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Medical Forum / Diseases and Disorders / Herpes / May 2005

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What is the MAX safe Lysine Dosage??

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Tom - 14 May 2005 17:59 GMT
Hello,

I am taking 2000 mg of Lysine per day all because my doctor doesn't think
the severity of my genital herpes condition needs Valtrex. I find that the
Lysine has been a life saver because without it I would have been in severe
pain from the herpes. I am wondering if there are any long term
consequences. I called the Vitamin World store and the counter person told
me that only 4000 mg or higher have limits on how long you can take them,
but yet a source online said that even taking 2000 mg per day should be
limited to 6 months then brought down to 1000 mg per day as a maintenance
dose for herpes. When calling the pharmacy or talking to my doctor they told
me they didn't know. Does anyone know if there is a set limit? I just don't
want to be taking this for a long period of time and then find out my liver
is about to go because I took too much lysine.

Thanks,
Tom
M2slo2cht@nospam.invalid - 14 May 2005 19:11 GMT
>Lysine has been a life saver

Glad to hear that because It doesn't help at all for many people. In
fact, it increases activity for some. That whole lysine/arginine ratio
thing seems to be a very inexact science. Lots of people can load up
on arginine with no ill effect at all.  Everybody's different.

>Vitamin World store and the counter person told
>me that only 4000 mg or higher have limits on how long you can take them,
>but yet a source online said that even taking 2000 mg per day should be
>limited to 6 months

Yep, there's lots of conflicting info about the stuff. I haven't seen
a study on it lately but one reliable source I've read claims that
anything less than 3000mg per day won't really do any good for herpes.

> I just don't
>want to be taking this for a long period of time and then find out my liver
>is about to go because I took too much lysine.

My understanding is that it's a fairly benign substance but ...who
knows.  Keep us posted if/when you find some interesting info.

M2
Tom - 15 May 2005 02:47 GMT
Well it does help me in terms of making the outbreaks a little less severe,
but not much more than that. I do know that after taking it from times when
I wasn't taking it, has brought on the blisters, so maybe that's what you
are referring to?

I heard that 1000 mg is maintenance and 2000-3000 is for use in prevention.

As far as arginine...well lets put it this way...if I have chocolate, coffee
and nuts I will almost certainly have an outbreak in about 5 days following
it. I noticed that taking lysine has reduced the symptoms but not more than
that. Now that the primary is over I still get outbreaks but they are alot
less severe, although some of the prodrome pain in the thighs and lower back
is pretty painful still.

> >Lysine has been a life saver
>
[quoted text clipped - 20 lines]
>
> M2
M2slo2cht@nospam.invalid - 15 May 2005 05:10 GMT
Just re-read my post and realize it sounded a bit on the negative
side. Sorry about that. Sometimes it just doesn't come out the way
it's supposed to. Obviously, Lysine works for quite a few people.

I went to a seminar a couple of years ago and heard the lady who wrote
the book (literally. She was selling the books at the seminar) on
Lysine/Arginine ratios and its effect on herpes. She's a nurse and had
done quite a bit of research on the subject. Anyhow, the theory on why
Lysine works, if I recall correctly, is as follows:
1)  HSV needs arginine to replicate
2)  Lysine displaces Arginine in the body.
3) The body can make it's own Arginine but can't make Lysine,
soooo....
4) the body hordes lysine whenever it's made available. The more
Lysine it hoards, the more arginine it simultaneously displaces
5) Once the body has little or no arginine, HSV can't replicate.
..... at least that's the theory.

>after taking it from times when
>I wasn't taking it, has brought on the blisters, so maybe that's what you
>are referring to?

hmm... not sure what you mean. But what I meant was, according to a
few people I've talked with, taking Lysine daily over a period of time
seemed to increase the frequency of their outbreaks during that time.
Then their outbreak frequency would lessen when they stopped taking
Lysine. Granted, that's anecdotal from an extremely small sample so
take it for what it's worth.

>I heard that 1000 mg is maintenance and 2000-3000 is for use in prevention.

