they think we are?/

me who else
KCat - 20 Jul 2005 17:54 GMT
> These two products contain Mexoryl which protects the skin from
> ultraviolet-A rays that penetrate Deep into the skin and cause wrinkles
> too.  Apparantly you can buy these products cheaper at Ebay.  3

<snippage>

> If the US don't get off their soapbox and get the meds we need at a better
> price, I say go where you can.  After all some of the medications we do get
> are already from Canada.
> How stupid do they think we are?/
>
> me who else

Hi Janers... I just mentoined this product briefly in the above thread to
Worried Hubby.  There was a good article about it in... uh.. some paper.
grr.. dont' remember.  anyway - I think this is silly.  This product has
been in use for a number of years and has a good record of safety.

I can't help but wonder if there are some interest groups out there who are
not wanting to cut into their titanium dioxide or zinc oxide profits?  I'm
not typically a conspiracy theorist but this is not a dangerous drug and in
fact could be saving lives.  Very frustrating.  If I could find it around
here, I would buy it.

of course, that theory doesn't make a lot of sense because the meroxyl is
only one ingredient in these products that also tend to have other UV
blockers.  It's the combination that makes it more effective overall than
what is currently legally available in the US.

rant over

me too. :)
William R  Thompson - 20 Jul 2005 19:46 GMT
> Hi Janers... I just mentioned this product briefly in the above thread to
> Worried Hubby.  There was a good article about it in... uh.. some paper.
> grr.. dont' remember.  anyway - I think this is silly.  This product has
> been in use for a number of years and has a good record of safety.

> I can't help but wonder if there are some interest groups out there who
> are
[quoted text clipped - 3 lines]
> fact could be saving lives.  Very frustrating.  If I could find it around
> here, I would buy it.

Same here, now that I know about it.  After googling mexoryl I can
only find that the FDA won't comment on their approval process.
It may be that they're waiting for all their test results--even with
something as short-lived as lab mice it takes time for dangerous
side-effects to show up.  If they give premature approval, and it
turns out they guessed wrong, they're in trouble.

My search turned up this snippet from a June 2004 article:

"While on trips to Canada or Europe, sun-savvy consumers stock up on
Mexoryl-carrying products like Anthélios (from La Roche-Posay) and
Ombrelle. Oddly, both can also be found at the New York apothecaries
Zitomer (888-219-2888) and C. O. Bigelow (800-793-5433) and online
at skincarelab.com, feelbest.com and candrugstore.com."

--Bill Thompson
KCat - 21 Jul 2005 17:51 GMT
> Same here, now that I know about it.  After googling mexoryl I can
> only find that the FDA won't comment on their approval process.
> It may be that they're waiting for all their test results--even with
> something as short-lived as lab mice it takes time for dangerous
> side-effects to show up.  If they give premature approval, and it
> turns out they guessed wrong, they're in trouble.

yes.... but that's not stopped them with drugs that pharmacies can make lots
of money on.  Can we say "Vioxx"?  And many other fast-track drugs.  One of
the problems with this is that it will not be prescription and therefore not
something they can control in the same way or that Big Pharma as it is now
called by some can make money off of.

I sound like one of those paranoid nuts i suppose but lately I've been
disgusted with how the FDA handles some of these things.  OTOH, I'm equally
disgusted with the fact that the media puts out warnings about drugs that
have dangers, yet also have very important uses that can outweigh their
risks.  For that reason, while I am not allowed to and probably never would
take Vioxx, I am not condemning Merck or anyone else for marketing the drug.
I just think that fast-tracking is used so selectively as to be of very
little use to the average person and a risk to those who might really need
and use the drug.

