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Medical Forum / Diseases and Disorders / Herpes / October 2003

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Herpes Simplex Virus Trigger Poll

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Perl Molson - 27 Oct 2003 03:43 GMT
http://dermatology.about.com/library/blherptrigpoll.htm

Stress and anxiety seem to be the major triggers (menstruation, the
same story).

It is quite remarcable, isn't it?

About Poll  

What triggers a herpes outbreak for you?

Anxiety  (59)  
9%


Fatigue  (34)  
5%


Fever  (17)  
2%


Sun exposure  (50)  
7%


Heat  (18)  
2%


Cold  (26)  
4%


A break in the skin  (32)  
4%


Starting my period  (78)  
12%


Stress  (239)  
37%


Other  (92)  
14%


Total Votes: 645


http://jvi.asm.org/cgi/content/full/75/2/750?view=full&pmid=11134288

Virus infection induces an antiviral response that is predominantly
associated with the synthesis and secretion of soluble interferon.
Here, we report that herpes simplex virus type 1 virions induce an
interferon-independent antiviral state in human embryonic lung cells
that prevents plaquing of a variety of viruses. Microarray analysis of
19,000 human expressed sequence tags revealed induction of a limited
set of host genes, the majority of which are also induced by
interferon. Genes implicated in controlling the intracellular spread
of virus and eliminating virally infected cells were among those
induced. Induction of the cellular response occurred in the absence of
de novo cellular protein synthesis and required viral penetration. In
addition, this response was only seen when viral gene expression was
inhibited, suggesting that a newly synthesized viral protein(s) may
function as an inhibitor of this response.
Grant - 27 Oct 2003 11:36 GMT
What's remarkable about this?  We've known this for a very long time.

ar

> http://dermatology.about.com/library/blherptrigpoll.htm
>
[quoted text clipped - 55 lines]
> inhibited, suggesting that a newly synthesized viral protein(s) may
> function as an inhibitor of this response.
M2slo2cht@Yahoo.com - 27 Oct 2003 13:36 GMT
I don't know about remarkable but I do find it surprising that "Sun
exposure" (7%) and "Fever" (2%) haven't gotten more votes. And I'm
surprised they didn't ask about "Colds".  After all, they are commonly
called "Cold sores" and Fever blisters". The "Cold" they DID ask about
appears to be the exterior temp kind rather than internal crappy
feeling with sneezing and runny nose.
Also, they left off "Friction". That one seems to be a popular one
from what I've read.

But the poll appears to be an informal non-scientific one so we can
only take it for what it's worth. I didn't see an indication of how
long they've had the poll going or how long before it ends.
M2

On Mon, 27 Oct 2003 10:36:53 GMT, hatetheviruses wrote:
>What's remarkable about this?  We've known this for a very long time.
>ar

Perl wrote:
>> http://dermatology.about.com/library/blherptrigpoll.htm
>> Stress and anxiety seem to be the major triggers (menstruation, the
>> same story).

>> It is quite remarcable, isn't it?
>> About Poll>>
[quoted text clipped - 20 lines]
>> 14%
>> Total Votes: 645
M.L.S. - 27 Oct 2003 14:54 GMT
>What's remarkable about this?  We've known this for a very long time.

Stress is the great malady of modern civilization.  I doubt there is a
single disease anywhere that isn't made worse by it.  But today I'm
going to try not to stress out about it.

Take care,

Mike
M.L.S. - 28 Oct 2003 15:39 GMT
>What's remarkable about this?  We've known this for a very long time.

Found on a web page this a.m.:

"The reason why worry kills more people than work is that more people
worry than work." --Robert Frost

Mike
 
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