Sounds like a good consensus. That's what's on a couple of reliable
sites. And I've also seen that toxicity levels haven't been
scientifically determined.

>As far as arginine...well lets put it this way...if I have chocolate, coffee
>and nuts I will almost certainly have an outbreak

It's a trigger for lots of folks. Wish all triggers had a antidote as
simple as Lysine.

M2
Tom - 15 May 2005 23:27 GMT
> Just re-read my post and realize it sounded a bit on the negative
> side. Sorry about that. Sometimes it just doesn't come out the way
> it's supposed to. Obviously, Lysine works for quite a few people.

No problem, I didnt take it in a negative way.

> I went to a seminar a couple of years ago and heard the lady who wrote
> the book (literally. She was selling the books at the seminar) on
[quoted text clipped - 9 lines]
> 5) Once the body has little or no arginine, HSV can't replicate.
> ..... at least that's the theory.

That's probably why after taking Lysine the symptoms are more mild from what
I still get. If the herpes cannot replicate it doesn't cause move through
the nerves and doesn't cause the nerve irritations and pain. Don't get me
wrong, even while taking 2000 mg per day I still get symptoms and have
outbreaks, but the symptoms are more bearable. Instead of being in all out
pain and aching in the thighs, lower back and extreme itching and throbbing
sensations, I am feeling a little more comfortable, but I can still feel it
happing. I guess I am one of those people that has severe herpes pain,
because I have alot of pain almost all the time, like a constant reminder,
but with the Lysine its not as bad.

Tom
Angela S. - 17 May 2005 16:10 GMT
> I am taking 2000 mg of Lysine per day all because my doctor doesn't think
> the severity of my genital herpes condition needs Valtrex.

That's interesting because Lysine is not an antiviral medication used to
treat Herpes Simplex Virus.

> I find that the
> Lysine has been a life saver because without it I would have been in
> severe
> pain from the herpes. I am wondering if there are any long term
> consequences.

Too much Lysine is not good for you and can actually cause your body tons of
harm.

>I called the Vitamin World store and the counter person told
> me that only 4000 mg or higher have limits on how long you can take them,
> but yet a source online said that even taking 2000 mg per day should be
> limited to 6 months then brought down to 1000 mg per day as a maintenance
> dose for herpes.

Once again.. Lysine is not a herpes antiviral medication. It doesn't reduce
asymptomatic shedding. It doesn't cut transmission rates in half. It doesn't
reduce the frequency or intensity of flare ups either.

>When calling the pharmacy or talking to my doctor they told
> me they didn't know. Does anyone know if there is a set limit? I just
> don't
> want to be taking this for a long period of time and then find out my
> liver
> is about to go because I took too much lysine.

If you want to talk to a herpes expert..  head on over to WebMD and ask
Terri Warren about all of this:

http://boards.webmd.com/topic.asp?topic_id=90

You might also check out a post that I wrote here:

http://www.yoshi2me.com/ipw-web/bulletin/bb/viewtopic.php?t=656

It's about Vitamins, Minerals, Amino Acids and the Arginine Theory.

Take Care,

Angela :)
M2slo2cht@nospam.invalid - 17 May 2005 19:18 GMT
Yoshi  writes:
>You might also check out a post that I wrote here:
>http://www.yoshi2me.com/ipw-web/bulletin/bb/viewtopic.php?t=656
>It's about Vitamins, Minerals, Amino Acids and the Arginine Theory.

Hi Yosh....
I couldn't get there with the link, even after I registered and logged
in.
I get the message:
"The topic or post you requested does not exist"

Is there another way to get there? Like "Jump to...." ... uh ... which
group?... and which message?... like that?

Thanks,
M2
Angela S. - 19 May 2005 15:23 GMT
M2,

You could see this thread even after you registered?

http://www.yoshi2me.com/ipw-web/bulletin/bb/viewtopic.php?t=656

Tell you what..

Just go to the folder titled "Herpes Simplex Virus (HSV)"

You should be able to find the stickie at the top of the page..

