 |
 | Home | Contact Us | FAQ | Search & Site Map | Link to Us |
 | Sign In | Join | Other 45 Sites in Network |
Medical Forum / General / Laboratory / August 2003measures of blood volume
Is there any lab measure or combination of lab measurements to determine blood volume?++Hematocrit seems the closest I can think but is it reliable? Perhaps a combination of measurements like albumin, etc.?++These don't really seem to get at what I'm looking for which is total blood volume.++The gold standard is probably a physical measurement but looking for lab.++Thanks! -------------- ?????? ???????? KORNET ------------- Not a practical one, though a isotope was used some decades ago. Perhaps nuclear med still does it, but we always considered one of those useless test that was once trendy. > Is there any lab measure or combination of lab measurements to determine blood volume?++Hematocrit seems the closest I can think but is it reliable? Perhaps a combination of measurements like albumin, etc.?++These don't really seem to get at what I'm looking for which is total blood volume.++The gold standard is probably a physical measurement but looking for lab.++Thanks! > -------------- ?????? ???????? KORNET ------------- > Not a practical one, though a isotope was used some decades ago. Perhaps > nuclear med still does it, but we always considered one of those useless > test that was once trendy. Exactly - it was measured because it could be. The "why" never came into it. MB > > Not a practical one, though a isotope was used some decades ago. Perhaps > > nuclear med still does it, but we always considered one of those useless [quoted text clipped - 3 lines] > > MB Dye dilution is the simplest method. As to why for adults I can't think of a good reason but my wife worked a few years ago for a group looking at blood volume in newborns with cerebral palsy. -- Mike Collins UK Mikecheatherc@oakwellmount.freeserve.co.uk Thanks for the notes everyone, one recommendation I will play with is adjusting 1/hematocrit for either (red blood cell volume) OR (red blood cell count) since hematocrit is the % RBV/total volume. I'll have to look around for prevalidated info.. Anyway it is interesting since I've found one article that argued that blood volume is *reduced* in hypertension: This is paradoxical because cardiac output is high. I haven't finished the article yet, anyway so my thinking is hypertension is mostly due to lack of vascular distention (resistance=endothelial disfunction) - like the mechanism for stress-induced hypertension is this. So now I'm left to guess why CO + SV is raised in hypertension my only guess is distribution of blood.. Anyway went way off topic, thx again.. > Thanks for the notes everyone, one recommendation I will play with is > adjusting 1/hematocrit for either (red blood cell volume) OR (red [quoted text clipped - 11 lines] > > Anyway went way off topic, thx again.. You do not measure total blood volume but rather total RBC mass by the radio chromium methods. There are several instances where you can get fictitious anemia such as a low hematocrit but in fact have a normal total RBC mass. This happens when plasma volume is increased but the RBC mass remains the same. Clinically this happens all the time during pregnancy. It is thought to be protective for minimizing rbc loss during delivery. Blood volume is lost but less RBC loss. This also happens with long distance runners and in any increase in circulating plasma volume. Wuzzy: >Is there any lab measure or combination of lab >measurements to determine blood volume?++ Is there a particular reason you are concerned with blood volume?  SignatureStev Lenon MT(ASCP) Confused? Listen to the music play! Save a cow, eat a PETA member slenon@tampabay.rr.com http://web.tampabay.rr.com/stevglo/index.html/slhomepage92kword.htm |
Reply to this Message |
 Sign In
 Join
 My Latest Posts My Monitored Threads My Blog My Photo Gallery My Profile My Homepage Start New Thread Enable EMail Alerts Rate this Thread
|
©2008 Advenet LLC Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.