Hi Ben and Jamie,
I didnt use Plaquenil when I was pregnant with my son, but that was 18 years
ago!  Anyhoo...Im sure you have done internet searches yourself, but I have
access to some medical sites for professionals....here is what I found.  #4
is a study done on pregnancy and plaquenil. (I cut a pasted from the
web...hope it shows up)

1) Pregnancy-Unless you are taking it for malaria or liver disease caused by
protozoa ,

use of this medicine is not recommended during pregnancy. In animal studies,
hydroxychloroquine

has been shown to cause damage to the central nervous system (brain and
spinal cord) of the fetus,

including damage to hearing and sense of balance, bleeding inside the eyes,
and other eye problems.

However, when given in low doses (once a week) to prevent malaria, this
medicine has not been shown

to cause birth defects or other problems in pregnant women.

     2) Safety of hydroxychloroquine in pregnant patients
     November 2003. In this French study of 133 pregnant women with Lupus
who were taking hydroxychloroquine (HCQ). The study found no statistically
significant differences between the women taking HCQ and a control group.
The authors conclude,

3) Plaquenil (hydroxychloroquine) in PregnancyResearchers from Paris, France
studied 101 female patients with lupus who were taking hydroxychloroquine

(Plaquenil) during pregnancy and for at least 6 months prior to pregnancy.
They found no increase in birth defects

compared with the general population and had no visual or hearing side
effects of the drug in these patients.Dr. Shiel's Perspective: When I first
began rheumatology practice, now two decades ago, the standard of care

was to discontinue hydroxychloroquine (Plaquenil) at least 3 months prior to
pregnancy in women with lupus.

Now more and more research studies are showing that hydroxychloroquine
(Plaquenil) is not only effective

in keeping lupus quiet, but it is also relatively safe throughout pregnancy.

4)
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1
4613284&dopt=Abstract

Hope some of this helps.....take it to your doc and see what he thinks....

Janet R

[

http://www.northeastlupus.org.uk/faqshets/faqs13.htm says

Drugs and pregnancy

Drugs which are contraindicated in pregnancy include warfarin, which can
affect the foetus in the early development stage, cyclophosphamide and
methotrexate. Low dose antimalarials (plaquenil 200mg daily for example)
appear to be safe in pregnancy and can continue to be used by those
patients already on this drug. It may come as a surprise to some that
the safest medicine of all in pregnancy is steroid (a 'hormone') and
flares during pregnancy are routinely treated by changing the steroid
dosage.

This will have been written by Dr Graham Hughes, so will be based on
proper studies etc. I haven't a reference - try Googling for Hughes AND
plaquenil AND preg*

<snip>"It is always unwise to take unnecessary medications during
pregnancy. However, necessary medications should not be
discontinued. Most medications commonly taken by SLE patients are
safe to use during pregnancy. Prednisone, Prednisolone, and
probably methylprednisolone (Medrol) do not get through the
placenta and are safe for the baby. Specifically, dexamethasone
(Decadrol, Hexadrol) and betamethasone (Celestone) do reach the
baby and are used ONLY when it is necessary to treat the baby as
well. For example, these medications might be used to help the
baby's lungs mature more rapidly if the baby will be premature.
Aspirin is safe; it is often used to protect against a
complication known as toxemia of pregnancy. Preliminary reports
suggest that azathioprine (Imuran) and hydroxychloroquine
(Plaquenil) do not harm babies, but the final word is not yet in
on these. Cyclophosphamide (Cytoxan) is definitely harmful if
taken during the first three months of pregnancy. "</snip>
Info above found at this site:
http://www.hamline.edu/~lupus/articles/Pregnancy_in_Lupus.html
good luck to you both!
hugs, from Shelagh