By the way, I'm not a Dr of medicine! I've been diagnosed with
shingles and prescribed aciclovir 800mg 5 times a day. Does anyone
know if my taking of this anti viral drug will lessen my body's
immunity to the zoster virus in future by making the fight easier as
it were?
Does anyone know if all cases of shingles require this treatment, and
can anyone tell me how the drug works? All replies gratefully
received.
Thanks
Tim Fitzmaurice - 08 Dec 2003 13:05 GMT
> By the way, I'm not a Dr of medicine! I've been diagnosed with
> shingles and prescribed aciclovir 800mg 5 times a day. Does anyone
> know if my taking of this anti viral drug will lessen my body's
> immunity to the zoster virus in future by making the fight easier as
> it were?
No, you body has spent the last X number of years (since you caught
chickenpox or were exposed to it - likely as a child) developing, refining
and maintaining its immune response to the virus. Its not a new infection
and also the immune system will get involved in the final clearing out of
the infection so its system of recognition and reaction will get re-primed
during this outbreak anyway.
> Does anyone know if all cases of shingles require this treatment,
Well its probably a good idea since the literature indicates that
aggressive treatment may help limit certain nasty follow-on effects like
post herpetic neuralgia. As you are probably aware in most people the
outbreak itself can be incredibly irritating to very painful and reducing
that in itself it likely a good idea. Also the antiviral can limit the
viral shedding going on and that in itself helps limit transmission
possiblities.
THe drug works by mimicking one of the letters of the virus' DNA code
(the G's in fact). They get included in the strand instead of the normal G
and that blocks the replication of the virus DNA which in turn means no
viable virus particles to go on. It avoids this happening in uninfected
cells and so it doesn;t affect host DNA replication because the first step
in the biochemistry requires the presence of a virus gene and so happens
specifically in virus infected cells.
TIm
--
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Grant - 08 Dec 2003 17:30 GMT
Yes, most people are given one of the herpes antivirals when diagnosed with
shingles. Someone else will have to tell you how it works, though. :)
I don't believe that taking the medication will lesson your immunity. I
don't have any proof of that, though.
No case of shingles HAS to be treated. It will, eventually, go away. But
the pain is pretty severe and the meds help.
ar
> By the way, I'm not a Dr of medicine! I've been diagnosed with
> shingles and prescribed aciclovir 800mg 5 times a day. Does anyone
[quoted text clipped - 5 lines]
> received.
> Thanks
Dr_weekswages - 09 Dec 2003 21:25 GMT
> Yes, most people are given one of the herpes antivirals when diagnosed with
> shingles. Someone else will have to tell you how it works, though. :)
[quoted text clipped - 12 lines]
> > immunity to the zoster virus in future by making the fight easier as
> > it were.
Thanks for these anwswers. Tim, it was especially interesting to hear
how the drug works.
> > Does anyone know if all cases of shingles require this treatment, and
> > can anyone tell me how the drug works? All replies gratefully
> > received.
> > Thanks