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Medical Forum / Diseases and Disorders / Herpes / July 2006Question about shedding and spreading
Hello, I was just wondering if there is any possibility that herpes can be made worse by being intimate with a person who also has herpes and is having an outbreak. In other words, I am very attracted to this new woman I have been talking to. She has had HSV2 for 8 years and is on supressive valtrex because she gets very frequent outbreaks otherwise. I get 1 outbreak every 6-8 weeks now and don't have to be on valtrex. Is there anyway my condition could get worse by being intimate with a person that has more outbreak problems than I do? Like could it increase the viral population for me? Its probably a dumb question and I think the answer would be no, but just wondering. Al Hi Al ~ > I was just wondering if there is any possibility that herpes can be > made worse by being intimate with a person who also has herpes and is > having an outbreak. No. > In other words, I am very attracted to this new > woman I have been talking to. She has had HSV2 for 8 years and is on > supressive valtrex because she gets very frequent outbreaks otherwise. > I get 1 outbreak every 6-8 weeks now and don't have to be on valtrex. > Is there anyway my condition could get worse by being intimate with a > person that has more outbreak problems than I do? Since you both have genital herpes type-2 I would still say No. Is friction from sex a trigger for you Al? If it is a trigger that would be the only thing I could think of that would cause you to have more outbreaks. > Like could it > increase the viral population for me? Its probably a dumb question and > I think the answer would be no, but just wondering. It doesn't hurt to wonder and it's certainly not a dumb question. The answers that I provide are typical of healthy individuals... so keep that in mind too. I'm sure Tim, M2, and Ar will have more to share on this as well... See you on yahoo im, Angela :)  Signature"By opening up to a partner and talking about an STD diagnosis you are showing that you respect and care about yourself as well as the other person." Herpes Help http://yoshi2me.com/index.html Shut Up & Post! http://yoshi2me.com/phpbb/index.php Herpes Blog http://herpes-help.blogspot.com/ You think correctly. The standard theoretical answer is no. Now for the ifs, ands, & buts. Once you're infected, and there's been time enough to build immunity, assuming your immune system in normal and uncompromised, your immune system should be able to effectively combat any new exposure to the same virus. However, there exists different strains within the same type that may or may not throw a monkey wrench into the works. And remember, the two types don't offer much if any protection from each other. My unprofessional advice would be to make sure neither of you has a type the other doesn't have. Then, it couldn't hurt to just take precautions during outbreaks, even though risk of further transmission is practically zippity do da. M2 >Hello, >I was just wondering if there is any possibility that herpes can be [quoted text clipped - 9 lines] > >Al > You think correctly. The standard theoretical answer is no. Now for > the ifs, ands, & buts. [quoted text clipped - 10 lines] > is practically zippity do da. > M2 Okay thanks everyone for the information. I think my immune system is okay in general. I know I have hsv1 orally as well as the hsv2 genital, and she didnt say that she had hsv1 but she could have it orally as well. I guess there is always that chance that she could have that different strain of hsv2 and give me herpes again, but thats probably slim. I'm willing to take that chance, because I really like her alot and I am really glad we got to know one another. I'm unable to have kids and she got her tubes tied, so we don't have to worry about condoms, plus she hasnt been with anyone else she told me in a couple of years. Is there any transmission at all if a person is on supressive valtrex? I heard that with hsv2 its 4% asymtomatic so does that mean with hsv2 and valtrex its 2% or what? Thanks again, Al >Is there any transmission at all if a person is on supressive valtrex? Assuming a couple is discordant, yes, there's still a transmission risk. Suppression on Valtrex cuts the risk down significantly but doesn't completely eliminate it. >I heard that with hsv2 its 4% asymtomatic so does that mean with hsv2 >and valtrex its 2% or what? Not sure what you mean by that ^ but suppresive Valtrex cut transmission risk approximately in half for the group of discordant couples in one major study. M2 > Hello, > > I was just wondering if there is any possibility that herpes can be > made worse by being intimate with a person who also has herpes and is > having an outbreak. The traditional answer would be 'No because once infected you cannot normally be reinfected.' A few years ago it was noted by some fancy technology in Louisiana I think that the numberof DNA copies in the reservoir neurones went up over time. Is this new infections coming in or something else about how the virus reproduces before reactivation gets going in a big way. Now there has been a \n increasing body of evidence that autoinoculation and other reinfection events do occur. There is a review here that fairly old... Klein RJ Vaccine 1989, 7, p380-391 Reinfections and site-specific immunity in herpes simplex infections However this discusses posibilities rather than raging problems. At the time a fair amount of mouse work was being done and thiat might not allow you to go more than possibilities. The more recent paper I spotted was Roest et al, 2004, J. Med VIrol. Vol 73, p601-604 They were looking at what was happening in HSV1 genital herpes recurrence but found that in a reasonable proportional of cases (10% or so if the 2 out of 13 is accurate) there was more than opne strain popping up making it clear that reinfection at one site is clearly possible. What this doesnt even attempt to tell you is what effect this has on the biology around the event. It doesnt list such an important finding in the abstract suggesting they didnt see increased activity. SO while there is now the possibility of virus strains bouncing back and forth Ive not spotted anything indicating that it kicks off increased disease outbreaks. > increase the viral population for me? Its probably a dumb question and > I think the answer would be no, but just wondering. Oh its not a dumb question, but to be honest Im not sure if anyone has actually tried to examine this particular question, the 2004 paper was one of the few I found that really had the right technology to look at reinfection at one site and used it (another is Sakaoka et al, 1995, J Med Virol, vol46, p387-396)...thats all personal opinion of course - I havet yet done a really long mining session on the database to look for snippets buried in other papers. TIm -- When playing rugby, its not the winning that counts, but the taking apart ICQ: 5178568 |
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