One of the problems here that most irritates me is the fact that overseas
data is ignored.  I heard a very astute(?) woman say that she would
"consider the possibility of legalizing marijuana for medical use when she
can see peer-reviewed studies showing it's medicinal value."  Well, the
problem with this is that of course - here in the US, it is nigh impossible
to legally study the drug.  Very few US pharmaceutical companies are a)
going to go through the hassle of getting approval for such a study or
b)skip that step and risk prosecution.  BUT!  studies done in other
countries are not considered acceptable no matter how well-done.  So she's
asking for something she won't ever get - i suspect she knows that but it
makes her sound reasonable to say it the way she said it.

don't get me wrong, I don't want the drug, but I think it has promise for
certain conditions and it is of no more risk than any other drug on the
market.  Oxycodone is a far more dangerous drug, IMO.  But in rampant use.
And don't *even* get me started on alcohol!

It isn't the use of drugs themselves that make me upset, it's the rampant
hypocrisy.

> My search turned up this snippet from a June 2004 article:
>
[quoted text clipped - 3 lines]
> Zitomer (888-219-2888) and C. O. Bigelow (800-793-5433) and online
> at skincarelab.com, feelbest.com and candrugstore.com."

thanks, Bill.  I knew I'd heard of the NY sources.  But being in TX that is
kinda out of the realm of possibility for me.  I am curious though, is it a
federal offense to ship/sell these things?  Or just illegal to make them in
the US?  What I saw on t.v. showed that the apothecaries had them "behind
the counter"  - hey, these are skin cremes, not skin mags!  :P

yeah - some of my more liberal side is showing... sorry. normally i'm firmly
in the middle of politics but when things impact my health... i swing wayyyy
left. :)
William R  Thompson - 22 Jul 2005 10:08 GMT
> "William R Thompson" <wrthomps@ix.netcom.com> wrote :

>> Same here, now that I know about it.  After googling mexoryl I can
>> only find that the FDA won't comment on their approval process.
>> It may be that they're waiting for all their test results--even with
>> something as short-lived as lab mice it takes time for dangerous
>> side-effects to show up.  If they give premature approval, and it
>> turns out they guessed wrong, they're in trouble.

> yes.... but that's not stopped them with drugs that pharmacies can make
> lots
> of money on.  Can we say "Vioxx"?

Or "Viagra"?  ("If you use it, you'll go blind!"--"Can I use it until I need
glasses?")  Somehow I don't think Viagra will be pulled anytime soon.

I know what you mean about the foot-dragging and hypocrisy.
I get the feeling that a lot of these decisions are made for us by people
who say "I've never been sick a day in my life."  I wish they could
have a limited approval for some drugs, instead of having to act like
everything is a potential thalidomide disaster.

>> My search turned up this snippet from a June 2004 article:

>> "While on trips to Canada or Europe, sun-savvy consumers stock up on
>> Mexoryl-carrying products like Anthélios (from La Roche-Posay) and
>> Ombrelle. Oddly, both can also be found at the New York apothecaries
>> Zitomer (888-219-2888) and C. O. Bigelow (800-793-5433) and online
>> at skincarelab.com, feelbest.com and candrugstore.com."

> thanks, Bill.  I knew I'd heard of the NY sources.  But being in TX that
> is
[quoted text clipped - 4 lines]
> the US?  What I saw on t.v. showed that the apothecaries had them "behind
> the counter"  - hey, these are skin cremes, not skin mags!  :P

I just looked at the feelbest.com site.  The bad news is, they are out of
the forbidden material until October.  The good news is, this is because
they
shipped so much of it to the States; they've been swamped every since the
NY Times ran an article on it.  They say that the products pass through
US Customs without any problem.  I'm not going to contact Customs and
ask if this is legit--if mexoryl has slipped through the cracks, why upset
them?

Zitomer will let you order online at http://www.zitomer.com
CO Bigelow may have a web site, but I can't find it.  Whether or not
they have mexoryl in stock is debatable.

> yeah - some of my more liberal side is showing...

Don't worry, both of my sides are left.  Makes it hard to buy
pairs of shoes and gloves.

