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Medical Forum / Diseases and Disorders / Herpes / October 2007

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Herpes Antibody Question

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Rich - 07 Oct 2007 03:35 GMT
Hi Everyone, I am getting conflicting medical information. If a pesron
scores high and positive for herpes antibodies does that confirm 100%
that the person is in fact infected to the herpes virus. If not what
other medical conditions would cause a human to produce high herpes
antibodies? I appreciate any medical web links that relate to
answering this question also. Thank you.
Rich
M2slo2cht@nospam.invalid - 07 Oct 2007 15:14 GMT
>If a pesron
>scores high and positive for herpes antibodies does that confirm 100%
>that the person is in fact infected to the herpes virus.

More like 99%.
There's always that chance that somebody in the lab screwed up.
Positive results are usually pretty accurate.

>I appreciate any medical web links that relate to
>answering this question also.

Go here then click on "Diagnosing Genital Herpes"

http://www.westoverheights.com/genital_herpes/handbook/view_the_chapters.html

M2
Yoshi2me - 07 Oct 2007 22:19 GMT
> Hi Everyone, I am getting conflicting medical information. If a pesron
> scores high and positive for herpes antibodies does that confirm 100%
> that the person is in fact infected to the herpes virus.

High OR low if you have antibodies for HSV then you have HSV.

> If not what
> other medical conditions would cause a human to produce high herpes
> antibodies?

I don't understand what you're trying to figure out because people that have
antibodies to the Herpes virus have herpes. High or low it doesn't matter
because antibodies for herpes = herpes.

> I appreciate any medical web links that relate to
> answering this question also. Thank you.

Did you try to google "Herpes Antibodies" ??

Hang in there,

Angela ;)

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Rich - 07 Oct 2007 22:30 GMT
> > Hi Everyone, I am getting conflicting medical information. If a pesron
> > scores high and positive for herpes antibodies does that confirm 100%
[quoted text clipped - 18 lines]
>
> Angela ;)

Hi Angela,
One reason I am asking this question is because a doctor wrote to me
with this reply. "Demonstration of active HSV1 infection requires
indentifcation of the actual virus, not the antibody". I tend to
disagree with this because the herpes virus can be actively infecting
a person internally in the central nervous system without showing skin
lesions at the time. I think this correct. If I have high HSV1
antibodies he is saying that is not proof of an active infection. It
would seem to me that once infected herpes is always active to some
extent. Maybe some one can claify this. HSV1 antibody level was 38.4.
Negative for HSV2.
Rich
Yoshi2me - 08 Oct 2007 14:28 GMT
If a person has antibodies to HSV then that means the person has HSV. BUT,
that doesn't necessarily mean that the virus is always active and present on
the surface of the skin. We are not always contagious if that is what you
meant.

Angela ;)

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M2slo2cht@nospam.invalid - 08 Oct 2007 15:41 GMT
>a doctor wrote to me
>with this reply. "Demonstration of active HSV1 infection requires
>indentifcation of the actual virus, not the antibody".

Without knowing the context, it's hard to know what he meant. But this
statement alone doesn't make sense.

>I tend to
>disagree with this because the herpes virus can be actively infecting
>a person internally in the central nervous system without showing skin
>lesions at the time. I think this correct.

Generally, "active infection" means "outbreak" or at least "shedding"
or "prodrome". Otherwise the infection is considered "dormant".

>If I have high HSV1
>antibodies he is saying that is not proof of an active infection.

Maybe not "active" infection but it's proof of infection nonetheless.

>would seem to me that once infected herpes is always active to some
>extent.

Nope. For most people it's dormant most of the time.

M2
Rich - 08 Oct 2007 21:46 GMT
On Oct 8, 10:41 am, M2slo2...@nospam.invalid wrote:
> >a doctor wrote to me
> >with this reply. "Demonstration of active HSV1 infection requires
[quoted text clipped - 22 lines]
>
> M2

Thank you for your replies. The use of the word 'dormant' with herpes
virus is ridiculous in my opinion. Just because there is no active
visbile skin lesion does not mean the virus is dormant. It can travel
to other parts of the body via the nervous system or how ever else it
travels. So, unless a person had x-ray vision that could precieve the
internal activity and movement of the herpes virus thought the body
the use of the word 'dormant' to me is totally unfactual. It reminds
me patients who are told by doctors that there cancer is in
'remission' or cancer free, then turn around and die months later from
an 'active' cancer. Doctors like to use words like dormant and
remission to soothe and ease a patients mind..not to properly
clinically express the real activity of a pathogen in the body.
Rich
M2slo2cht@nospam.invalid - 09 Oct 2007 00:05 GMT
>Just because there is no active
>visbile skin lesion does not mean the virus is dormant. It can travel
>to other parts of the body via the nervous system or how ever else it
>travels. So, unless a person had x-ray vision that could precieve the
>internal activity and movement of the herpes virus thought the body
>the use of the word 'dormant' to me is totally unfactual.

