unsuccessful completed interferon for hepatitis c treatment

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ingderogatis@libero.it - 15 Apr 2005 22:57 GMT

My father, aged 60, has completed an interferon + ribavirin treatment
that has lasted 10 months.
All seemed succesful, after 3 months since the end of the treatment
the virus was not detected.
After 5 months we've detected again the virus with higher values of
ferritin and transaminasis than the ones before the begin of the
treatment.

What to do now?
What happened? Why the virus became so active?
Is there any suggested treatment now that the virus should be still at
low concentrations, but more reactive?

please I am urgently looking for wise suggestions

thanks

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Selene Cordi - 22 Apr 2005 08:54 GMT

Consider your options with a triple therapy containing amantadine, in
addition to interferon and ribavirin.

Check out WebMD.com, and of course your physician(s) but in a study
reported (again, see website), 40 patients were treated with the triple-
drug therapy containing amantadine, and 20 patients received the interferon
and ribavirin combination only. The patients received therapy for one year.

Almost half of the patients treated with the triple-drug therapy had
sustained responses to treatment six months after its completion, compared
with just 5% of patients treated with the interferon and ribavirin combo
alone. At one year after the end of therapy, almost 40% of the responding
patients given the three-drug regimen had not relapsed.

Worth checking out. http://my.webmd.com/content/article/28/1728_62277

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