> the good way, either.
>> Where is your information that lysine displaces arginine in a one to
>> one ratio?
>> Or that the body will automatically select lysine for its processes
>> instead of arginine when an abundance of arginine is readily
>> available?
>"Lysine, an analog of arginine, as an antimetabolite, antagonized the
>viral growth-promoting action of arginine"
>Is this clear enough, Mike?
Not exactly, Perlie. See further below.
>if not:
>an·tag·o·nize Audio pronunciation of "antagonize" ( P )
>Pronunciation Key (n-tg-nz)
>tr.v. an·tag·o·nized, an·tag·o·niz·ing, an·tag·o·niz·es
> 2. To counteract.
>Main Entry: coun·ter·act
>Pronunciation: "kaunt-&-'rakt
[quoted text clipped - 3 lines]
>counteract disease before medical science comes into play -Havelock
>Ellis> -coun·ter·ac·tion
>Relation of arginine-lysine antagonism to herpes simplex growth in
>tissue culture.
>Griffith RS, DeLong DC, Nelson JD.
>In the studies conducted, arginine deficiency suppressed herpes simplex
>virus replication in tissue culture. Lysine, an analog of arginine, as
[quoted text clipped - 3 lines]
>particularly during periods of stress, should abstain from arginine
>excess and may also require supplemental lysine in their diet.
>PMID: 6262023 [PubMed - indexed for MEDLINE]
>http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra
ct&list_uids=6262023
It's hard to tell just from the short abstract, but the authors do
speak in the context of an "arginine deficiency". They also report
"in vitro" data instead of "in vivo".
I see nothing in there establishing that lysine "antagonizes"
against arginine on one a one to one basis.
And there are still those old studies which couldn't award L-lysine
any more of remedial factor but in about 30% of cases, which doesn't
speak very highly of that alleged antagonizing factor.
I do like your new word, though. I doubt that I'll get much chance
to use it in the medical sense, but I like it, anyway.
>> Or that an *individual* performing this kind of experiment can
>> determine anything other than how easy it is to fool oneself about
>> such things?
>You need someone to tutor you for everything, don't you, Mike?
I don't need to be tutored on how to eat Big Macs and drink Cherry
Coke®!!! (as it so happened - "as it was meant to happen" - I
ended up, quite by accident, with a can of Diet Cherry Coke in my
hand last night. It was delish. It antagonized my blues away. ;-)
>> Half the strategy in becoming aware of the *alleged* role of lysine
>> and arginine in the herpes viral replication cycle is to *reduce*
>> arginine intake. As tenuous as the supposed relationship is between
>> arginine and lysine, one would common-sensibly expect that inducing
>> EXTRA arginine into the body would make it that much more difficult
>> to discern any sort of helpful pattern.
>My focus is on what takes herpes out of the dormant state, rather then
>what would keep the viral shedding level close to zero.
>I have used all of my options in trying (and hoping it works)
>to get rid of the asymptomatic shedding, the remained problem is
>eventually
>the viruses that become reactivated from the dormant state in ganglia.
>Consider this for a minute, Mike!
>if, as you say, increased arginine intake would contribute to
[quoted text clipped - 3 lines]
>LOCATED MOSTLY ON THE SHEDDING AREAS, (AFTER USING THE AXONAL TRANSPORT
>MECHANISM)?
That's the two dollar question, Perlie, but I would suppose that the
same system that delivers the oxygen and other building blocks to
all cells, delivers something useful to the HSV virus when it drops
off whatever the neuron needs to maintain its health.
I don't think anyone has ever suggested that arginine is the sole
agent fueling the HSV replicatin' cycle.
>DON'T TELL ME THAT THE VIRIONS WERE USING ARGININE INSIDE THE GANGLIA!
>NO!
>THE ONLY WAY ARGININE AFFECTS THE HERPES GROWTH IS ONCE ALREADY THE
>VIRUS IS SHEDDING.
If you say so, Big P. And I'm sure that arginine isn't the only
item in the body's vast store to be grabbed up and put to use.
Arginine is just one of the very few things that the human host can
regulate (very slightly) by being careful of what it eats.
>BEFORE THAT, THERE IS SOMETHING ELSE THAT WOULD TAKE THE VIRUS FROM THE
>DORMANT STATE.
Yes, YES! There might even be more than one SOMETHING ELSE. There
might be a very complicated, involved trigger mechanism.
>I SUSPECT MAYBE HORMONAL IMBALANCE IN OUR BODY WOULD POSSIBLY CAUSE
>SUCH A TRIGGER.
There ya go. You've almost found your cure again. I'm very proud
of you, Perlie.
>>Even the formal studies on
>> such matters were rather equivocal in their findings, and they had
>> common sense and a population of more than one working for them.
>> Other than that, Perlie, as usual, you are <undefined amount>%
>> correct.
>> ps. Reckless adherence to any of Perlie's recommendations, past or
>> present,
>I only suggest, I do not recommend.
I'll try to remember that.
> could lead to unexpected results. And not "unexpected" in
>> the good way, either.
>Either way, the results are a good thing.
Mike
steve692884@duskmail.com - 22 Mar 2005 16:02 GMT
msoja9@newsguy.com wrote:
> Not exactly, Perlie. See further below.
> It's hard to tell just from the short abstract, but the authors do
[quoted text clipped - 27 lines]
> I'll try to remember that.
> Mike
Thank you
steve692884@duskmail.com