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Medical Forum / Diseases and Disorders / Herpes / June 2006

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Cranberries!

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Gadge - 19 Oct 2004 00:12 GMT
The free newspaper I read on my way to work had an article about a study
done on a compound extracted from a certain type of cranberry (see below).
Though I don't think we should all be drinking loads of cranberry juice or
anything!  - I have no idea about this research, who carried it out, or the
scientific background of the person that wrote the article, but I thought
you guys might be interested.  Has anyone else heard anything about this?
Didn't get much from a quick google...

-------------

Cranberry treatment for herpes

The humble cranberry may offer a new way to fight an incurable sex disease
which affects ten percent of Britons.  A compound extracted from the alpine
version of the fruit suppresses the virus that causes genital herpes, making
it harder for it to enter human cells, scientists say.

Cranberries also ease later stages of the infection by stopping the virus
multiplying.  Researchers in Taiwan successfully tested the compound on
monkeys.  Researcher Chun-Chin Lin hailed the study as a breakthrough
'meiting further investigation'.

Ther is no cure for the herpes virus, which lies dormant in the body for
long periods before breaking out at intervals to cause symptoms such as
itching and sores.

Cranberries - frequently used in juices, jams and sauces - are already
credited with a wide range of health effectes including fighting stomach
ulcers and heart disease.

--
Gadge
Wanda - 19 Oct 2004 13:36 GMT
I know that drinking Cranberry juice helps me when I have a kidney or
bladder infection. Thats all I know about it.
Wanda

> The free newspaper I read on my way to work had an article about a study
> done on a compound extracted from a certain type of cranberry (see below).
[quoted text clipped - 31 lines]
> --
> Gadge
Gadge - 19 Oct 2004 19:29 GMT
> I know that drinking Cranberry juice helps me when I have a kidney or
> bladder infection. Thats all I know about it.
> Wanda

I know I like the taste of it - anything else is just a bonus!

--
Gadge
Tim Fitzmaurice - 21 Oct 2004 14:39 GMT
> I know that drinking Cranberry juice helps me when I have a kidney or
> bladder infection. Thats all I know about it.
> Wanda

On topic review here
Zirk MM. Aluko RE. Taylor CG.
Cranberry (Vaccinium Macrocarpon) proanthocyanidins and their effects on
urinary tract infections.
Current Topics in Nutraceuticals Research. Vol. 2(3)(pp 153-160), 2004.

Some key sentences from the abstract
"Recently it has been shown that the beneficial effects of cranberries in
prevention of UTI are due to two of its constituents, fructose and
proanthocyanidins (PAs), which function as anti-adherence agents."

"PAs are stable polyphenolic compound; and possess various qualities
including antiviral, antibacterial, anti-adhesive, and antioxidant
properties".
(note there is the right set of compounds to have potential for HSV
acivity and to go look for it)

and for you Wanda - the last sentence may be of interest.
"Administration of cranberry juice or cranberry concentrate tablets have
been shown to reduce the recurrence and antibiotic requirements of UTI in
women, though there is no conclusive evidence that it can be used as a
curative agent. Cranberry tablets have been shown to have similar
prophylactic effectiveness but more cost effective when compared to the
juice"

Tim
--
When playing rugby, its not the winning that counts, but the taking apart
ICQ: 5178568
Tim Fitzmaurice - 21 Oct 2004 14:34 GMT
> The free newspaper I read on my way to work had an article about a study
> done on a compound extracted from a certain type of cranberry (see below).
> Though I don't think we should all be drinking loads of cranberry juice or
> anything!  - I have no idea about this research, who carried it out, or the
> scientific background of the person that wrote the article, but I thought
> you guys might be interested.  Has anyone else heard anything about this?

Not on viruses specifically that i've seen, but its got some pretty active
compounds in it and its not unreasonable to suggest some might show
antiviral activity.

Proanthocyanidins I think are the normally named culprit. Interacts
nastily with warfarin but it wouldnt be alone in interacting with and
changing the potential of other drug compounds (grapefruitjuice does some
thing with certain meds)

Most work seems to be on antibacterial action, a little on some
antiproliferative effects that is working towards antitumour work. It
might be this is the first work and just released so it hasn't got into
the database yet (takes about 3-4 weeks sometimes) and if its the first
look at antiviral activity with the juice then there will be precious
little unless you can name the journal, then I may be able to pull the
paper.

Tim
--
When playing rugby, its not the winning that counts, but the taking apart
ICQ: 5178568
Chris - 09 Jun 2006 01:23 GMT
> The free newspaper I read on my way to work had an article about a study
> done on a compound extracted from a certain type of cranberry (see below).
[quoted text clipped - 28 lines]
> --
> Gadge

Well, I think that any time a healthy diet is introduced, the body
creates a stronger immune system.  Whether it's cranberries, or anything
else that's not full of saturated, it's bound to do you good.

I know when I fill up on fresh juice, work-out regularly, and cut back
on red meats, my outbreaks disappear, but when I get back into my
unhealthy mode, they come rather frequently.

-Chris
grant - 09 Jun 2006 01:28 GMT
Excellent, Chris!  I've been doing the diet and exercise thing for years.
It's the best thing for your immune system.

ar

>> The free newspaper I read on my way to work had an article about a study
>> done on a compound extracted from a certain type of cranberry (see
[quoted text clipped - 44 lines]
>
> -Chris
 
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