Let me  know if you still have trouble seeing it, ok?

Angela :)

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> Yoshi  writes:
>>You might also check out a post that I wrote here:
[quoted text clipped - 12 lines]
> Thanks,
> M2
M2slo2cht@nospam.invalid - 19 May 2005 16:38 GMT
Yosh writes:
>You could see this thread even after you registered?
>http://www.yoshi2me.com/ipw-web/bulletin/bb/viewtopic.php?t=656

Nope.  I could *not* either before I registered or after. It would
only take me to the "log in" page.

>Just go to the folder titled "Herpes Simplex Virus (HSV)"
>You should be able to find the stickie at the top of the page..
>Let me  know if you still have trouble seeing it, ok?

Ok, got there that way. Thanks  :-)

M2
M2slo2cht@nospam.invalid - 19 May 2005 16:54 GMT
Yosh writes:
>>You should be able to find the stickie at the top of the page..

M2 writes:
>Ok, got there that way. Thanks  :-)

By the way.... what's a stickie??

M2
Angela S. - 19 May 2005 20:46 GMT
> By the way.... what's a stickie??

It's those posts that are stuck at the top of the page as a type of service
announcement.

Angela :)
M.L.S. - 20 May 2005 02:02 GMT
>Yosh writes:

>>>You should be able to find the stickie at the top of the page..

>By the way.... what's a stickie??

Hey, this is a family group!

      ;-)

Mike
Perl Molson - 18 May 2005 10:46 GMT
> Hello,
>
[quoted text clipped - 13 lines]
> Thanks,
> Tom

Tom, I can recommend you or others to use Lysine suplemments only after
you've
tried all the other suplements etc.

I've found that, when used as a last resort, Lysine can be
very efective.
After several years of trying lots of folk remedies
while eating high Arginine containing foods during this time,
apparently my body has learned to cope with the herpes virus.
Suplementing at one point in time, for the first time, with Lysine,
I could have seen a total effectiveness in the ability of my body
to fight the virus.

In other words, improve your immune system, cleanse your
internal organs, blood, skin, etc and then add Lysine to your body.
The former part can last several years, until the later part, the use
of Lysine suplemments is needed.
At such point in time, you will only require small ammounts of Lysine.

Another interesting aspect of trying to improve your body's
resistance to herpes virus is to try to change the actual triggers
occasionally; for example, if you see that certain nuts are triggers,
try eating chocolate for a while, then try orange juice, and so on.
Use variation in your approaches.
Too much of anything is of no good for our bodies.
Provided we are not alergic to some of the mentioned foods (you don't
seem to be as I reckon),
coping with them can be done by increasing gradually.

Pay attention to these aspects and you will see results,
that before seemed impossible.
You will get to a point when you will be able to eat whatever you wish
without getting any herpes outbreaks whatsoever (as you've wrote,
after 5 days or so, after you ingest high arginine containing foods you
will get outbreaks).

Indeed, variation is one of the secrets in trying to deal with the
virus.
There is no magic pill so far, to my knowledge.
Nonetheless, our bodies are fantastic
machineries that can improve their abilities over time.
Pay close attention to what you eat and drink etc, how your skin
reacts to it.

Perl von Molson
Tom - 19 May 2005 04:14 GMT
Thanks everyone for the info. I know Lysine is not an antiviral and doesn't
stop shedding, nor does it stop the frequency of my outbreaks, but I DO
notice that it lessens the severity. If I wasn't taking it the nerve pain in
the lower back and legs would be almost unbearable. That's where my problem
symptoms are. The moderate symptoms are the tingling sensations and the
burning and itching, the less problematic symptoms are the blisters which in
my case are mild. Nearly all of my pain is on the upper and inner thigh area
and near the lower back and groin.

I not sure where Angela is getting the information on Lysine being
dangerous, because so far I haven't seen any information about that. I would
like to know though because if I am taking it I need to know the facts, but
it is also true that cleansing the body could be good as Perl stated.