"Dormant" means "not active".  Not on the skin, not traveling the
nerve pathways, not causing symptoms, not creating new viruses. In
it's dormant state, it's residing in the Sachral Ganglia (in the case
of Genital Herp) not doing a thing. It can remain in that state
indefinitely and, in fact, spends most of it's life that way (if you
can call that a life) in most infected people. Granted, it can become
active without it's host realizing it but that doesn't make it's
dormant state "unfactual".

M2
Yoshi2me - 09 Oct 2007 12:21 GMT
M2 explained it a lot better than I did! ;)

> "Dormant" means "not active".  Not on the skin, not traveling the
> nerve pathways, not causing symptoms, not creating new viruses. In
[quoted text clipped - 4 lines]
> active without it's host realizing it but that doesn't make it's
> dormant state "unfactual".
Rich - 13 Oct 2007 23:16 GMT
> M2 explained it a lot better than I did! ;)
>
[quoted text clipped - 8 lines]
>
> - Show quoted text -

If 100 people infected with herpes with no skin lesions were lined up
naked in a row and 100 infectious disease doctors made indepenence
evalutaions on wheter each patient was dormant or active do you think
each infectious disease doctor's clipboard results would agree with
the other 99 if each patient was active or dormant?
Rich
M2slo2cht@nospam.invalid - 14 Oct 2007 14:44 GMT
>If 100 people infected with herpes with no skin lesions were lined up
>naked in a row and 100 infectious disease doctors made indepenence
>evalutaions on wheter each patient was dormant or active do you think
>each infectious disease doctor's clipboard results would agree with
>the other 99 if each patient was active or dormant?

I presume your question is rhetorical as I doubt 100 people could ever
completely agree on ANYthing.  My point was though, various studies
have shown that, on average, study subjects shed virus
asymptomatically on about 3% of the days in a year. Not necessarily
all day either, but at least for a few minutes. That's not very often.
Granted, each study will be a little different as each group of
subjects is different. Lots of ifs, ands, & buts involved.
I'm simply trying to point out that the Herpes Virus IS often in a
dormant state. Simply that.

M2
Rich - 15 Oct 2007 02:11 GMT
On Oct 14, 9:44 am, M2slo2...@nospam.invalid wrote:
> >If 100 people infected with herpes with no skin lesions were lined up
> >naked in a row and 100 infectious disease doctors made indepenence
[quoted text clipped - 13 lines]
>
> M2

M2,
If you would send me an email I would like to send you a link of
about 80 photos of systemic skin reaction of what appears systemic
herpe response to efudex.
RIch
M2slo2cht@nospam.invalid - 15 Oct 2007 13:26 GMT
>M2,
> If you would send me an email I would like to send you a link of
>about 80 photos of systemic skin reaction of what appears systemic
>herpe response to efudex.
>RIch

You can write to me at gmail dot com if you'd like. But I'd prefer you
post any links here (not photos, just a link), for the benefit of
anyone interested.

Efudex can cause skin irritation so it wouldn't surprise me if it
could trigger an outbreak. Same as any other skin irritation might.
However, I'd think accurately distinguishing herpes from the side
effects of Efudex in a photo would be fairly difficult. That's not
what you wanted *me* to do, is it? A culture type test would be needed
for that.

M2  <--- not a doctor. Just a guy who's been reading up and discussing
H for quite awhile.
Yoshi2me - 14 Oct 2007 17:33 GMT
> If 100 people infected with herpes with no skin lesions were lined up
> naked in a row and 100 infectious disease doctors made indepenence
> evalutaions on wheter each patient was dormant or active do you think
> each infectious disease doctor's clipboard results would agree with
> the other 99 if each patient was active or dormant?
> Rich

There are swab tests that can tell each doctor if each person is shedding or
not. I think it's done by PCR swabbing.

What is it you are trying to say exactly Rich?