--Bill Thompson
J - 22 Jul 2005 18:49 GMT
William R Thompson wrote:

> "While on trips to Canada or Europe, sun-savvy consumers stock up on
> Mexoryl-carrying products like Anthélios (from La Roche-Posay) and
> Ombrelle. Oddly, both can also be found at the New York apothecaries
> Zitomer (888-219-2888) and C. O. Bigelow (800-793-5433) and online
> at skincarelab.com, feelbest.com and candrugstore.com."

Well, Im pretty sure I saw that Loreal products contain it.
I cannot find a Canadian (Health Canada) reference to Mexoryl  (usually a health
Canada website comes up right away), which makes me wonder if it's made in other
countries (Europe) and imported here??

And this Candian dermatologist says it's all hype.
<http://www.canada.com/calgary/globaltv/healthbeat/story.html?id=69e53ff5-739e-4b
3a-b35f-e2db80d172b5
>

"You will pay more for a sunscreen that contains Mexoryl, but any sunscreen that
says  broad spectrum coverage is adequate.

The other thing about it is that it's photo-stable. Some sunscreens are not
photo-stable. They contain something called Parsol 1789 which starts to break
down as soon as it's exposed to the sun versus Mexoryl SX which is photo-stable.
It's the best, but is a sunscreen that doesn't have it just as good, you bet,"
says Calgary dermatologist Dr. Greg Storwick."

However:
He's talking to the general population: I don't know if his advice would be
different to a Lupus patient.
The other thing is if it makes the product photo-stable, one doesn't have to
reapply as frequently?
Woudl that be reight?
If so, and if it's more expensive, might make it worth the extra.
J
William R  Thompson - 22 Jul 2005 20:27 GMT
> William R Thompson wrote:

>> "While on trips to Canada or Europe, sun-savvy consumers stock up on
>> Mexoryl-carrying products like Anthélios (from La Roche-Posay) and
>> Ombrelle. Oddly, both can also be found at the New York apothecaries
>> Zitomer (888-219-2888) and C. O. Bigelow (800-793-5433) and online
>> at skincarelab.com, feelbest.com and candrugstore.com."

> Well, Im pretty sure I saw that Loreal products contain it.
> I cannot find a Canadian (Health Canada) reference to Mexoryl  (usually a
> health
> Canada website comes up right away), which makes me wonder if it's made in
> other
> countries (Europe) and imported here??

I don't know yet.  Here's an Aussie site

http://www.nicnas.gov.au/PUBLICATIONS/CAR/NEW/NA/NASUMMR/NA0300SR/na399.asp

which has a brief summary of its physical properties; the bottom of this
site has a link to a PDF file which gives Mexoryl's chemical names at the
top.  Its alternate trade name is Ecamsule.  The bad news for some
people is that may include a benzene-based compound in it.  At
least the PDF page has a diagram of the molecule, and that's definitely
a benzene ring in the middle of the pretty picture.

Can someone look at the "Assessment of Toxicological Data" on the
link I gave?  It looks like Mexoryl might cause some thyroid problems
if it's used over a prolonged period (this report is ambiguous here--
the researchers found that their first group of control animals had
low thyroid weights.  These rats didn't take mexoryl, but the test
animals appear to have had some changes in thyroid weight, as
well as other things that sound less than good.)

> And this Candian dermatologist says it's all hype.
> <http://www.canada.com/calgary/globaltv/healthbeat/story.html?id=69e53ff5-739e-4b
3a-b35f-e2db80d172b5
>

> "You will pay more for a sunscreen that contains Mexoryl, but any
> sunscreen that
> says  broad spectrum coverage is adequate.

"Adequate?"  I prefer "obsessed overachiever" in my sunblocks.

> The other thing about it is that it's photo-stable. Some sunscreens are
> not
[quoted text clipped - 5 lines]
> bet,"
> says Calgary dermatologist Dr. Greg Storwick."