Thanks,
Tom

> > Hello,
> >
[quoted text clipped - 69 lines]
>
> Perl von Molson
Angela S. - 19 May 2005 15:26 GMT
There is a book called "Managing Herpes - How to live and love with a
chronic std" written by Charles Ebel and Anna Wald. You can find this and
other herpes informational books over on
www.yoshi2me.com/herpes-hpv-book.html If you don't have a copy of this book
and you want to learn more about herpes - I highly recommend getting a copy
for your home library.

Here is a little snippet from the book:

The consensus in the scientific community is that lysine supplements in
particular have no inherent value. Experts also say that if you feel your
diet is deficient in some way and you want to take a supplement, the best
bet is a broad-spectrum, multivitamin formula that meets the Recommended
Daily Allowance (RDA) for the nutrients listed. According to many experts in
the field, nutrition is a complex interaction of verious elements, and
people are best served by eating a balanced diet that gives them all the
essential nutrients from real food. (We do need lysine, and a balanced diet
probably contains something on the order of 500 mg a day.) On the other
hand, megadoses of any one amino acid or vitamin can easily throw the body's
chemical system out of balance.

At one time, advocates of lysine also suggested restricting dietary intake
of another amino acid, arginine, which is found in lots of common foods,
among them chocolate, nuts, corn, and beer. Some people have found that, for
them, arginine-rich foods seem to trigger outbreaks. Nutritional research in
recent years, however, show that arginine actually enhances immune function
and helps people resist some infections. It's been tested on burn patients,
for example, and has been shown to lower rates of secondary infection.

Angela :)

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> Thanks everyone for the info. I know Lysine is not an antiviral and
> doesn't
[quoted text clipped - 19 lines]
> Thanks,
> Tom
M2slo2cht@nospam.invalid - 19 May 2005 16:38 GMT
>"Managing Herpes - How to live and love with a
>chronic std" written by Charles Ebel and Anna Wald.

Got mine at an Indy Event. Everybody that registered received one.
I agree, it's an excellent book and a good addition to any library.

M2
Angela S. - 19 May 2005 20:46 GMT
And VERY hard to argue against! lol

Angela :)

>>"Managing Herpes - How to live and love with a
>>chronic std" written by Charles Ebel and Anna Wald.
[quoted text clipped - 3 lines]
>
> M2
Tom - 19 May 2005 23:54 GMT
Hi Angela,

I actually do have a copy of that book and I found it very informative. As
far as the mega doses of Lysine...I wonder what defines a megadose? I don't
always eat a balanced diet, but lets say I did and had 500 mg that way and
then an additional 2000 mg. So how do I know what am is doing is too much
and also for too long?

By the way, I really like your web site. I'm going to register. I was
looking at it a little while I was at work today, and checking out the
success stories about people with herpes.

Thank you,
Tom

> And VERY hard to argue against! lol
>
[quoted text clipped - 7 lines]
> >
> > M2
Angela S. - 22 May 2005 20:46 GMT
> Hi Angela,

Hi Tom! :)

> I actually do have a copy of that book and I found it very informative. As
> far as the mega doses of Lysine...I wonder what defines a megadose? I
> don't
> always eat a balanced diet, but lets say I did and had 500 mg that way and
> then an additional 2000 mg. So how do I know what am is doing is too much
> and also for too long?

I would definitely encourage you to discuss all that with  your doctor. Your
doctor will be able to tell you what a mega dose of Lysine would be.. ya
know?

> By the way, I really like your web site. I'm going to register. I was
> looking at it a little while I was at work today, and checking out the
> success stories about people with herpes.

Wow ~ thanks Tom. I'm glad you are enjoying the site.

Angela :)

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Tom - 24 May 2005 00:36 GMT
Now maybe you can tell me how to register, because I am having trouble
finding a way to do that.

Thanks,
Tom

> > By the way, I really like your web site. I'm going to register. I was
> > looking at it a little while I was at work today, and checking out the
[quoted text clipped - 3 lines]
>
> Angela :)
 
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