Angela

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Rich - 15 Oct 2007 01:42 GMT
> > If 100 people infected with herpes with no skin lesions were lined up
> > naked in a row and 100 infectious disease doctors made indepenence
[quoted text clipped - 16 lines]
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Angela, I am simply trying to say that herpes not being visabaly
present or shedding on the skin does not discount its movement and
progression inside the body in some people.
RIch
Yoshi2me - 15 Oct 2007 13:00 GMT
Oh, ok.

Well, keep in mind that when the virus is not active it sleeps in the
ganglia either towards the bottom of the spine OR the top of the spine
depending on which type you have.

Best Wishes,

Angela ;)

> Angela, I am simply trying to say that herpes not being visabaly
> present or shedding on the skin does not discount its movement and
> progression inside the body in some people.
M2slo2cht@nospam.invalid - 15 Oct 2007 13:38 GMT
>Angela, I am simply trying to say that herpes not being visabaly
>present or shedding on the skin does not discount its movement and
>progression inside the body in some people.

Except for people with immune system problems, Herpes (Genital) only
travels nerves between the Sachral Ganglia and the surface of the skin
in the boxer shorts area. It doesn't wander through the entire body.
And Herpes isn't a progressive disease.

M2
Yoshi2me - 09 Oct 2007 12:20 GMT
> Thank you for your replies. The use of the word 'dormant' with herpes
> virus is ridiculous in my opinion.

Why? It just means that the virus is sleeping. In other words, it's not
active and present on the surface of the skin. Active and present on the
surface of the skin meaning that sometimes we can see and feel our outbreaks
and other times we can not.

> Just because there is no active
> visbile skin lesion does not mean the virus is dormant.

No, it doesn't mean that because then why would we have asymptomatic
shedding?

> It can travel
> to other parts of the body via the nervous system or how ever else it
> travels.

Uh,  no. The herpes virus doesn't do that. For those that have genital
herpes the virus lies in the nerve ganglia at the base of the spine. When it
becomes active it travels the nerve pathways to areas below the belt line.
(usually the boxer shorts area) For those that have oral hereps the virus
lies in the nerve ganglia at the top of the spine. When it becomes active it
travels the nerve pathways to areas above the neck line. (usually on or
around the mouth)

Herpes does NOT travel to other body parts in the way that you described.

> So, unless a person had x-ray vision that could precieve the
> internal activity and movement of the herpes virus thought the body
> the use of the word 'dormant' to me is totally unfactual.

Your understanding of the word dormant makes how you see this incorrect.

> It reminds
> me patients who are told by doctors that there cancer is in
> 'remission' or cancer free, then turn around and die months later from
> an 'active' cancer. Doctors like to use words like dormant and
> remission to soothe and ease a patients mind..not to properly
> clinically express the real activity of a pathogen in the body.

I've got some books you can order so that you can read up on the herpes
virus a bit more. This will help to ease all the confusion you seem to be
having. Also, there is no comparison between cancer and herpes so your
example is greatly flawed.

http://yoshi2me.com/herpes-hpv-books.html

Hang in there,

Angela

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mamazalama - 16 Oct 2007 21:12 GMT
Rich wrote:
>> It can travel
>> to other parts of the body via the nervous system or how ever else it
>> travels.

Yoshi2me responded:

> Uh,  no. The herpes virus doesn't do that. For those that have genital
> herpes the virus lies in the nerve ganglia at the base of the spine. When
[quoted text clipped - 4 lines]
> (usually on or around the mouth)
> Herpes does NOT travel to other body parts in the way that you described.

I have to agree with M2 when he said:
"Except for people with immune system problems, Herpes (Genital) only
travels nerves between the Sachral Ganglia and the surface of the skin
in the boxer shorts area. It doesn't wander through the entire body.
And Herpes isn't a progressive disease."

I am one of those people with immune system problems as well as Herpes 1 and
2, and as M2 mentioned above, my Herpes 2 (both genital and whitlow) wanders
wherever it wants.  I CAN get OB's just about anywhere and everywhere on my
body (which 'may' make it "a progressive disease" as it's constantly picking
out new locations.)
Usually, however, my OB's erupt in the same GENERAL location, but not exact.
Also, I can feel the Herpes moving around in my body, travelling from my
feet to my head!  My OB's are ALWAYS changing places, above and below the
waist.
Rich also said:

>> So, unless a person had x-ray vision that could precieve the
>> internal activity and movement of the herpes virus thought the body
>> the use of the word 'dormant' to me is totally unfactual.

I agree... mine is never 'dormant', always on the move - always "awake".

<SNIP>
 
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