> However:
> He's talking to the general population: I don't know if his advice would
[quoted text clipped - 4 lines]
> reapply as frequently?
> Would that be right?

It should last longer under UV light, with fewer side effects than Parsol
1789,
which evidently breaks down into benzene-based compounds.  If nothing
else, Mexoryl appears to have fewer break-down by-products.  But it
would probably wash off/sweat off as readily as the next sunscreen.

> If so, and if it's more expensive, might make it worth the extra.

If it gives increased UV-A protection, I'd say so.  (I went to see
"War of the Worlds" the other night.  The theater has quartz-halogen
lights in its parking lot, and I had to spend a bit more time under them
than I would have liked.  At least the fatigue, chills and hand-numbness
were mild, and have passed . . . but I expected death rays in the movie,
not outside the theater . . . )

--Bill Thompson
KCat - 23 Jul 2005 03:10 GMT
> William R Thompson wrote:
> And this Candian dermatologist says it's all hype.

<http://www.canada.com/calgary/globaltv/healthbeat/story.html?id=69e53ff5-73
9e-4b3a-b35f-e2db80d172b5>

> "You will pay more for a sunscreen that contains Mexoryl, but any sunscreen that
> says  broad spectrum coverage is adequate.

I'd have to do more reading but i'm not sure I agree.  see below comments.

Part of the problem is the whole SPF system which only references UVB
blockage.  SPF on the bottle does not tell you how much UVA protection a
product has.  Only UVB.  They can call it full-spectrum when it may only
block a small percentage of UVA & UVC.

Again, see more below.

> However:
> He's talking to the general population: I don't know if his advice would be
> different to a Lupus patient.

Here is the part that makes the difference for me:
"Mexoryl SX is a molecule, invented in Europe, that has been proven to cover
the whole spectrum of UVA rays. Other sunscreens only cover part of the UVA
spectrum"

Lupus patients, as you might suspect in your question above, are thought to
react more to UVA in terms of our actual photosensitivity symptoms.
Therefore, a better blocker of UVA is of value to us, IMO, even more so than
to the average individual who is more concerned about wrinkles and looking
older.

> The other thing is if it makes the product photo-stable, one doesn't have to
> reapply as frequently?

presumably.  not sure.  also depends on how stable it is WRT sweat and
water.  Contary to the labels, Waterproof sunblocks are not.  not really.
They only have to be "waterproof" for a certain period of time to qualify
for that label.

> Woudl that be reight?
> If so, and if it's more expensive, might make it worth the extra.
> J

*I* would like it to be available.  BTB, it's the UVA from fluorescents that
make us sick.  A sunblock that better protects me from *that* would be well
worth it to me. If indeed it works.
Sherry - 25 Jul 2005 19:25 GMT
Kat, is the product available in Mexico?  If so do you know anyone who makes
trips across the border?  I used to get some of my meds yrs ago from across
the border as they were affordable there and not here.

Hugs,
sherry

>> William R Thompson wrote:
>> And this Candian dermatologist says it's all hype.
[quoted text clipped - 53 lines]
> well
> worth it to me. If indeed it works.
William R  Thompson - 25 Jul 2005 13:01 GMT
"William R Thompson" <wrthomps@ix.netcom.com> wrote:

>> Hi Janers... I just mentioned this product briefly in the above thread to
>> Worried Hubby.  There was a good article about it in... uh.. some paper.
>> grr.. dont' remember.  anyway - I think this is silly.  This product has
>> been in use for a number of years and has a good record of safety.

Found it!:

http://www.washingtonpost.com/wp-dyn/content/article/2005/06/27/AR2005062701099_
pf.html


According to the article, the main reason for the FDA foot-dragging
is that the FDA regards mexoryl as a drug.  In Europe, it (and
other sunblockers) is classified as a cosmetic, which subjects it
to less-rigorous standards.

--Bill Thompson
 
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