> To be serious, I don't know of this, I'm sure it could be true though, some
> people are immune to HIV. I guess you can find immunity to many if not all
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>
> - Show quoted text -
Are some ppl really immune to aids?? or do you mean that they can
still get infected but just never get any symptons but still be
carriers. My dr said I'm also not a carrier she plain out said SEVERAL
times that I just can't get it or give it.
Tim Fitzmaurice - 29 May 2007 15:08 GMT
> Are some ppl really immune to aids??
Yes, apparently. There have been a few rare cases who despite exposure
seem not to have picked up HIV. There exists in virology the theoretical
construct of someone whose body just happens to mount the right response
at the right time to beat off a given virus. These people exist as case
reports asking whether they might be naturally immune - and no-one really
has a clue how to identify them or why they might be immune. The general
view its that its something in the innate immune system or weird stuff
happening at the mucosal surfaces.
The big one of these was a certain weird situation in the
prostitutes in Nairobi I think it was (yup, found the initial paper).
Fowke KR, Nagelkerke NJ, Kimani J, Simonsen JN, Anzala AO, Bwayo JJ,
MacDonald KS, Ngugi EN, Plummer FA. Resistance to HIV-1 infection among
persistently seronegative prostitutes in Nairobi, Kenya.
Lancet. 1996 Nov 16;348(9038):1347-51.
Now they still havent worked out why this happened - some papes indicated
some immune repsonses, others found IgA responses (which no blood test
would pick up) and used that to explain it....but in all they had no idea.
Also a number of these people who seemed resistant would go home, still
remain contactable by the study people whehn they returned and lose that
immunity when they came back to the city - suggesting a persistent
exposure might be necessary to produce and maintain the immunity...ie it
was situational.
They still havent worked out how that works, nor been able to convert it
to a protective method yet (to my knowledge which is a moderately rusty
with HIV).
Tim

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Grant - 29 May 2007 19:05 GMT
Yeah, I want to hear from your doctor how she can conclude this. To be
honest, I think she doesn't know what she's talking about.
ar
>> To be serious, I don't know of this, I'm sure it could be true though,
>> some
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> carriers. My dr said I'm also not a carrier she plain out said SEVERAL
> times that I just can't get it or give it.